^ abBräuner-Osborne H, Wellendorph P, Jensen AA (2007). "Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors". Curr Drug Targets. 8 (1): 169–84. doi:10.2174/138945007779315614. PMID 17266540.
class, gpcr, class, protein, coupled, receptors, interpro, ipr000337, class, protein, coupled, receptors, that, include, metabotropic, glutamate, receptors, interpro, ipr000162, several, additional, receptors, transmembrane, receptor, metabotropic, glutamate, . The class C G protein coupled receptors InterPro IPR000337 are a class of G protein coupled receptors that include the metabotropic glutamate receptors InterPro IPR000162 and several additional receptors 1 7 transmembrane receptor metabotropic glutamate family IdentifiersSymbol7tm 3PfamPF00003InterProIPR000337PROSITEPDOC00754TCDB9 A 14OPM superfamily6OPM protein4or2CDDcd13953Available protein structures Pfam structures ECOD PDBRCSB PDB PDBe PDBjPDBsumstructure summaryStructurally they are composed of four elements an N terminal signal sequence a large hydrophilic extracellular agonist binding region containing several conserved cysteine residues which could be involved in disulphide bonds a shorter region containing seven transmembrane domains and a C terminal cytoplasmic domain of variable length 1 This protein family includes metabotropic glutamate receptors the extracellular calcium sensing receptors the gamma amino butyric acid GABA type B receptors and the vomeronasal type 2 receptors Contents 1 Subfamilies 1 1 Calcium sensing receptor related 1 2 GABAB receptors 1 3 Metabotropic glutamate receptors 1 4 RAIG 1 5 Taste receptors 1 6 Orphan 1 7 Other 2 ReferencesSubfamilies editCalcium sensing receptor related edit extracellular calcium sensing receptor related InterPro IPR000068 Calcium sensing receptor CASR GPRC6A GPRC6A GABAB receptors edit GABAB receptor gamma aminobutyric acid InterPro IPR002455 GABAB receptor 1 GABBR1 GABAB receptor 2 GABBR2 Metabotropic glutamate receptors edit Metabotropic glutamate receptors mGluR InterPro IPR000162 mGluR1 GRM1 mGluR2 GRM2 mGluR3 GRM3 mGluR4 GRM4 mGluR5 GRM5 mGluR6 GRM6 mGluR7 GRM7 mGluR8 GRM8 RAIG edit Retinoic acid inducible orphan G protein coupled receptors RAIG RAIG1 GPRC5A RAIG2 GPRC5B RAIG3 GPRC5C RAIG4 GPRC5D Taste receptors edit Taste receptor Taste receptor type 1 member 1 TAS1R1 Taste receptor type 1 member 2 TAS1R2 Taste receptor type 1 member 3 TAS1R3 Orphan edit Class C Orphan receptors GPR158 GPR158 GPR179 GPR179 GPR156 GPR156 Other edit Bride of sevenless protein InterPro IPR002956 Vomeronasal receptor type 2 InterPro IPR004073References edit a b Brauner Osborne H Wellendorph P Jensen AA 2007 Structure pharmacology and therapeutic prospects of family C G protein coupled receptors Curr Drug Targets 8 1 169 84 doi 10 2174 138945007779315614 PMID 17266540 nbsp This transmembrane receptor related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Class C GPCR amp oldid 1095505760, wikipedia, wiki, book, books, library,
