BT-20 is a breast cancercell line derived from a 74-year-old human female in 1958 by E.Y. Lasfargues and L. Ozzello.[1] The cells technically came from a triple-negative breast cancer, which was caused by an invasive ductal carcinoma in the mammary gland. BT-20 cells are known to have amplified regions of chromosomes 6, 11, and 20, with most cells being hyperdiploid.[2] The cells express an estrogen receptor with a deletion of exon 5, and are used in preclinical studies of breast cancer.
Referencesedit
^Lasfargues, EY; Ozzello, L (1958). "Cultivation of human breast carcinomas". Journal of the National Cancer Institute. 21 (6): 1131–1147. PMID 13611537.
tank, tank, breast, cancer, cell, line, derived, from, year, human, female, 1958, lasfargues, ozzello, cells, technically, came, from, triple, negative, breast, cancer, which, caused, invasive, ductal, carcinoma, mammary, gland, cells, known, have, amplified, . For the BT 20 tank see BT tank BT 20 is a breast cancer cell line derived from a 74 year old human female in 1958 by E Y Lasfargues and L Ozzello 1 The cells technically came from a triple negative breast cancer which was caused by an invasive ductal carcinoma in the mammary gland BT 20 cells are known to have amplified regions of chromosomes 6 11 and 20 with most cells being hyperdiploid 2 The cells express an estrogen receptor with a deletion of exon 5 and are used in preclinical studies of breast cancer References edit Lasfargues EY Ozzello L 1958 Cultivation of human breast carcinomas Journal of the National Cancer Institute 21 6 1131 1147 PMID 13611537 BT20 pawefish uk Retrieved 10 April 2018 External links editCellosaurus entry for BT 20 nbsp This oncology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title BT 20 amp oldid 1107982842, wikipedia, wiki, book, books, library,