AsponA is a small asRNA transcribed antisense to the penicillin-binding protein 1A gene called ponA. It was identified by RNAseq and the expression was validated by 5' and 3' RACE experiments in Pseudomanas aeruginosa. AsponA expression was up or down regulated under different antibiotic stress. Owing to its location it may be able to prevent the transcription or translation of the opposite gene.[1] Study by Wurtzel et al. and Ferrara et al. also detected its expression.[2][3]
^Gómez-Lozano M, Marvig RL, Tulstrup MV, Molin S (September 2014). "Expression of antisense small RNAs in response to stress in Pseudomonas aeruginosa". BMC Genomics. 15 (1): 783. doi:10.1186/1471-2164-15-783. PMC4180829. PMID 25213728.
^Wurtzel O, Yoder-Himes DR, Han K, Dandekar AA, Edelheit S, Greenberg EP, Sorek R, Lory S (September 2012). "The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature". PLOS Pathogens. 8 (9): e1002945. doi:10.1371/journal.ppat.1002945. PMC3460626. PMID 23028334.
^Ferrara S, Brugnoli M, De Bonis A, Righetti F, Delvillani F, Dehò G, Horner D, Briani F, Bertoni G (2012). "Comparative profiling of Pseudomonas aeruginosa strains reveals differential expression of novel unique and conserved small RNAs". PLOS ONE. 7 (5): e36553. Bibcode:2012PLoSO...736553F. doi:10.1371/journal.pone.0036553. PMC3349714. PMID 22590564.
January 01, 1970
aspona, antisense, aspona, small, asrna, transcribed, antisense, penicillin, binding, protein, gene, called, pona, identified, rnaseq, expression, validated, race, experiments, pseudomanas, aeruginosa, aspona, expression, down, regulated, under, different, ant. AsponA is a small asRNA transcribed antisense to the penicillin binding protein 1A gene called ponA It was identified by RNAseq and the expression was validated by 5 and 3 RACE experiments in Pseudomanas aeruginosa AsponA expression was up or down regulated under different antibiotic stress Owing to its location it may be able to prevent the transcription or translation of the opposite gene 1 Study by Wurtzel et al and Ferrara et al also detected its expression 2 3 AsponA antisense RNAPredicted secondary structure and sequence conservation of AsponA antisense RNAIdentifiersRfamRF02812Other dataDomain s BacteriaGOGO 0046677SOSO 0000077 SO 0000370PDB structuresPDBeSee also editNrsZ small RNA SrbA sRNA Pseudomonas sRNAReferences edit Gomez Lozano M Marvig RL Tulstrup MV Molin S September 2014 Expression of antisense small RNAs in response to stress in Pseudomonas aeruginosa BMC Genomics 15 1 783 doi 10 1186 1471 2164 15 783 PMC 4180829 PMID 25213728 Wurtzel O Yoder Himes DR Han K Dandekar AA Edelheit S Greenberg EP Sorek R Lory S September 2012 The single nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature PLOS Pathogens 8 9 e1002945 doi 10 1371 journal ppat 1002945 PMC 3460626 PMID 23028334 Ferrara S Brugnoli M De Bonis A Righetti F Delvillani F Deho G Horner D Briani F Bertoni G 2012 Comparative profiling of Pseudomonas aeruginosa strains reveals differential expression of novel unique and conserved small RNAs PLOS ONE 7 5 e36553 Bibcode 2012PLoSO 736553F doi 10 1371 journal pone 0036553 PMC 3349714 PMID 22590564 Retrieved from https en wikipedia org w index php title AsponA antisense RNA amp oldid 1187877376, wikipedia, wiki, book, books, library,
