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Wikipedia

CD5L

CD5 antigen-like is a protein (also known as AIM Apoptosis Inhibitor of Macrophages) that in humans is encoded by the CD5L gene.[5][6]

CD5L
Identifiers
AliasesCD5L, AIM, API6, PRO229, SP-ALPHA, Spalpha, CT-2, hAIM, CD5 molecule like
External IDsOMIM: 602592 MGI: 1334419 HomoloGene: 55936 GeneCards: CD5L
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005894
NM_001347698

NM_009690

RefSeq (protein)

NP_001334627
NP_005885

NP_033820

Location (UCSC)Chr 1: 157.83 – 157.9 MbChr 3: 87.27 – 87.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000073754 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015854 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gebe JA, Kiener PA, Ring HZ, Li X, Francke U, Aruffo A (Apr 1997). "Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins". J Biol Chem. 272 (10): 6151–8. doi:10.1074/jbc.272.10.6151. PMID 9045627.
  6. ^ "Entrez Gene: CD5L CD5 molecule-like".

External links edit

Further reading edit

  • Tissot JD, Schifferli JA, Hochstrasser DF, et al. (1994). "Two-dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM-associated peptide". J. Immunol. Methods. 173 (1): 63–75. doi:10.1016/0022-1759(94)90284-4. PMID 8034987.
  • Tissot JD, Sanchez JC, Vuadens F, et al. (2002). "IgM are associated to Sp alpha (CD5 antigen-like)". Electrophoresis. 23 (7–8): 1203–6. doi:10.1002/1522-2683(200204)23:7/8<1203::AID-ELPS1203>3.0.CO;2-1. PMID 11981870. S2CID 94662015.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell. Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Sarrias MR, Roselló S, Sánchez-Barbero F, et al. (2005). "A role for human Sp alpha as a pattern recognition receptor". J. Biol. Chem. 280 (42): 35391–8. doi:10.1074/jbc.M505042200. hdl:2445/176948. PMID 16030018.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.


cd5l, antigen, like, protein, also, known, apoptosis, inhibitor, macrophages, that, humans, encoded, gene, identifiersaliases, api6, pro229, alpha, spalpha, haim, molecule, likeexternal, idsomim, 602592, 1334419, homologene, 55936, genecards, gene, location, h. CD5 antigen like is a protein also known as AIM Apoptosis Inhibitor of Macrophages that in humans is encoded by the CD5L gene 5 6 CD5LIdentifiersAliasesCD5L AIM API6 PRO229 SP ALPHA Spalpha CT 2 hAIM CD5 molecule likeExternal IDsOMIM 602592 MGI 1334419 HomoloGene 55936 GeneCards CD5LGene location Human Chr Chromosome 1 human 1 Band1q23 1Start157 830 911 bp 1 End157 898 256 bp 1 Gene location Mouse Chr Chromosome 3 mouse 2 Band3 3 F1Start87 265 188 bp 2 End87 278 380 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inspleentrabecular boneliverright lobe of liverlymph nodebone marrowbone marrow cellsplacentaappendixleft ventricleTop expressed inleft lobe of liverspleencalvariasubcutaneous adipose tissuespermatidseminiferous tubulewhite adipose tissuesexually immature organismmeningesthoracic diaphragmMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionscavenger receptor activityCellular componentcytoplasm extracellular region extracellular exosome blood microparticle membrane extracellular space plasma membrane cell surfaceBiological processcellular defense response inflammatory response receptor mediated endocytosis immune system process apoptotic process vesicle mediated transport regulation of complement activation positive regulation of complement dependent cytotoxicity endocytosisSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez92211801EnsemblENSG00000073754ENSMUSG00000015854UniProtO43866Q9QWK4RefSeq mRNA NM 005894NM 001347698NM 009690RefSeq protein NP 001334627NP 005885NP 033820Location UCSC Chr 1 157 83 157 9 MbChr 3 87 27 87 28 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000073754 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000015854 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Gebe JA Kiener PA Ring HZ Li X Francke U Aruffo A Apr 1997 Molecular cloning mapping to human chromosome 1 q21 q23 and cell binding characteristics of Spalpha a new member of the scavenger receptor cysteine rich SRCR family of proteins J Biol Chem 272 10 6151 8 doi 10 1074 jbc 272 10 6151 PMID 9045627 Entrez Gene CD5L CD5 molecule like External links editHuman CD5L genome location and CD5L gene details page in the UCSC Genome Browser Further reading editTissot JD Schifferli JA Hochstrasser DF et al 1994 Two dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM associated peptide J Immunol Methods 173 1 63 75 doi 10 1016 0022 1759 94 90284 4 PMID 8034987 Tissot JD Sanchez JC Vuadens F et al 2002 IgM are associated to Sp alpha CD5 antigen like Electrophoresis 23 7 8 1203 6 doi 10 1002 1522 2683 200204 23 7 8 lt 1203 AID ELPS1203 gt 3 0 CO 2 1 PMID 11981870 S2CID 94662015 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Clark HF Gurney AL Abaya E et al 2003 The Secreted Protein Discovery Initiative SPDI a Large Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins A Bioinformatics Assessment Genome Res 13 10 2265 70 doi 10 1101 gr 1293003 PMC 403697 PMID 12975309 Anderson NL Polanski M Pieper R et al 2004 The human plasma proteome a nonredundant list developed by combination of four separate sources Mol Cell Proteomics 3 4 311 26 doi 10 1074 mcp M300127 MCP200 PMID 14718574 Zhang Z Henzel WJ 2005 Signal peptide prediction based on analysis of experimentally verified cleavage sites Protein Sci 13 10 2819 24 doi 10 1110 ps 04682504 PMC 2286551 PMID 15340161 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Sarrias MR Rosello S Sanchez Barbero F et al 2005 A role for human Sp alpha as a pattern recognition receptor J Biol Chem 280 42 35391 8 doi 10 1074 jbc M505042200 hdl 2445 176948 PMID 16030018 Gregory SG Barlow KF McLay KE et al 2006 The DNA sequence and biological annotation of human chromosome 1 Nature 441 7091 315 21 Bibcode 2006Natur 441 315G doi 10 1038 nature04727 PMID 16710414 nbsp This article on a gene on human chromosome 1 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CD5L amp oldid 1200405081, wikipedia, wiki, book, books, library,

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