A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily killing them otherwise. Depending on their application, bacteriostatic antibiotics, disinfectants, antiseptics and preservatives can be distinguished. When bacteriostatic antimicrobials are used, the duration of therapy must be sufficient to allow host defense mechanisms to eradicate the bacteria. Upon removal of the bacteriostat, the bacteria usually start to grow rapidly. This is in contrast to bactericides, which kill bacteria.[1]
An illustration shows the different effects of the bacteriostatic agent and bactericidal agent
Bacteriostats are often used in plastics to prevent growth of bacteria on surfaces. Bacteriostats commonly used in laboratory work include sodium azide (which is acutely toxic) and thiomersal.
Bacteriostatic antibiotics limit the growth of bacteria by interfering with bacterial protein production, DNA replication, or other aspects of bacterial cellular metabolism. They must work together with the immune system to remove the microorganisms from the body. However, there is not always a precise distinction between them and bactericidal antibiotics; high concentrations of some bacteriostatic agents are also bactericidal, whereas low concentrations of some bactericidal agents are bacteriostatic. This group[2] includes:
^Pankey GA, Sabath LD (March 2004). "Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections". Clin. Infect. Dis. 38 (6): 864–70. doi:10.1086/381972. PMID 14999632.
^Shetty N, Aarons E, Andrews J (2009). "Chapter 5: General principles of antimicrobial therapy". In Andrews J, Shetty N, Tang JW (eds.). Infectious Disease: Pathogenesis, Prevention and Case Studies. Wiley-Blackwell. ISBN978-1-4051-3543-6.
bacteriostatic, agent, bacteriostatic, agent, bacteriostat, abbreviated, bstatic, biological, chemical, agent, that, stops, bacteria, from, reproducing, while, necessarily, killing, them, otherwise, depending, their, application, bacteriostatic, antibiotics, d. A bacteriostatic agent or bacteriostat abbreviated Bstatic is a biological or chemical agent that stops bacteria from reproducing while not necessarily killing them otherwise Depending on their application bacteriostatic antibiotics disinfectants antiseptics and preservatives can be distinguished When bacteriostatic antimicrobials are used the duration of therapy must be sufficient to allow host defense mechanisms to eradicate the bacteria Upon removal of the bacteriostat the bacteria usually start to grow rapidly This is in contrast to bactericides which kill bacteria 1 An illustration shows the different effects of the bacteriostatic agent and bactericidal agentBacteriostats are often used in plastics to prevent growth of bacteria on surfaces Bacteriostats commonly used in laboratory work include sodium azide which is acutely toxic and thiomersal Contents 1 Bacteriostatic antibiotics 2 See also 3 ReferencesBacteriostatic antibiotics editBacteriostatic antibiotics limit the growth of bacteria by interfering with bacterial protein production DNA replication or other aspects of bacterial cellular metabolism They must work together with the immune system to remove the microorganisms from the body However there is not always a precise distinction between them and bactericidal antibiotics high concentrations of some bacteriostatic agents are also bactericidal whereas low concentrations of some bactericidal agents are bacteriostatic This group 2 includes Chloramphenicol Clindamycin Ethambutol Lincosamides Macrolides Nitrofurantoin Novobiocin Oxazolidinone Spectinomycin Sulfonamides Tetracyclines Tigecycline TrimethoprimSee also editList of antibiotics Oligodynamic effectReferences edit Pankey GA Sabath LD March 2004 Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram positive bacterial infections Clin Infect Dis 38 6 864 70 doi 10 1086 381972 PMID 14999632 Shetty N Aarons E Andrews J 2009 Chapter 5 General principles of antimicrobial therapy In Andrews J Shetty N Tang JW eds Infectious Disease Pathogenesis Prevention and Case Studies Wiley Blackwell ISBN 978 1 4051 3543 6 nbsp This antiinfective drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Bacteriostatic agent amp oldid 1093955557, wikipedia, wiki, book, books, library,
