Thus, the two substrates of this enzyme are an aliphatic nitrile (R-CN) and H2O, whereas its two products are a carboxylic acid (R-COOH) and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. This enzyme participates in styrene degradation.
Referencesedit
* Kobayashi M, Yanaka N, Nagasawa T, Yamada H (1992). "Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase, from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue". Biochemistry. 31 (37): 9000–7. doi:10.1021/bi00152a042. PMID 1390687.
Pace HC, Brenner C (2001). "The nitrilase superfamily: classification, structure and function". Genome Biol. 2 (1): REVIEWS0001. doi:10.1186/gb-2001-2-1-reviews0001. PMC150437. PMID 11380987.
aliphatic, nitrilase, enzymology, aliphatic, nitrilase, also, known, aliphatic, nitrile, aminohydrolase, enzyme, that, catalyzes, hydrolysis, nitriles, carboxylic, acids, aliphatic, nitrilaseidentifiersec, 7cas, 9024, 2databasesintenzintenz, viewbrendabrenda, . In enzymology an aliphatic nitrilase also known as aliphatic nitrile aminohydrolase EC 3 5 5 7 is an enzyme that catalyzes the hydrolysis of nitriles to carboxylic acids aliphatic nitrilaseIdentifiersEC no 3 5 5 7CAS no 9024 90 2DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins R CN 2 H2O displaystyle rightleftharpoons R COOH NH3Thus the two substrates of this enzyme are an aliphatic nitrile R CN and H2O whereas its two products are a carboxylic acid R COOH and NH3 This enzyme belongs to the family of hydrolases those acting on carbon nitrogen bonds other than peptide bonds specifically in nitriles This enzyme participates in styrene degradation References edit Kobayashi M Yanaka N Nagasawa T Yamada H 1992 Primary structure of an aliphatic nitrile degrading enzyme aliphatic nitrilase from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue Biochemistry 31 37 9000 7 doi 10 1021 bi00152a042 PMID 1390687 Pace HC Brenner C 2001 The nitrilase superfamily classification structure and function Genome Biol 2 1 REVIEWS0001 doi 10 1186 gb 2001 2 1 reviews0001 PMC 150437 PMID 11380987 Portal nbsp Biology This EC 3 5 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Aliphatic nitrilase amp oldid 1187736262, wikipedia, wiki, book, books, library,
