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Clavaviridae


Clavaviridae is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. Prangishvili in 2010.[1] There is one genus in this family (Clavavirus). Within this genus, a single species has been described to date: Aeropyrum pernix bacilliform virus 1 (APBV1).[2]

Clavaviridae
Aeropyrum pernix bacilliform virus 1 (APBV1)
Virus classification
(unranked): Virus
Realm: incertae sedis
Kingdom: incertae sedis
Phylum: incertae sedis
Class: incertae sedis
Order: incertae sedis
Family: Clavaviridae
Genera

The name is derived from the Latin word clava meaning stick.

Virology

 
3D reconstruction of the virion structure of Aeropyrum pernix bacilliform virus 1 (APBV1). Scale bar 10 nm.

The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter.[1][3] One end is pointed and the other is rounded. The structure of the APBV1 virion has been solved by cryo-electron microscopy to near-atomic resolution, revealing how the helical particle is built from an alpha-helical major capsid protein with a unique structural fold.[3] Virions are highly thermostable and remain infectious after incubation at 100 °C for 3 h[citation needed]

 
APBV1 genome map

The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome. The genome contains 14 open reading frames, none of which share similarity with sequences in public databases.[citation needed]

Infection with this virus does not cause host cell lysis.[citation needed]

References

  1. ^ a b Mochizuki T, Yoshida T, Tanaka R, Forterre P, Sako Y, Prangishvili D (2010). "Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum, and isolation of the Aeropyrum pernix bacilliform virus 1, APBV1, the first representative of the family Clavaviridae". Virology. 402 (2): 347–54. doi:10.1016/j.virol.2010.03.046. PMID 20430412.
  2. ^ Prangishvili, David; Mochizuki, Tomohiro; Liu, Ying; Krupovic, Mart; ICTV Report Consortium (2019). "ICTV Virus Taxonomy Profile: Clavaviridae". Journal of General Virology. 100 (9): 1267–1268. doi:10.1099/jgv.0.001295. PMID 31271351.
  3. ^ a b Ptchelkine, D; Gillum, A; Mochizuki, T; Lucas-Staat, S; Liu, Y; Krupovic, M; Phillips, SEV; Prangishvili, D; Huiskonen, JT (10 November 2017). "Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging". Nature Communications. 8 (1): 1436. Bibcode:2017NatCo...8.1436P. doi:10.1038/s41467-017-01668-0. PMC 5681674. PMID 29127347.

External links

  • ICTV Report: Clavaviridae'


clavaviridae, family, double, stranded, viruses, that, infect, archaea, this, family, first, described, team, prangishvili, 2010, there, genus, this, family, clavavirus, within, this, genus, single, species, been, described, date, aeropyrum, pernix, bacillifor. Clavaviridae is a family of double stranded viruses that infect archaea This family was first described by the team led by D Prangishvili in 2010 1 There is one genus in this family Clavavirus Within this genus a single species has been described to date Aeropyrum pernix bacilliform virus 1 APBV1 2 ClavaviridaeAeropyrum pernix bacilliform virus 1 APBV1 Virus classification unranked VirusRealm incertae sedisKingdom incertae sedisPhylum incertae sedisClass incertae sedisOrder incertae sedisFamily ClavaviridaeGeneraClavavirusThe name is derived from the Latin word clava meaning stick Virology Edit 3D reconstruction of the virion structure of Aeropyrum pernix bacilliform virus 1 APBV1 Scale bar 10 nm The virons are bacilliform in shape and 143 nanometers nm in length and 15 8 nm in diameter 1 3 One end is pointed and the other is rounded The structure of the APBV1 virion has been solved by cryo electron microscopy to near atomic resolution revealing how the helical particle is built from an alpha helical major capsid protein with a unique structural fold 3 Virions are highly thermostable and remain infectious after incubation at 100 C for 3 h citation needed APBV1 genome map The genome is a circular double stranded DNA molecule of 5 3 kb It does not integrate into the host genome The genome contains 14 open reading frames none of which share similarity with sequences in public databases citation needed Infection with this virus does not cause host cell lysis citation needed References Edit a b Mochizuki T Yoshida T Tanaka R Forterre P Sako Y Prangishvili D 2010 Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum and isolation of the Aeropyrum pernix bacilliform virus 1 APBV1 the first representative of the family Clavaviridae Virology 402 2 347 54 doi 10 1016 j virol 2010 03 046 PMID 20430412 Prangishvili David Mochizuki Tomohiro Liu Ying Krupovic Mart ICTV Report Consortium 2019 ICTV Virus Taxonomy Profile Clavaviridae Journal of General Virology 100 9 1267 1268 doi 10 1099 jgv 0 001295 PMID 31271351 a b Ptchelkine D Gillum A Mochizuki T Lucas Staat S Liu Y Krupovic M Phillips SEV Prangishvili D Huiskonen JT 10 November 2017 Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging Nature Communications 8 1 1436 Bibcode 2017NatCo 8 1436P doi 10 1038 s41467 017 01668 0 PMC 5681674 PMID 29127347 External links EditICTV Report Clavaviridae This virus related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Clavaviridae amp oldid 1120533946, wikipedia, wiki, book, books, library,

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