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Wikipedia

CDR2 (gene)

Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene.[5][6]

CDR2
Identifiers
AliasesCDR2, CDR62, Yo, cerebellar degeneration related protein 2
External IDsOMIM: 117340 MGI: 1100885 HomoloGene: 7262 GeneCards: CDR2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001802

NM_007672
NM_001354986

RefSeq (protein)

NP_001793

NP_031698
NP_001341915

Location (UCSC)Chr 16: 22.35 – 22.44 MbChr 7: 120.56 – 120.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140743 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030878 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fathallah-Shaykh H, Wolf S, Wong E, Posner JB, Furneaux HM (May 1991). "Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration". Proc Natl Acad Sci U S A. 88 (8): 3451–4. Bibcode:1991PNAS...88.3451F. doi:10.1073/pnas.88.8.3451. PMC 51465. PMID 2014264.
  6. ^ "Entrez Gene: CDR2 cerebellar degeneration-related protein 2, 62kDa".

Further reading edit

  • Gress T, Baldini A, Rocchi M, et al. (1992). "In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1". Genomics. 13 (4): 1340–2. doi:10.1016/0888-7543(92)90063-X. PMID 1505970.
  • Sakai K, Mitchell DJ, Tsukamoto T, Steinman L (1992). "Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration". Ann. Neurol. 30 (5): 738. doi:10.1002/ana.410300523. PMID 1763903.
  • Sakai K, Mitchell DJ, Tsukamoto T, Steinman L (1991). "Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration". Ann. Neurol. 28 (5): 692–8. doi:10.1002/ana.410280515. PMID 2260856. S2CID 28532317.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Fletcher CF, Okano HJ, Gilbert DJ, et al. (1998). "Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens". Genomics. 45 (2): 313–9. doi:10.1006/geno.1997.4925. PMID 9344654.
  • Takanaga H, Mukai H, Shibata H, et al. (1998). "PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor". Exp. Cell Res. 241 (2): 363–72. doi:10.1006/excr.1998.4060. PMID 9637778.
  • Okano HJ, Park WY, Corradi JP, Darnell RB (1999). "The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival". Genes Dev. 13 (16): 2087–97. doi:10.1101/gad.13.16.2087. PMC 316965. PMID 10465786.
  • Sakai K, Shirakawa T, Li Y, et al. (2002). "Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X.". Mol. Cell. Neurosci. 19 (4): 477–84. doi:10.1006/mcne.2001.1059. PMID 11988016. S2CID 26659745.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Sutton IJ, Steele J, Savage CO, et al. (2004). "An interferon-gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies". J. Neuroimmunol. 150 (1–2): 98–106. doi:10.1016/j.jneuroim.2003.12.026. PMID 15081253. S2CID 45697226.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Balbo M, Barel M, Lottin-Divoux S, et al. (2005). "Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21)". FEMS Microbiol. Lett. 249 (2): 359–66. doi:10.1016/j.femsle.2005.06.052. PMID 16054780.

External links edit


cdr2, gene, confused, with, mitosis, inducer, protein, kinase, cdr2, cerebellar, degeneration, related, protein, protein, that, humans, encoded, cdr2, gene, cdr2identifiersaliasescdr2, cdr62, cerebellar, degeneration, related, protein, 2external, idsomim, 1173. Not to be confused with Mitosis inducer protein kinase cdr2 Cerebellar degeneration related protein 2 is a protein that in humans is encoded by the CDR2 gene 5 6 CDR2IdentifiersAliasesCDR2 CDR62 Yo cerebellar degeneration related protein 2External IDsOMIM 117340 MGI 1100885 HomoloGene 7262 GeneCards CDR2Gene location Human Chr Chromosome 16 human 1 Band16p12 2Start22 345 936 bp 1 End22 437 165 bp 1 Gene location Mouse Chr Chromosome 7 mouse 2 Band7 F2 7 65 04 cMStart120 556 259 bp 2 End120 581 535 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed insecondary oocyteretinal pigment epitheliumjejunal mucosaAchilles tendonspermleft lobe of thyroid glandright lobe of thyroid glandgastric mucosaglomerulusmetanephric glomerulusTop expressed inbloodsacculeretinal pigment epitheliumotic placodesecondary oocyteduodenumfacial motor nucleusspleenbody of femurjejunumMore reference expression dataBioGPSMore reference expression dataOrthologsSpeciesHumanMouseEntrez103912585EnsemblENSG00000140743ENSMUSG00000030878UniProtQ01850P97817RefSeq mRNA NM 001802NM 007672NM 001354986RefSeq protein NP 001793NP 031698NP 001341915Location UCSC Chr 16 22 35 22 44 MbChr 7 120 56 120 58 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Contents 1 See also 2 References 3 Further reading 4 External linksSee also editCerebellar degeneration related protein 1References edit a b c GRCh38 Ensembl release 89 ENSG00000140743 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000030878 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Fathallah Shaykh H Wolf S Wong E Posner JB Furneaux HM May 1991 Cloning of a leucine zipper protein recognized by the sera of patients with antibody associated paraneoplastic cerebellar degeneration Proc Natl Acad Sci U S A 88 8 3451 4 Bibcode 1991PNAS 88 3451F doi 10 1073 pnas 88 8 3451 PMC 51465 PMID 2014264 Entrez Gene CDR2 cerebellar degeneration related protein 2 62kDa Further reading editGress T Baldini A Rocchi M et al 1992 In situ mapping of the gene coding for a leucine zipper DNA binding protein CDR62 to 16p12 16p13 1 Genomics 13 4 1340 2 doi 10 1016 0888 7543 92 90063 X PMID 1505970 Sakai K Mitchell DJ Tsukamoto T Steinman L 1992 Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration Ann Neurol 30 5 738 doi 10 1002 ana 410300523 PMID 1763903 Sakai K Mitchell DJ Tsukamoto T Steinman L 1991 Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration Ann Neurol 28 5 692 8 doi 10 1002 ana 410280515 PMID 2260856 S2CID 28532317 Bonaldo MF Lennon G Soares MB 1997 Normalization and subtraction two approaches to facilitate gene discovery Genome Res 6 9 791 806 doi 10 1101 gr 6 9 791 PMID 8889548 Fletcher CF Okano HJ Gilbert DJ et al 1998 Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens Genomics 45 2 313 9 doi 10 1006 geno 1997 4925 PMID 9344654 Takanaga H Mukai H Shibata H et al 1998 PKN interacts with a paraneoplastic cerebellar degeneration associated antigen which is a potential transcription factor Exp Cell Res 241 2 363 72 doi 10 1006 excr 1998 4060 PMID 9637778 Okano HJ Park WY Corradi JP Darnell RB 1999 The cytoplasmic Purkinje onconeural antigen cdr2 down regulates c Myc function implications for neuronal and tumor cell survival Genes Dev 13 16 2087 97 doi 10 1101 gad 13 16 2087 PMC 316965 PMID 10465786 Sakai K Shirakawa T Li Y et al 2002 Interaction of a paraneoplastic cerebellar degeneration associated neuronal protein with the nuclear helix loop helix leucine zipper protein MRG X Mol Cell Neurosci 19 4 477 84 doi 10 1006 mcne 2001 1059 PMID 11988016 S2CID 26659745 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Sutton IJ Steele J Savage CO et al 2004 An interferon gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti Yo antibodies J Neuroimmunol 150 1 2 98 106 doi 10 1016 j jneuroim 2003 12 026 PMID 15081253 S2CID 45697226 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Balbo M Barel M Lottin Divoux S et al 2005 Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein Barr virus receptor gp140 EBV C3dR CR2 CD21 FEMS Microbiol Lett 249 2 359 66 doi 10 1016 j femsle 2005 06 052 PMID 16054780 External links editCDR2 human gene location in the UCSC Genome Browser CDR2 human gene details in the UCSC Genome Browser nbsp This article on a gene on human chromosome 16 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CDR2 gene amp oldid 1175070663, wikipedia, wiki, book, books, library,

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