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Wikipedia

CENTG3

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene.[5]

AGAP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAGAP3, AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
External IDsOMIM: 616813 MGI: 2183446 HomoloGene: 23742 GeneCards: AGAP3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256431
NM_139153
NM_001359881

RefSeq (protein)

n/a

Location (UCSC)Chr 7: 151.09 – 151.14 MbChr 5: 24.66 – 24.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133612 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023353 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CENTG3 centaurin, gamma 3".

External links edit

Further reading edit

  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–1292. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Qin Q, Inatome R, Hotta A, et al. (2006). "A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein". J. Cell Biol. 172 (4): 497–504. doi:10.1083/jcb.200505079. PMC 2063670. PMID 16461359.
  • Meurer S, Pioch S, Wagner K, et al. (2005). "AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase". J. Biol. Chem. 279 (47): 49346–49354. doi:10.1074/jbc.M410565200. PMID 15381706.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
  • Surks HK, Richards CT, Mendelsohn ME (2004). "Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA". J. Biol. Chem. 278 (51): 51484–51493. doi:10.1074/jbc.M305622200. PMID 14506264.
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–772. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Xia C, Ma W, Stafford LJ, et al. (2003). "GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins". Mol. Cell. Biol. 23 (7): 2476–2488. doi:10.1128/MCB.23.7.2476-2488.2003. PMC 150724. PMID 12640130.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


centg3, with, gtpase, repeat, domain, containing, protein, enzyme, that, humans, encoded, agap3, gene, agap3available, structurespdbortholog, search, pdbe, rcsblist, codes3ihwidentifiersaliasesagap3, agap, crag, mrip, arfgap, with, gtpase, domain, ankyrin, rep. Arf GAP with GTPase ANK repeat and PH domain containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene 5 AGAP3Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes3IHWIdentifiersAliasesAGAP3 AGAP 3 CENTG3 CRAG MRIP 1 cnt g3 ArfGAP with GTPase domain ankyrin repeat and PH domain 3External IDsOMIM 616813 MGI 2183446 HomoloGene 23742 GeneCards AGAP3Gene location Human Chr Chromosome 7 human 1 Band7q36 1Start151 085 831 bp 1 End151 144 436 bp 1 Gene location Mouse Chr Chromosome 5 mouse 2 Band5 5 A3Start24 657 175 bp 2 End24 707 045 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inBrodmann area 9cingulate gyrusprefrontal cortexamygdalahypothalamusnucleus accumbensanterior pituitarycanal of the cervixputamenright lungTop expressed insuperior frontal gyruslipcerebellar cortexsacculeyolk sacesophagusotic placodeneural tubehippocampus properentorhinal cortexMore reference expression dataBioGPSn aGene ontologyMolecular functionnucleotide binding GTP binding metal ion binding GTPase activator activity GTPase activity polyubiquitin modification dependent protein bindingCellular componentmembrane nucleus cytoplasm cell peripheryBiological processpositive regulation of GTPase activity signal transduction cellular response to reactive oxygen species proteasome mediated ubiquitin dependent protein catabolic processSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez116988213990EnsemblENSG00000133612ENSMUSG00000023353UniProtQ96P47Q86ST5Q8VHH5RefSeq mRNA NM 001042535NM 001281300NM 001308304NM 001308305NM 031946NM 001350102NM 001350103NM 001350104NM 001256431NM 139153NM 001359881RefSeq protein NP 001036000NP 001268229NP 001295233NP 001295234NP 114152NP 001337031NP 001337032NP 001337033NP 001036000 1NP 001295233 1NP 001295234 1n aLocation UCSC Chr 7 151 09 151 14 MbChr 5 24 66 24 71 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000133612 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000023353 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene CENTG3 centaurin gamma 3 External links editHuman AGAP3 genome location and AGAP3 gene details page in the UCSC Genome Browser Further reading editBeausoleil SA Villen J Gerber SA et al 2006 A probability based approach for high throughput protein phosphorylation analysis and site localization Nat Biotechnol 24 10 1285 1292 doi 10 1038 nbt1240 PMID 16964243 S2CID 14294292 Qin Q Inatome R Hotta A et al 2006 A novel GTPase CRAG mediates promyelocytic leukemia protein associated nuclear body formation and degradation of expanded polyglutamine protein J Cell Biol 172 4 497 504 doi 10 1083 jcb 200505079 PMC 2063670 PMID 16461359 Meurer S Pioch S Wagner K et al 2005 AGAP1 a novel binding partner of nitric oxide sensitive guanylyl cyclase J Biol Chem 279 47 49346 49354 doi 10 1074 jbc M410565200 PMID 15381706 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 45 doi 10 1038 ng1285 PMID 14702039 Surks HK Richards CT Mendelsohn ME 2004 Myosin phosphatase Rho interacting protein A new member of the myosin phosphatase complex that directly binds RhoA J Biol Chem 278 51 51484 51493 doi 10 1074 jbc M305622200 PMID 14506264 Scherer SW Cheung J MacDonald JR et al 2003 Human chromosome 7 DNA sequence and biology Science 300 5620 767 772 Bibcode 2003Sci 300 767S doi 10 1126 science 1083423 PMC 2882961 PMID 12690205 Xia C Ma W Stafford LJ et al 2003 GGAPs a new family of bifunctional GTP binding and GTPase activating proteins Mol Cell Biol 23 7 2476 2488 doi 10 1128 MCB 23 7 2476 2488 2003 PMC 150724 PMID 12640130 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 16903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 nbsp This article on a gene on human chromosome 7 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CENTG3 amp oldid 1115842215, wikipedia, wiki, book, books, library,

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