Annual pharmaceutical drug sales

Annual Sales (USD Millions)

Medication	Trade name	Primary Indication	Company	2015	2014	2013	2012	2011	2010	2009	2008^[1]^[2]^[3]^[4]^[5]^[6]	2007^[7]^[8]^[9]^[10]^[11]^[12]	2006^[13]^[14]^[15]^[16]^[17]^[18]	2005^[19]^[20]^[21]^[22]^[23]	2004^[24]^[25]^[26]^[27]	2003^[28]^[29]^[30]^[31]	2002^[32]^[33]^[34]^[35]	2001^[36]	2000^[37]^[38]
atorvastatin	Lipitor	Reduction of LDL cholesterol	Pfizer								$12,401	$12,675	$12,886	$12,187	$10,862	$9,231	$7,972	$6,448	$5,028
sunitinib malate	Sutent	Advanced and/or metastatic renal cell carcinoma (mRCC) & refractory gastrointestinal stromal tumors (GIST)	Pfizer								$847	$581	$219
irinotecan	Camptosar	Metastatic colorectal cancer	Pfizer								$563	$969	$903	$910	$554	$299
bimatoprost	Lumigan	Open-angle glaucoma or ocular hypertension	Allergan								$426.2	$391.7	$327.5	$267.6	$232.9	$181.3	$123	$35.4
exemestane	Aromasin	Breast cancer	Pfizer								$465	$401	$320	$247	$143	$58
epirubicin	Ellence	Breast cancer	Pfizer										$312	$367	$344	$216
trastuzumab	Herceptin	HER2-positive metastatic breast cancer	Genentech								$1,382	$1,287	$1,234	$747.2	$483.2	$424.8	$385.2	$346.7	$276
gemcitabine	Gemzar	Ovarian cancer, non-small cell lung cancer (NSCLC), metastatic breast cancer (MBC), and pancreatic cancer	Eli Lilly & Co.								$1,719.8	$1,592.4	$1,408.1	$1,334.5	$1,214.4	$1,021.7	$875	$723	$559.3
bevacizumab	Avastin	Metastatic colorectal cancer, non-small cell lung cancer (NSCLC), renal cell carcinoma, HER2-negative breast cancer	Genentech								$2,686	$2,296	$1,746	$1,132	$554.6
erlotinib	Tarceva	Advanced (metastatic) non-small cell lung cancer (NSCLC)	Genentech								$457	$417	$402	$274.9	$13.3
brimonidine	Alphagan	Open-angle glaucoma or ocular hypertension	Allergan													$286.8	$248.5	$250.9
rituximab	Rituxan	Non-Hodgkin's lymphoma and rheumatoid arthritis	Genentech								$2,587	$2,285	$2,071	$1,831.4	$1,574	$1,360.2	$1,162.9	$818.6
ranibizumab	Lucentis	Age-related macular degeneration (AMD)	Genentech								$875	$815	$380
omalizumab	Xolair	Asthma	Genentech								$517	$472	$425	$320.6	$187.6	$25.1
somatropin	Nutropin	Growth hormone deficiency, chronic kidney disease	Genentech								$358	$371	$378	$370.5	$348.8	$319.5
dornase alfa	Pulmozyme	Cystic fibrosis (CF)	Genentech								$257	$223	$199	$186.5	$157.1	$143.7	$138.1	$123
efalizumab	Raptiva	Plaque psoriasis	Genentech								$108	$107	$90	$79.2	$52.4	$1.4
montelukast	Singulair	Asthma	Merck								$4,336.9	$4,266.3	$3,579	$2,975.6	$2,622
alendronate sodium	Fosamax	Postmenopausal osteoporosis	Merck								$1,552.7	$3,049	$3,134.4	$3,191.2	$3,159.7
sitagliptin	Januvia	Type 2 diabetes	Merck								$1,397.1	$667.5	$42.9
simvastatin	Zocor	Reduction of LDL cholesterol	Merck								$660.1	$876.5	$2,802.7	$4,381.7	$5,196.5
rizatriptan benzoate	Maxalt	Migraine pain	Merck								$529.2	$467.3	$406.4	$348.4	$309.9
finasteride	Propecia	Hair loss	Merck								$429.1	$405.4	$351.8	$291.9	$270.2
etoricoxib	Arcoxia	Osteoarthritis and rheumatoid arthritis	Merck								$377.3	$329.1	$265.4	$218.2
sitagliptin/metformin HCl	Janumet	Type 2 diabetes	Merck								$351.1	$86.4
finasteride	Proscar	Benign prostatic hyperplasia (enlarged prostate)	Merck								$323.5	$411	$618.5	$741.4	$733.1
aprepitant	Emend	Nausea and vomiting prevention caused by chemotherapy	Merck								$263.8	$204.2	$130.8	$87
olanzapine	Zyprexa	Schizophrenia	Eli Lilly & Co.								$4,696.1	$4,761	$4,363.6	$4,202.3	$4,419.8	$4,276.9	$3,689	$3,087	$2,349.5
duloxetine HCl	Cymbalta	Depression and generalized anxiety disorder	Eli Lilly & Co.								$2,697.1	$2,102.9	$1,316.4	$679.7	$93.9
insulin lispro	Humalog	Type 1 diabetes in adults	Eli Lilly & Co.								$1,735.8	$1,474.6	$1,299.5	$1,197.7	$1,101.6	$1,021.3	$834	$628	$350.2
pemetrexed	Alimta	Locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC)	Eli Lilly & Co.								$1,154.7	$854	$611.8	$463.2	$142.6
raloxifene HCl	Evista	Osteoporosis	Eli Lilly & Co.								$1,075.6	$1,090.7	$1,045.3	$1,036.1	$1,012.7	$922.1	$822	$665	$521.5
insulin isophane	Humulin	Diabetes	Eli Lilly & Co.								$1,063.2	$985.2	$925.3	$1,004.7	$997.7	$1,060.4	$1,004	$1,061	$1,114.5
teriparatide	Forteo	Osteoporosis	Eli Lilly & Co.								$778.7	$709.3	$594.3	$389.3	$238.6	$65.3
atomoxetine HCl	Strattera	Attention-deficit/hyperactivity disorder (ADHD)	Eli Lilly & Co.								$579.5	$569.4	$579	$552.1	$666.7	$370.3
timolol	Istalol	Open-angle glaucoma	Ista Pharmaceutical								$14.6	$11.3	$8.3	$2.6
bromfenac	Xibrom	Ocular inflammation	Ista Pharmaceutical								$63	$42.1	$20.2	$5.3
hyaluronidase	Vitrase	Spreading agent	Ista Pharmaceutica								$5.2	$5.2	$4.2	$2.5
rivaroxaban	Xarelto	Deep vein thrombosis	Johnson & Johnson^[39]	$1,868	$1,522	$864	$239	$25

Notes

1. [1], Genentech 2008 10-K.
2. [2], Pfizer 2008 10-K.
3. [3], Eli Lilly & Co. 2008 10-K.
4. [4], Allergan 2008 10-K.
5. [5], Merck 2008 10-K.
6. [6], Ista Pharmaceuticals 2008 10-K.
7. [7], Genentech 2007 10-K.
8. [8], Pfizer 2007 10-K.
9. [9], Eli Lilly & Co. 2007 10-K.
10. [10], Allergan 2007 10-K.
11. [11], Merck 2007 10-K.
12. [12], Ista Pharmaceuticals 2007 10-K.
13. [13], Genentech 2006 10-K.
14. [14], Pfizer 2006 10-K.
15. [15], Eli Lilly & Co. 2006 10-K.
16. [16], Allergan 2006 10-K.
17. [17], Merck 2006 10-K.
18. [18], Ista Pharmaceuticals 2006 10-K.
19. [19], Genentech 2005 10-K.
20. [20], Pfizer 2005 10-K.
21. [21], Eli Lilly & Co. 2005 10-K.
22. [22], Allergan 2005 10-K.
23. [23], Merck 2005 10-K.
24. [24], Genentech 2004 10-K.
25. [25], Pfizer 2004 10-K.
26. [26], Eli Lilly & Co. 2004 10-K.
27. [27], Allergan 2004 10-K.
28. [28], Genentech 2003 10-K.
29. [29], Pfizer 2003 10-K.
30. [30], Eli Lilly & Co. 2003 10-K.
31. [31], Allergan 2003 10-K.
32. [32], Genentech 2002 10-K.
33. [33], Pfizer 2002 10-K.
34. [34], Eli Lilly & Co. 2002 10-K.
35. [35], Allergan 2002 10-K.
36. [36], Pfizer 2001 10-K.
37. [37], Genentech 2000 10-K.
38. [38], Eli Lilly & Co. 2000 10-K.
39. . www.investor.jnj.com. Archived from the original on 2016-04-09. Retrieved 2016-03-25.