Andrzej Viktor "Andrew" Schally (born 30 November 1926) is an American endocrinologist[1] of Polish[1][2][4] ancestry, who was a corecipient, with Roger Guillemin and Rosalyn Sussman Yalow, of the Nobel Prize in Physiology or Medicine.[2] This award recognized his research in the discovery that the hypothalamus controls hormone production and release by the pituitary gland, which controls the regulation of other hormones in the body.[5] Later in life, Schally utilized his knowledge of hypothalamic hormones to research possible methods for birth control and cancer treatment.
In September 1939, when Poland was attacked by Nazi Germany and the Soviet Union, Schally escaped with Poland's President Ignacy Mościcki, the prime minister and the whole cabinet to the neutral Romania, where they were interned[citation needed].
I was fortunate to survive the holocaust while living among the Jewish-Polish Community in Roumania. I used to speak Polish, Roumanian, Yiddish, Italian and some German and Russian, but I have almost completely forgotten them, and my French in which I used to excel is also now far from fluent.[2]
Immediately after the war, in 1945, Schally moved via Italy and France to the United Kingdom[2] where he changed his first name to Andrew.[6] Schally received his education in Scotland and England.[2] In 1952, he moved to Canada. He received his doctorate in endocrinology from McGill University in 1957.[2] That same year he left for a research career in the United States where he has worked principally at Tulane University.[2] Schally currently conducts research in endocrinology at the Miami Veteran's Administration Medical Center in Miami, Florida.[citation needed] A Canadian citizen when he left Canada, Schally became a naturalized citizen of the United States in 1962.[2] He was affiliated with the Baylor College of Medicine for some years in Houston, Texas.[2]
Schally developed a new realm of knowledge concerning the brain's control over the body chemistry. Schally explained in his 1977 Nobel Lecture that he, alongside his researchers, dissected 250,000 pig hypothalami in order to isolate 5 mg of the hormone thyrotropin-releasing hormone (TRH) to determine the molecular structure of the hormone.[7] His work also addressed birth control methods and the effects of growth hormones on the body. Together with Roger Guillemin he described the neurohormone gonadotropin-releasing hormone (GnRH) that controls follicle-stimulating hormone (FSH) and luteinizing hormone (LH), two hormones that are integral parts of reproduction and growth and development.
Recognized as a Fellow of the Kosciuszko Foundation of Eminent Scientists of Polish Origin and Ancestry.[8]
Schally was married to Margaret Rachel White (divorced), and Ana Maria de Medeiros-Comaru.[4]
Cancer researchEdit
In 1981 it was demonstrated that the gonadotropin-releasing hormone (GnRH) agonistic analogs that Schally had developed between the years of 1972-1978 inhibited the growth of prostate cancer in rats. Alongside Dr. George Tolis, Schally conducted the first clinical trial of GnRH for patients with advanced prostate cancer in 1982. This method is now the preferred treatment for advanced prostate carcinoma. About 70% of patients with prostate cancer receive an agonist as their primary method of treatment.[7] According to Schally, his treatment causes fewer side effects than radiation and chemotherapy.[7] The previous method of treatment, orchiectomy or the administration of estrogens, was based on the research of Charles Brenton Huggins.
In 2004, after the death of his wife due to thyroid cancer, Schally found comfort in continuing his research.[7]
^ abAleksandra Ziolkowska-Boehm. Love for Family, Friends, and Books. Rowman & Littlefield, 2015. p. 246. ISBN9780761865698
^ abcdSchally, Andrew (December 8, 1977). "ASPECTS OF HYPOTHALAMIC REGULATION OF THE PITUITARY GLAND WITH MAJOR EMPHASIS ON ITS IMPLICATIONS FOR THE CONTROL OF REPRODUCTIVE PROCESSES" (PDF). The Nobel Prize. Retrieved April 11, 2021.
^. Archived from the original on 2018-05-09. Retrieved 2017-09-18.
^"Van Meter Award". American Thyroid Association. Retrieved 2021-11-18.
andrew, schally, andrzej, viktor, andrew, schally, born, november, 1926, american, endocrinologist, polish, ancestry, corecipient, with, roger, guillemin, rosalyn, sussman, yalow, nobel, prize, physiology, medicine, this, award, recognized, research, discovery. Andrzej Viktor Andrew Schally born 30 November 1926 is an American endocrinologist 1 of Polish 1 2 4 ancestry who was a corecipient with Roger Guillemin and Rosalyn Sussman Yalow of the Nobel Prize in Physiology or Medicine 2 This award recognized his research in the discovery that the hypothalamus controls hormone production and release by the pituitary gland which controls the regulation of other hormones in the body 5 Later in life Schally utilized his knowledge of hypothalamic hormones to research possible methods for birth control and cancer treatment Andrew SchallyBornAndrzej Viktor Schally 1926 11 30 30 November 1926 age 96 Wilno PolandNationalityPolish 1 2 CanadianAmerican 3 EducationMcGill UniversityMedical careerProfessionMedicineInstitutionsBaylor College of Medicine Tulane University University of MiamiSub specialtiesEndocrinologyAwardsAlbert Lasker Award 1975 Nobel Prize in Physiology or Medicine 1977 Contents 1 Life and career 2 Cancer research 3 Awards and honors 4 References 5 External linksLife and career EditAndrzej Wiktor Schally 6 was born in Wilno in the Second Polish Republic 1 2 4 now Vilnius Lithuania the son of Brigadier General Kazimierz Schally who was chief of the cabinet of President Ignacy Moscicki of Poland and Maria nee Lacka In September 1939 when Poland was attacked by Nazi Germany and the Soviet Union Schally escaped with Poland s President Ignacy Moscicki the prime minister and the whole cabinet to the neutral Romania where they were interned citation needed I was fortunate to survive the holocaust while living among the Jewish Polish Community in Roumania I used to speak Polish Roumanian Yiddish Italian and some German and Russian but I have almost completely forgotten them and my French in which I used to excel is also now far from fluent 2 Immediately after the war in 1945 Schally moved via Italy and France to the United Kingdom 2 where he changed his first name to Andrew 6 Schally received his education in Scotland and England 2 In 1952 he moved to Canada He received his doctorate in endocrinology from McGill University in 1957 2 That same year he left for a research career in the United States where he has worked principally at Tulane University 2 Schally currently conducts research in endocrinology at the Miami Veteran s Administration Medical Center in Miami Florida citation needed A Canadian citizen when he left Canada Schally became a naturalized citizen of the United States in 1962 2 He was affiliated with the Baylor College of Medicine for some years in Houston Texas 2 Schally developed a new realm of knowledge concerning the brain s control over the body chemistry Schally explained in his 1977 Nobel Lecture that he alongside his researchers dissected 250 000 pig hypothalami in order to isolate 5 mg of the hormone thyrotropin releasing hormone TRH to determine the molecular structure of the hormone 7 His work also addressed birth control methods and the effects of growth hormones on the body Together with Roger Guillemin he described the neurohormone gonadotropin releasing hormone GnRH that controls follicle stimulating hormone FSH and luteinizing hormone LH two hormones that are integral parts of reproduction and growth and development Schally received an honoris causa doctors degree from the Jagiellonian University in Krakow Recognized as a Fellow of the Kosciuszko Foundation of Eminent Scientists of Polish Origin and Ancestry 8 Schally was married to Margaret Rachel White divorced and Ana Maria de Medeiros Comaru 4 Cancer research EditIn 1981 it was demonstrated that the gonadotropin releasing hormone GnRH agonistic analogs that Schally had developed between the years of 1972 1978 inhibited the growth of prostate cancer in rats Alongside Dr George Tolis Schally conducted the first clinical trial of GnRH for patients with advanced prostate cancer in 1982 This method is now the preferred treatment for advanced prostate carcinoma About 70 of patients with prostate cancer receive an agonist as their primary method of treatment 7 According to Schally his treatment causes fewer side effects than radiation and chemotherapy 7 The previous method of treatment orchiectomy or the administration of estrogens was based on the research of Charles Brenton Huggins In 2004 after the death of his wife due to thyroid cancer Schally found comfort in continuing his research 7 Awards and honors EditVan Meter Award of the American Thyroid Association 1969 9 Albert Lasker Award 1975 Nobel Prize in Physiology or Medicine 1977 Golden Plate Award of the American Academy of Achievement 1978 10 References Edit nbsp Scholia has an author profile for Andrew Schally a b c d Andrew V Schally Andrew V Schally Encyclopaedia Britannica a b c d e f g h i j k Andrew V Schally Autobiography www nobelprize org Archived from the original on 2006 08 14 Bernard S Schlessinger June H Schlessinger The who s who of Nobel Prize winners 1901 1995 Onyx Press 1996 p 372 a b c Andrew V Schally Biography 1926 Nobel laureate not one to rest on his laurels a b Aleksandra Ziolkowska Boehm Love for Family Friends and Books Rowman amp Littlefield 2015 p 246 ISBN 9780761865698 a b c d Schally Andrew December 8 1977 ASPECTS OF HYPOTHALAMIC REGULATION OF THE PITUITARY GLAND WITH MAJOR EMPHASIS ON ITS IMPLICATIONS FOR THE CONTROL OF REPRODUCTIVE PROCESSES PDF The Nobel Prize Retrieved April 11 2021 Kosciuszko Foundation American Center of Polish culture Eminent Scientists of Polish Origin and Ancestry Archived from the original on 2018 05 09 Retrieved 2017 09 18 Van Meter Award American Thyroid Association Retrieved 2021 11 18 Golden Plate Awardees of the American Academy of Achievement www achievement org American Academy of Achievement Aleksandra Ziolkowska Korzenie sa polskie The Roots Are Polish Warsaw 1992 ISBN 83 7066 406 7 Aleksandra Ziolkowska Boehm The Roots Are Polish Toronto 2004 ISBN 0 920517 05 6 Nicholas Wade The Nobel Duel Garden City Anchor Press Doubleday 1981 External links EditAndrew Schally on Nobelprize org nbsp Retrieved from https en wikipedia org w index php title Andrew Schally amp oldid 1177406842, wikipedia, wiki, book, books, library,
