CRL-40,940 (also known as flmodafinil, bisfluoromodafinil and lauflumide) is the bisfluoro analog of modafinil.[1][2][3][4][5] It is a eugeroic as well as a weak dopamine reuptake inhibitor. Its inventors claim that it is more effective than modafinil and adrafinil, with fewer side effects. It was patented in 2013, and pre-clinical trials have been underway since December 2015.[6]
^CA 1199916, Lafon L, "Benzhydrylsulfinylacetamide derivatives", published 28 January 1986
^Cao J, Prisinzano TE, Okunola OM, Kopajtic T, Shook M, Katz JL, Newman AH (October 2010). "Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues". ACS Medicinal Chemistry Letters. 2 (1): 48–52. doi:10.1021/ml1002025. PMC3041981. PMID 21344069.
^US 20130295196, Konofal E, "Lauflumide and the enantiomers thereof, method for preparing same and therapeutic uses thereof", published 7 November 2013
^"Flmodafinil Dosage: How Much Should You Take and When?". modaforum.org. Retrieved 2023-09-26.
^Louis Lafon (18 December 1984). "Patent US 4489095 A - Halogenobenzhydrylsulfinylacetohydroxamic acids". Retrieved 25 July 2015.
also, known, flmodafinil, bisfluoromodafinil, lauflumide, bisfluoro, analog, modafinil, eugeroic, well, weak, dopamine, reuptake, inhibitor, inventors, claim, that, more, effective, than, modafinil, adrafinil, with, fewer, side, effects, patented, 2013, clinic. CRL 40 940 also known as flmodafinil bisfluoromodafinil and lauflumide is the bisfluoro analog of modafinil 1 2 3 4 5 It is a eugeroic as well as a weak dopamine reuptake inhibitor Its inventors claim that it is more effective than modafinil and adrafinil with fewer side effects It was patented in 2013 and pre clinical trials have been underway since December 2015 6 CRL 40 940IdentifiersIUPAC name 2 Amino 2 oxoethyl bis 4 fluorophenyl methyl sulfoniumolateCAS Number90280 13 0PubChem CID13271852ChemSpider26386803UNII174R2IG4T0CompTox Dashboard EPA DTXSID00533646Chemical and physical dataFormulaC 15H 13F 2N O 2SMolar mass309 33 g mol 13D model JSmol Interactive imageSMILES C1 CC CC C1C C2 CC C C C2 F S O CC O N FInChI InChI 1S C15H13F2NO2S c16 12 5 1 10 2 6 12 15 21 20 9 14 18 19 11 3 7 13 17 8 4 11 h1 8 15H 9H2 H2 18 19 Key YEAQNUMCWMRYMU UHFFFAOYSA NSee also editAdrafinil Armodafinil CE 123 CRL 40 941 FluorenolReferences edit CA 1199916 Lafon L Benzhydrylsulfinylacetamide derivatives published 28 January 1986 Cao J Prisinzano TE Okunola OM Kopajtic T Shook M Katz JL Newman AH October 2010 Structure Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil 2 diphenylmethyl sulfinyl acetamide Analogues ACS Medicinal Chemistry Letters 2 1 48 52 doi 10 1021 ml1002025 PMC 3041981 PMID 21344069 US 20130295196 Konofal E Lauflumide and the enantiomers thereof method for preparing same and therapeutic uses thereof published 7 November 2013 Flmodafinil Dosage How Much Should You Take and When modaforum org Retrieved 2023 09 26 Louis Lafon 18 December 1984 Patent US 4489095 A Halogenobenzhydrylsulfinylacetohydroxamic acids Retrieved 25 July 2015 Pipeline NLS Pharmaceuticals nbsp This drug article relating to the nervous system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CRL 40 940 amp oldid 1216731335, wikipedia, wiki, book, books, library,
