Ghosh is a professional in the fields of Neuroscience and Biotechnology. Prior to his current role as CEO of Unity Biotechnology,[2] he held senior positions at several renowned institutions and companies. Ghosh served on the faculty of Johns Hopkins School of Medicine and as Chair of Neurobiology at UCSD, where he made significant contributions in the field of Neuroscience. From 2011 to 2016, he served as the Global Head of Neuroscience Discovery at F. Hoffmann-La Roche.[3] Ghosh was founding CSO of E-Scape Bio from 2016 to 2017 and served as the Head of Research and Early Development at Biogen from 2017 to 2020.[4] He was appointed CEO of Unity Biotechnology in 2020.[2]
Anirvan Ghosh, born in 1964 in Bloomington, Indiana, spent his formative years in Kanpur, India.[5] After completing high school at Central School Kendriya Vidyalaya IIT Kanpur, he ventured to the United States to pursue his undergraduate education at the prestigious California Institute of Technology.[6] He graduated with a B.S. with honors in Physics from Caltech in 1985.
From 1985 to 1990, Ghosh pursued his graduate studies at Stanford University in the Neurosciences Graduate Program. Under the guidance of Carla J. Shatz, he discovered the critical role of subplate neurons in establishing connections in the mammalian brain.[7] In 1991, he obtained his Ph.D. in Neurobiology from Stanford University. Ghosh then undertook postdoctoral training at Harvard Medical School, working alongside Michael E. Greenberg. During this time, he explored the regulation of differentiation by extracellular signals and how calcium regulation of BDNF expression can affect neuronal survival.
In 1995, Ghosh joined the esteemed Department of Neuroscience at Johns Hopkins School of Medicine.[1] While at Johns Hopkins his laboratory cloned CREST as a calcium-regulated transcription factor and showed that it plays a critical role in brain development.[8] In 2003 he was recruited to UCSD as the Stephen KufflerProfessor and served as Chair of Neurobiology in the Division of Biological Sciences.
In 2011, Ghosh was recruited to Roche to serve as the Global Head of Neuroscience Discovery. [3] He subsequently served as Head of Research and Early Development at Biogen from 2017 to 2020.[4] Ghosh was appointed CEO of UNITY Biotechnology in 2020, a company focused on developing therapies to slow, halt, or reverse diseases of aging. [2]
Major Publicationsedit
Ghosh, A., A. Antonini, S.K. McConnell and C.J. Shatz (1990). Requirement for subplate neurons in the formation of thalamocortical connections. Nature 347: 179-181
Ghosh, A. and C.J. Shatz (1992). Involvement of subplate neurons in the formation of ocular dominance columns. Science 255:1441-1443.
Ghosh, A., J. Carnahan and M.E. Greenberg (1994). Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263:1618-1623.
Ghosh, A. and M.E. Greenberg (1995). Distinct roles for bFGF and NT3 in the regulation of cortical neurogenesis. Neuron 15:89-103.
Polleux, F., R.J. Giger, D.D. Ginty, A.L. Kolodkin, and A. Ghosh (1998). Patterning of cortical efferent projections by semaphorin-neuropilin interactions. Science 282:1904-1906.
Polleux, F., T. Morrow and A. Ghosh (2000). Semaphorin 3A is a chemoattractant for developing cortical dendrites. Nature 404:567-573.
Aizawa, H., Hu, S-C, Bobb, K., Balakrishnan, K., Ince, G., Gurevich, I., Cowan, M., and A. Ghosh (2004). Dendrite development regulated by CREST, a calcium-regulated transcription activator. Science 303:197-202.
Qiu, Z. and A. Ghosh (2008) A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression. Neuron 60:775-787.
Sylwestrak, E and A. Ghosh (2012) Elfn1 regulates target-specific release probability at CA1-interneuron synapses. Science 338:536-540.
Referencesedit
^ ab"Biosketch of Anirvan Ghosh 12-15-10" (PDF). The Ghosh Lab. Retrieved December 12, 2017.
^Ghosh, Anirvan (January 9, 2004). "Cloning of CREST". ScienceDaily.
External linksedit
Official page: Anirvan Ghosh, Professor of Biology, UCSD
The Ghosh Lab
Science Daily: Gene Essential For Development Of Normal Brain Connections Resulting From Sensory Input Discovered
Science: Dendrite Development Regulated by CREST, a Calcium-Regulated Transcriptional Activator
Johns Hopkins University Gazette: Heads up! The Brain Behind The Acclaim, by Michael Purdy
UNITY BIOTECHNOLOGY press release
February 19, 2024
anirvan, ghosh, this, biography, living, person, needs, additional, citations, verification, please, help, adding, reliable, sources, contentious, material, about, living, persons, that, unsourced, poorly, sourced, must, removed, immediately, from, article, ta. This biography of a living person needs additional citations for verification Please help by adding reliable sources Contentious material about living persons that is unsourced or poorly sourced must be removed immediately from the article and its talk page especially if potentially libelous Find sources Anirvan Ghosh news newspapers books scholar JSTOR January 2008 Learn how and when to remove this template message Anirvan Ghosh Bengali অন র ব ণ ঘ ষ is an American neuroscientist and Biotech executive 1 Anirvan GhoshBorn1964 age 59 60 Bloomington Indiana U S Alma materCaltech Stanford UniversityScientific careerFieldsNeuroscienceInstitutionsUniversity of California San DiegoJohns Hopkins School of MedicineHarvard MedicalStanford UniversityCalifornia Institute of TechnologyGhosh is a professional in the fields of Neuroscience and Biotechnology Prior to his current role as CEO of Unity Biotechnology 2 he held senior positions at several renowned institutions and companies Ghosh served on the faculty of Johns Hopkins School of Medicine and as Chair of Neurobiology at UCSD where he made significant contributions in the field of Neuroscience From 2011 to 2016 he served as the Global Head of Neuroscience Discovery at F Hoffmann La Roche 3 Ghosh was founding CSO of E Scape Bio from 2016 to 2017 and served as the Head of Research and Early Development at Biogen from 2017 to 2020 4 He was appointed CEO of Unity Biotechnology in 2020 2 Contents 1 Biography 2 Major Publications 3 References 4 External linksBiography editAnirvan Ghosh born in 1964 in Bloomington Indiana spent his formative years in Kanpur India 5 After completing high school at Central School Kendriya Vidyalaya IIT Kanpur he ventured to the United States to pursue his undergraduate education at the prestigious California Institute of Technology 6 He graduated with a B S with honors in Physics from Caltech in 1985 From 1985 to 1990 Ghosh pursued his graduate studies at Stanford University in the Neurosciences Graduate Program Under the guidance of Carla J Shatz he discovered the critical role of subplate neurons in establishing connections in the mammalian brain 7 In 1991 he obtained his Ph D in Neurobiology from Stanford University Ghosh then undertook postdoctoral training at Harvard Medical School working alongside Michael E Greenberg During this time he explored the regulation of differentiation by extracellular signals and how calcium regulation of BDNF expression can affect neuronal survival In 1995 Ghosh joined the esteemed Department of Neuroscience at Johns Hopkins School of Medicine 1 While at Johns Hopkins his laboratory cloned CREST as a calcium regulated transcription factor and showed that it plays a critical role in brain development 8 In 2003 he was recruited to UCSD as the Stephen Kuffler Professor and served as Chair of Neurobiology in the Division of Biological Sciences In 2011 Ghosh was recruited to Roche to serve as the Global Head of Neuroscience Discovery 3 He subsequently served as Head of Research and Early Development at Biogen from 2017 to 2020 4 Ghosh was appointed CEO of UNITY Biotechnology in 2020 a company focused on developing therapies to slow halt or reverse diseases of aging 2 Major Publications editGhosh A A Antonini S K McConnell and C J Shatz 1990 Requirement for subplate neurons in the formation of thalamocortical connections Nature 347 179 181 Ghosh A and C J Shatz 1992 Involvement of subplate neurons in the formation of ocular dominance columns Science 255 1441 1443 Ghosh A J Carnahan and M E Greenberg 1994 Requirement for BDNF in activity dependent survival of cortical neurons Science 263 1618 1623 Ghosh A and M E Greenberg 1995 Distinct roles for bFGF and NT3 in the regulation of cortical neurogenesis Neuron 15 89 103 Polleux F R J Giger D D Ginty A L Kolodkin and A Ghosh 1998 Patterning of cortical efferent projections by semaphorin neuropilin interactions Science 282 1904 1906 Polleux F T Morrow and A Ghosh 2000 Semaphorin 3A is a chemoattractant for developing cortical dendrites Nature 404 567 573 Aizawa H Hu S C Bobb K Balakrishnan K Ince G Gurevich I Cowan M and A Ghosh 2004 Dendrite development regulated by CREST a calcium regulated transcription activator Science 303 197 202 Qiu Z and A Ghosh 2008 A calcium dependent switch in a CREST BRG1 complex regulates activity dependent gene expression Neuron 60 775 787 Sylwestrak E and A Ghosh 2012 Elfn1 regulates target specific release probability at CA1 interneuron synapses Science 338 536 540 References edit a b Biosketch of Anirvan Ghosh 12 15 10 PDF The Ghosh Lab Retrieved December 12 2017 a b c UNITY BIOTECHNOLOGY APPOINTS ANIRVAN GHOSH PH D AS CHIEF EXECUTIVE OFFICER a b Anirvan Ghosh named Head of Discovery for Roche s CNS European Pharmaceutical Review 21 February 2011 Retrieved 11 December 2017 a b Biogen Appoints Anirvan Ghosh Senior Vice President Research and Early Development Biogen Media March 16 2017 Archived from the original on 19 June 2017 Retrieved 11 December 2017 Anirvan Ghosh Pew Oral History Anirvan Ghosh Pew Oral History Anirvan Ghosh Pew Oral History Ghosh Anirvan January 9 2004 Cloning of CREST ScienceDaily External links editOfficial page Anirvan Ghosh Professor of Biology UCSD The Ghosh Lab Science Daily Gene Essential For Development Of Normal Brain Connections Resulting From Sensory Input Discovered Science Dendrite Development Regulated by CREST a Calcium Regulated Transcriptional Activator Johns Hopkins University Gazette Heads up The Brain Behind The Acclaim by Michael Purdy Fundamental Neuroscience Elsevier Directory of Pew Scholars BIOGEN press release UNITY BIOTECHNOLOGY press release Retrieved from https en wikipedia org w index php title Anirvan Ghosh amp oldid 1185797650, wikipedia, wiki, book, books, library,
