^ abcGRCh38: Ensembl release 89: ENSG00000172497 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021620 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Hunt MC, Yamada J, Maltais LJ, Wright MW, Podesta EJ, Alexson SE (Aug 2005). "A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases". J Lipid Res. 46 (9): 2029–32. doi:10.1194/jlr.E500003-JLR200. PMID 16103133.
^Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE (Aug 2006). "Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs". FASEB J. 20 (11): 1855–64. doi:10.1096/fj.06-6042com. PMID 16940157. S2CID 501610.
Human ACOT12 genome location and ACOT12 gene details page in the UCSC Genome Browser.
PDBe-KB provides an overview of all the structure information available in the PDB for Human Acetyl-coenzyme A thioesterase
Further readingedit
Suematsu N, Isohashi F (2007). "Molecular cloning and functional expression of human cytosolic acetyl-CoA hydrolase". Acta Biochim. Pol. 53 (3): 553–61. doi:10.18388/abp.2006_3327. PMID 16951743.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Suematsu N, Okamoto K, Isohashi F (2004). "Simple and unique purification by size-exclusion chromatography for an oligomeric enzyme, rat liver cytosolic acetyl-coenzyme A hydrolase". J. Chromatogr. B. 790 (1–2): 239–44. doi:10.1016/s1570-0232(03)00167-3. PMID 12767336.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Suematsu N, Okamoto K, Shibata K, et al. (2001). "Molecular cloning and functional expression of rat liver cytosolic acetyl-CoA hydrolase". Eur. J. Biochem. 268 (9): 2700–9. doi:10.1046/j.1432-1327.2001.02162.x. PMID 11322891.
April 11, 2024
acot12, acyl, coenzyme, thioesterase, star, related, lipid, transfer, protein, stard15, enzyme, that, humans, encoded, gene, protein, contains, star, related, lipid, transfer, domain, available, structurespdbortholog, search, pdbe, rcsblist, codes3b7k, 4mob, 4. Acyl coenzyme A thioesterase 12 or StAR related lipid transfer protein 15 STARD15 is an enzyme that in humans is encoded by the ACOT12 gene 5 6 7 The protein contains a StAR related lipid transfer domain ACOT12Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes3B7K 4MOB 4MOCIdentifiersAliasesACOT12 CACH 1 Cach STARD15 THEAL acyl CoA thioesterase 12External IDsOMIM 614315 MGI 1921406 HomoloGene 12540 GeneCards ACOT12Gene location Human Chr Chromosome 5 human 1 Band5q14 1Start81 329 996 bp 1 End81 394 179 bp 1 Gene location Mouse Chr Chromosome 13 mouse 2 Band13 13 C3Start91 889 631 bp 2 End91 934 267 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inright lobe of liverkidneyduodenumAchilles tendonstromal cell of endometriumhypothalamusmuscle tissuesural nerveplacentaamygdalaTop expressed inkidneyleft lobe of liverproximal tubulejejunumintestinal villusduodenumseminiferous tubuleskin of abdomensexually immature organismileumMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functioncarboxylic ester hydrolase activity ATP binding hydrolase activity lipid binding acetyl CoA hydrolase activity acyl CoA hydrolase activity fatty acyl CoA binding palmitoyl CoA hydrolase activity long chain fatty acyl CoA binding thiolester hydrolase activityCellular componentcytoplasm cytosolBiological processpyruvate metabolic process lipid metabolism acyl CoA metabolic process acetyl CoA metabolic process fatty acid metabolic process palmitic acid biosynthetic processSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez13452674156EnsemblENSG00000172497ENSMUSG00000021620UniProtQ8WYK0Q9DBK0RefSeq mRNA NM 130767NM 028790RefSeq protein NP 570123NP 083066Location UCSC Chr 5 81 33 81 39 MbChr 13 91 89 91 93 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000172497 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000021620 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Hunt MC Yamada J Maltais LJ Wright MW Podesta EJ Alexson SE Aug 2005 A revised nomenclature for mammalian acyl CoA thioesterases hydrolases J Lipid Res 46 9 2029 32 doi 10 1194 jlr E500003 JLR200 PMID 16103133 Hunt MC Rautanen A Westin MA Svensson LT Alexson SE Aug 2006 Analysis of the mouse and human acyl CoA thioesterase ACOT gene clusters shows that convergent functional evolution results in a reduced number of human peroxisomal ACOTs FASEB J 20 11 1855 64 doi 10 1096 fj 06 6042com PMID 16940157 S2CID 501610 Entrez Gene ACOT12 acyl CoA thioesterase 12 External links editHuman ACOT12 genome location and ACOT12 gene details page in the UCSC Genome Browser PDBe KB provides an overview of all the structure information available in the PDB for Human Acetyl coenzyme A thioesteraseFurther reading editSuematsu N Isohashi F 2007 Molecular cloning and functional expression of human cytosolic acetyl CoA hydrolase Acta Biochim Pol 53 3 553 61 doi 10 18388 abp 2006 3327 PMID 16951743 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Suematsu N Okamoto K Isohashi F 2004 Simple and unique purification by size exclusion chromatography for an oligomeric enzyme rat liver cytosolic acetyl coenzyme A hydrolase J Chromatogr B 790 1 2 239 44 doi 10 1016 s1570 0232 03 00167 3 PMID 12767336 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Suematsu N Okamoto K Shibata K et al 2001 Molecular cloning and functional expression of rat liver cytosolic acetyl CoA hydrolase Eur J Biochem 268 9 2700 9 doi 10 1046 j 1432 1327 2001 02162 x PMID 11322891 Retrieved from https en wikipedia org w index php title ACOT12 amp oldid 1205180731, wikipedia, wiki, book, books, library,
