This gene encodes a member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains and one von Willebrand factor A domain. The encoded protein may be involved in membrane trafficking. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Referencesedit
^ abcGRCh38: Ensembl release 89: ENSG00000178773 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000034796 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
cpne7, copine, protein, that, humans, encoded, gene, identifiersaliases, copine, 7external, idsomim, 605689, 2142747, homologene, 65128, genecards, gene, location, human, chromosome, human, band16q24, 3start89, end89, gene, location, mouse, chromosome, mouse, . Copine 7 is a protein that in humans is encoded by the CPNE7 gene 5 CPNE7IdentifiersAliasesCPNE7 copine 7External IDsOMIM 605689 MGI 2142747 HomoloGene 65128 GeneCards CPNE7Gene location Human Chr Chromosome 16 human 1 Band16q24 3Start89 575 758 bp 1 End89 597 246 bp 1 Gene location Mouse Chr Chromosome 8 mouse 2 Band8 8 E1Start123 844 113 bp 2 End123 861 921 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed instromal cell of endometriumparotid glandpituitary glandcingulate gyrusanterior pituitaryhypothalamusright ventricleBrodmann area 9amygdalaprefrontal cortexTop expressed insubiculumhippocampus propermedial dorsal nucleussuperior frontal gyrusRegion I of hippocampus propersubstantia nigraventral tegmental arealenshypothalamusJacobson s organMore reference expression dataBioGPSn aGene ontologyMolecular functionprotein binding transporter activity calcium dependent phospholipid bindingCellular componentcytoplasm plasma membrane extracellular exosome membrane nucleusBiological processcellular response to calcium ion glycerophospholipid biosynthetic process lipid metabolism transportSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez27132102278EnsemblENSG00000178773ENSMUSG00000034796UniProtQ9UBL6Q0VE82RefSeq mRNA NM 014427NM 153636NM 170684RefSeq protein NP 055242NP 705900NP 733785Location UCSC Chr 16 89 58 89 6 MbChr 8 123 84 123 86 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseFunction editThis gene encodes a member of the copine family which is composed of calcium dependent membrane binding proteins The gene product contains two N terminal C2 domains and one von Willebrand factor A domain The encoded protein may be involved in membrane trafficking Two alternatively spliced transcript variants encoding different isoforms have been found for this gene References edit a b c GRCh38 Ensembl release 89 ENSG00000178773 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000034796 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene Copine 7 Retrieved 2017 01 19 Further reading editThis article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on human chromosome 16 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CPNE7 amp oldid 1195481763, wikipedia, wiki, book, books, library,
