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Bolasterone

Bolasterone (INN, USAN) (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine.[1][2] It has close structural similarity to testosterone, and like methyltestosterone has a methyl group at C17α in order to increase oral bioavailability.[1] In addition, it is also 7α-methylated, similar to its 7β-methylated isomer calusterone.[1] The medication has a low to moderate ratio of anabolic to androgenic activity, similar to that of fluoxymesterone.[3]

Bolasterone
Clinical data
Trade namesMyagen, Methosarb
Other namesU-19763; NSC-66233; 7α,17α-Dimethyltestosterone; 7α,17α-Dimethylandrost-4-en-17β-ol-3-one
Routes of
administration
By mouth
Identifiers
  • (7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,10,13,17-tetramethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number
  • 1605-89-6 Y
PubChem CID
  • 102146
ChemSpider
  • 92280
UNII
  • T7ZM08F7FU
ChEMBL
  • ChEMBL259548
CompTox Dashboard (EPA)
  • DTXSID40166896
ECHA InfoCard100.015.018
Chemical and physical data
FormulaC21H32O2
Molar mass316.485 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C4\C=C3/[C@]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)C)[C@@H]2[C@H](C)C3)C)(C)CC4
  • InChI=1S/C21H32O2/c1-13-11-14-12-15(22)5-8-19(14,2)16-6-9-20(3)17(18(13)16)7-10-21(20,4)23/h12-13,16-18,23H,5-11H2,1-4H3/t13-,16+,17+,18-,19+,20+,21+/m1/s1
  • Key:IVFYLRMMHVYGJH-VLOLGRDOSA-N

Bolasterone is on the World Anti-Doping Agency's list of prohibited substances,[4] and is therefore banned from use in most major sports.

References

  1. ^ a b c Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 646–. ISBN 978-1-4757-2085-3.
  2. ^ Morton IK, Hall JS (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 52–. ISBN 978-94-011-4439-1.
  3. ^ Kochakian CD (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. pp. 377, 401. ISBN 978-3-642-66353-6.
  4. ^ "The World Anti-Doping Code: The 2020 Prohibited List" (PDF). World Anti-Doping Agency. Retrieved 2019-12-28.


bolasterone, usan, brand, names, myagen, methosarb, former, developmental, code, name, 19763, also, known, 17α, dimethyltestosterone, 17α, alkylated, androgen, anabolic, steroid, which, used, veterinary, medicine, close, structural, similarity, testosterone, l. Bolasterone INN USAN brand names Myagen Methosarb former developmental code name U 19763 also known as 7a 17a dimethyltestosterone is a 17a alkylated androgen anabolic steroid AAS which is used in veterinary medicine 1 2 It has close structural similarity to testosterone and like methyltestosterone has a methyl group at C17a in order to increase oral bioavailability 1 In addition it is also 7a methylated similar to its 7b methylated isomer calusterone 1 The medication has a low to moderate ratio of anabolic to androgenic activity similar to that of fluoxymesterone 3 BolasteroneClinical dataTrade namesMyagen MethosarbOther namesU 19763 NSC 66233 7a 17a Dimethyltestosterone 7a 17a Dimethylandrost 4 en 17b ol 3 oneRoutes ofadministrationBy mouthIdentifiersIUPAC name 7R 8R 9S 10R 13S 14S 17S 17 hydroxy 7 10 13 17 tetramethyl 2 6 7 8 9 11 12 14 15 16 decahydro 1H cyclopenta a phenanthren 3 oneCAS Number1605 89 6 YPubChem CID102146ChemSpider92280UNIIT7ZM08F7FUChEMBLChEMBL259548CompTox Dashboard EPA DTXSID40166896ECHA InfoCard100 015 018Chemical and physical dataFormulaC 21H 32O 2Molar mass316 485 g mol 13D model JSmol Interactive imageSMILES O C4 C C3 C C H 2CC C 1 C H CC C 1 O C C H 2 C H C C3 C C CC4InChI InChI 1S C21H32O2 c1 13 11 14 12 15 22 5 8 19 14 2 16 6 9 20 3 17 18 13 16 7 10 21 20 4 23 h12 13 16 18 23H 5 11H2 1 4H3 t13 16 17 18 19 20 21 m1 s1Key IVFYLRMMHVYGJH VLOLGRDOSA NBolasterone is on the World Anti Doping Agency s list of prohibited substances 4 and is therefore banned from use in most major sports References Edit a b c Elks J 14 November 2014 The Dictionary of Drugs Chemical Data Chemical Data Structures and Bibliographies Springer pp 646 ISBN 978 1 4757 2085 3 Morton IK Hall JS 6 December 2012 Concise Dictionary of Pharmacological Agents Properties and Synonyms Springer Science amp Business Media pp 52 ISBN 978 94 011 4439 1 Kochakian CD 6 December 2012 Anabolic Androgenic Steroids Springer Science amp Business Media pp 377 401 ISBN 978 3 642 66353 6 The World Anti Doping Code The 2020 Prohibited List PDF World Anti Doping Agency Retrieved 2019 12 28 This article about a steroid is a stub You can help Wikipedia by expanding it vte This drug article relating to the genito urinary system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Bolasterone amp oldid 1084541895, wikipedia, wiki, book, books, library,

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