Coatomer subunit gamma is a protein that in humans is encoded by the COPGgene.[5][6] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000181789 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030058 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ abcdFutatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
^"Entrez Gene: COPG coatomer protein complex, subunit gamma".
^Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2). Germany: 77–85. doi:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085.
^Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1). UNITED STATES: 53–61. doi:10.1083/jcb.135.1.53. ISSN 0021-9525. PMC2121028. PMID 8858162.
^Lowe, M; Kreis T E (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48). UNITED STATES: 30725–30. doi:10.1074/jbc.271.48.30725. ISSN 0021-9258. PMID 8940050.
External linksedit
Human COPG1 genome location and COPG1 gene details page in the UCSC Genome Browser.
Further readingedit
Lowe M, Kreis TE (1997). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. PMID 8940050.
Pavel J, Harter C, Wieland FT (1998). "Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex". Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2140–5. Bibcode:1998PNAS...95.2140P. doi:10.1073/pnas.95.5.2140. PMC19276. PMID 9482852.
Fischer KD, Helms JB, Zhao L, Wieland FT (2000). "Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles". Methods. 20 (4): 455–64. doi:10.1006/meth.2000.0958. PMID 10720466.
Eugster A, Frigerio G, Dale M, Duden R (2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMC306616. PMID 10921873.
Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC16901. PMID 10931946.
Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport". Mol. Biol. Cell. 11 (9): 3155–68. doi:10.1091/mbc.11.9.3155. PMC14982. PMID 10982407.
Hahn Y, Lee YJ, Yun JH, et al. (2000). "Duplication of genes encoding non-clathrin coat protein gamma-COP in vertebrate, insect and plant evolution". FEBS Lett. 482 (1–2): 31–6. doi:10.1016/S0014-5793(00)02033-0. PMID 11018518. S2CID 36356269.
Paulsson KM, Kleijmeer MJ, Griffith J, et al. (2002). "Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum". J. Biol. Chem. 277 (21): 18266–71. doi:10.1074/jbc.M201388200. PMID 11884415.
Bermak JC, Li M, Bullock C, et al. (2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2): 77–85. doi:10.1078/0171-9335-00222. PMID 11893085.
Kanzaki M, Watson RT, Hou JC, et al. (2003). "Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes". Mol. Biol. Cell. 13 (7): 2334–46. doi:10.1091/mbc.01-10-0490. PMC117317. PMID 12134073.
Xu Y, Martin S, James DE, Hong W (2003). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC129961. PMID 12388752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Rohde HM, Cheong FY, Konrad G, et al. (2004). "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex". J. Biol. Chem. 278 (52): 52689–99. doi:10.1074/jbc.M307983200. PMID 14527956.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC1847948. PMID 17353931.
This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.
copg, coatomer, subunit, gamma, protein, that, humans, encoded, gene, seven, proteins, copi, coatomer, complex, that, coats, vesicles, they, from, golgi, complex, 1available, structurespdbortholog, search, pdbe, rcsblist, codes1r4xidentifiersaliases1, coatomer. Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene 5 6 It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex 5 COPG1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes1R4XIdentifiersAliasesCOPG1 COPG coatomer protein complex subunit gamma 1 COPI coat complex subunit gamma 1External IDsOMIM 615525 MGI 1858696 HomoloGene 56745 GeneCards COPG1Gene location Human Chr Chromosome 3 human 1 Band3q21 3Start129 249 606 bp 1 End129 277 773 bp 1 Gene location Mouse Chr Chromosome 6 mouse 2 Band6 D1 6 39 13 cMStart87 864 796 bp 2 End87 890 577 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed instromal cell of endometriumanterior pituitarybody of pancreasislet of Langerhansminor salivary glandsright lobe of thyroid glandbody of stomachright adrenal glandrectumleft lobe of thyroid glandTop expressed inyolk sacmolarsuperior frontal gyrussupraoptic nucleuspituitary glanddermisislet of Langerhanscrypt of lieberkuhn of small intestinefacial motor nucleuscerebellar cortexMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionprotein binding structural molecule activityCellular componentcytoplasm membrane coat COPI coated vesicle membrane membrane transport vesicle cytosol cytoplasmic vesicle Golgi apparatus Golgi membrane COPI vesicle coat endoplasmic reticulum membrane endoplasmic reticulum endoplasmic reticulum Golgi intermediate compartmentBiological processretrograde vesicle mediated transport Golgi to endoplasmic reticulum protein transport organelle transport along microtubule intracellular protein transport establishment of Golgi localization endoplasmic reticulum to Golgi vesicle mediated transport vesicle mediated transport intra Golgi vesicle mediated transport protein secretionSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez2282054161EnsemblENSG00000181789ENSMUSG00000030058UniProtQ9Y678Q9QZE5RefSeq mRNA NM 016128NM 017477NM 201244RefSeq protein NP 057212NP 059505NP 957696Location UCSC Chr 3 129 25 129 28 MbChr 6 87 86 87 89 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Contents 1 Interactions 2 References 3 External links 4 Further readingInteractions editCOPG has been shown to interact with Dopamine receptor D1 7 COPZ1 5 8 and COPB1 5 9 References edit a b c GRCh38 Ensembl release 89 ENSG00000181789 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000030058 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine a b c d Futatsumori M Kasai K Takatsu H Shin HW Nakayama K February 2001 Identification and characterization of novel isoforms of COP I subunits J Biochem 128 5 793 801 doi 10 1093 oxfordjournals jbchem a022817 PMID 11056392 Entrez Gene COPG coatomer protein complex subunit gamma Bermak Jason C Li Ming Bullock Clayton Weingarten Paul Zhou Qun Yong February 2002 Interaction of gamma COP with a transport motif in the D1 receptor C terminus Eur J Cell Biol 81 2 Germany 77 85 doi 10 1078 0171 9335 00222 ISSN 0171 9335 PMID 11893085 Faulstich D Auerbach S Orci L Ravazzola M Wegchingel S Lottspeich F Stenbeck G Harter C Wieland F T Tschochner H October 1996 Architecture of coatomer molecular characterization of delta COP and protein interactions within the complex PDF J Cell Biol 135 1 UNITED STATES 53 61 doi 10 1083 jcb 135 1 53 ISSN 0021 9525 PMC 2121028 PMID 8858162 Lowe M Kreis T E November 1996 In vivo assembly of coatomer the COP I coat precursor J Biol Chem 271 48 UNITED STATES 30725 30 doi 10 1074 jbc 271 48 30725 ISSN 0021 9258 PMID 8940050 External links editHuman COPG1 genome location and COPG1 gene details page in the UCSC Genome Browser Further reading editLowe M Kreis TE 1997 In vivo assembly of coatomer the COP I coat precursor J Biol Chem 271 48 30725 30 doi 10 1074 jbc 271 48 30725 PMID 8940050 Pavel J Harter C Wieland FT 1998 Reversible dissociation of coatomer functional characterization of a beta delta coat protein subcomplex Proc Natl Acad Sci U S A 95 5 2140 5 Bibcode 1998PNAS 95 2140P doi 10 1073 pnas 95 5 2140 PMC 19276 PMID 9482852 Fischer KD Helms JB Zhao L Wieland FT 2000 Site specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles Methods 20 4 455 64 doi 10 1006 meth 2000 0958 PMID 10720466 Eugster A Frigerio G Dale M Duden R 2000 COP I domains required for coatomer integrity and novel interactions with ARF and ARF GAP EMBO J 19 15 3905 17 doi 10 1093 emboj 19 15 3905 PMC 306616 PMID 10921873 Hu RM Han ZG Song HD et al 2000 Gene expression profiling in the human hypothalamus pituitary adrenal axis and full length cDNA cloning Proc Natl Acad Sci U S A 97 17 9543 8 Bibcode 2000PNAS 97 9543H doi 10 1073 pnas 160270997 PMC 16901 PMID 10931946 Sullivan BM Harrison Lavoie KJ Marshansky V et al 2000 RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport Mol Biol Cell 11 9 3155 68 doi 10 1091 mbc 11 9 3155 PMC 14982 PMID 10982407 Hahn Y Lee YJ Yun JH et al 2000 Duplication of genes encoding non clathrin coat protein gamma COP in vertebrate insect and plant evolution FEBS Lett 482 1 2 31 6 doi 10 1016 S0014 5793 00 02033 0 PMID 11018518 S2CID 36356269 Paulsson KM Kleijmeer MJ Griffith J et al 2002 Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex MHC class I molecules from the Golgi complex to the endoplasmic reticulum J Biol Chem 277 21 18266 71 doi 10 1074 jbc M201388200 PMID 11884415 Bermak JC Li M Bullock C et al 2002 Interaction of gamma COP with a transport motif in the D1 receptor C terminus Eur J Cell Biol 81 2 77 85 doi 10 1078 0171 9335 00222 PMID 11893085 Kanzaki M Watson RT Hou JC et al 2003 Small GTP binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes Mol Biol Cell 13 7 2334 46 doi 10 1091 mbc 01 10 0490 PMC 117317 PMID 12134073 Xu Y Martin S James DE Hong W 2003 GS15 forms a SNARE complex with syntaxin 5 GS28 and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus Mol Biol Cell 13 10 3493 507 doi 10 1091 mbc E02 01 0004 PMC 129961 PMID 12388752 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Rohde HM Cheong FY Konrad G et al 2004 The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex J Biol Chem 278 52 52689 99 doi 10 1074 jbc M307983200 PMID 14527956 Watson PJ Frigerio G Collins BM et al 2004 Gamma COP appendage domain structure and function Traffic 5 2 79 88 doi 10 1111 j 1600 0854 2004 00158 x PMID 14690497 S2CID 24249308 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ewing RM Chu P Elisma F et al 2007 Large scale mapping of human protein protein interactions by mass spectrometry Mol Syst Biol 3 1 89 doi 10 1038 msb4100134 PMC 1847948 PMID 17353931 nbsp This article on a gene on human chromosome 3 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title COPG amp oldid 1180523167, wikipedia, wiki, book, books, library,
