^Sánchez C, Arnt J, Didriksen M, Dragsted N, Moltzen Lenz S, Matz J (June 1998). . Psychopharmacology. 137 (3): 233–240. doi:10.1007/s002130050615. PMID 9683000. S2CID 20740372. Archived from the original on 2000-10-02. Retrieved 2009-12-03.
^Sramek JJ, Forrest M, Mengel H, Jhee SS, Hourani J, Cutler NR (1998). "A bridging study of LU 25-109 in patients with probable Alzheimer's disease". Life Sciences. 62 (3): 195–202. doi:10.1016/S0024-3205(97)01087-4. PMID 9488097.
January 01, 1970
alvameline, receptor, agonist, receptor, antagonist, that, under, investigation, treatment, alzheimer, disease, produced, poor, results, clinical, trials, subsequently, discontinued, clinical, dataatc, codenoneidentifiersiupac, name, ethyltetrazol, methyl, dih. Alvameline Lu 25 109 is a M1 receptor agonist and M2 M3 receptor antagonist 1 that was under investigation for the treatment of Alzheimer s disease but produced poor results in clinical trials 2 and was subsequently discontinued AlvamelineClinical dataATC codeNoneIdentifiersIUPAC name 3 2 ethyltetrazol 5 yl 1 methyl 5 6 dihydro 2H pyridineCAS Number120241 31 8 YPubChem CID178030ChemSpider154980 YUNII4XFD7B36M6ChEMBLChEMBL131428 YCompTox Dashboard EPA DTXSID30152748Chemical and physical dataFormulaC 9H 15N 5Molar mass193 254 g mol 13D model JSmol Interactive imageSMILES n1nn nc1 C2 C CCN C C2 CCInChI InChI 1S C9H15N5 c1 3 14 11 9 10 12 14 8 5 4 6 13 2 7 8 h5H 3 4 6 7H2 1 2H3 YKey RNMOMKCRCIRYCZ UHFFFAOYSA N Y verify See also editMilameline Sabcomeline Tazomeline XanomelineReferences edit Sanchez C Arnt J Didriksen M Dragsted N Moltzen Lenz S Matz J June 1998 In vivo muscarinic cholinergic mediated effects of Lu 25 109 a M1 agonist and M2 M3 antagonist in vitro Psychopharmacology 137 3 233 240 doi 10 1007 s002130050615 PMID 9683000 S2CID 20740372 Archived from the original on 2000 10 02 Retrieved 2009 12 03 Sramek JJ Forrest M Mengel H Jhee SS Hourani J Cutler NR 1998 A bridging study of LU 25 109 in patients with probable Alzheimer s disease Life Sciences 62 3 195 202 doi 10 1016 S0024 3205 97 01087 4 PMID 9488097 Retrieved from https en wikipedia org w index php title Alvameline amp oldid 1217263858, wikipedia, wiki, book, books, library,
