^Luther JM (September 2014). "Is there a new dawn for selective mineralocorticoid receptor antagonism?". Current Opinion in Nephrology and Hypertension. 23 (5): 456–61. doi:10.1097/MNH.0000000000000051. PMC4248353. PMID 24992570.
December 15, 2023
benidipine, dihydropyridine, calcium, channel, blocker, treatment, high, blood, pressure, hypertension, triple, type, calcium, channel, blocker, reno, cardioprotective, clinical, dataahfs, drugs, cominternational, drug, namesroutes, ofadministrationby, mouthat. Benidipine is a dihydropyridine calcium channel blocker for the treatment of high blood pressure hypertension It is a triple L T and N type calcium channel blocker It is reno and cardioprotective BenidipineClinical dataAHFS Drugs comInternational Drug NamesRoutes ofadministrationBy mouthATC codeC08CA15 WHO IdentifiersIUPAC name O5 methyl O3 3R 1 phenylmethyl piperidin 3 yl 2 6 dimethyl 4 3 nitrophenyl 1 4 dihydropyridine 3 5 dicarboxylateCAS Number105979 17 7 YPubChem CID656668ChemSpider571013 NUNII4G9T91JS7EChEMBLChEMBL2218858 NChemical and physical dataFormulaC 28H 31N 3O 6Molar mass505 571 g mol 13D model JSmol Interactive imageSMILES O N O c1cccc c1 C H 4C C O OC C N C C4 C O O C H 3CCCN Cc2ccccc2 C3 C CInChI InChI 1S C28H31N3O6 c1 18 24 27 32 36 3 26 21 11 7 12 22 15 21 31 34 35 25 19 2 29 18 28 33 37 23 13 8 14 30 17 23 16 20 9 5 4 6 10 20 h4 7 9 12 15 23 26 29H 8 13 14 16 17H2 1 3H3 t23 26 m1 s1 NKey QZVNQOLPLYWLHQ ZEQKJWHPSA N N N Y what is this verify It was patented in 1981 and approved for medical use in 1991 1 Contents 1 Dosing 2 Mechanism 3 Names 4 ReferencesDosing editBenidipine is dosed as 2 8 mg once daily 2 Mechanism editBenidipine is a calcium channel blocker Benidipine has additionally been found to act as an antagonist of the mineralocorticoid receptor or as an antimineralocorticoid 3 Names editOther names include Benidipinum or benidipine hydrochloride Benidipine is sold as Coniel by Kyowa Hakko Kogyo Benidipine is initially licensed for use in Japan and selected Southeast Asian countries and later in Turkey where it is sold as 4 mg tablets References edit Fischer J Ganellin CR 2006 Analogue based Drug Discovery John Wiley amp Sons p 465 ISBN 9783527607495 Hi Eisai Pharmaceutical Inc Coniel benidipine package insert Philippines MIMS Philippines CMPMedica Retrieved 2008 03 31 Luther JM September 2014 Is there a new dawn for selective mineralocorticoid receptor antagonism Current Opinion in Nephrology and Hypertension 23 5 456 61 doi 10 1097 MNH 0000000000000051 PMC 4248353 PMID 24992570 Retrieved from https en wikipedia org w index php title Benidipine amp oldid 1187573123, wikipedia, wiki, book, books, library,
