9-Nor-9β-hydroxyhexahydrocannabinol (9-Nor-9beta-HHC, sometimes incorrectly confused with 11-nor-9β-hydroxyhexahydrocannabinol)[1],is a cannabinoid first discovered from early modifications to the structure of THC, in a search for the simplest compound that could still fulfill the binding requirements to produce cannabis-like activity.[2][3]
^Johnson MR, Althuis TH, Bindra JS, Harbert CA, Melvin LS, Milne GM (1980). Potent Analgetics Derived From 9-Nor-9β-Hydroxyhexahydrocannabinol. NIDA Research Monograph. Vol. 34. pp. 68−74.
^Melvin LS, Johnson MR (1987). "Relationships of Tricyclic and Nonclassical Bicyclic Cannabinoids". In Rapaka RS, Makriyannis A (eds.). Structure-activity Relationships of the Cannabinoids. NIDA Research Monograph. Vol. 79. pp. 31–47.
^Järbe TU, Hiltunen AJ, Lander N, Mechoulam R (August 1986). "Cannabimimetic activity (delta 1-THC cue) of cannabidiol monomethyl ether and two stereoisomeric hexahydrocannabinols in rats and pigeons". Pharmacology, Biochemistry, and Behavior. 25 (2): 393–9. doi:10.1016/0091-3057(86)90015-8. PMID 3020594. S2CID 28373651.
January 06, 2023
hydroxyhexahydrocannabinol, 9beta, sometimes, incorrectly, confused, with, hydroxyhexahydrocannabinol, cannabinoid, first, discovered, from, early, modifications, structure, search, simplest, compound, that, could, still, fulfill, binding, requirements, produc. 9 Nor 9b hydroxyhexahydrocannabinol 9 Nor 9beta HHC sometimes incorrectly confused with 11 nor 9b hydroxyhexahydrocannabinol 1 is a cannabinoid first discovered from early modifications to the structure of THC in a search for the simplest compound that could still fulfill the binding requirements to produce cannabis like activity 2 3 9 Nor 9b hydroxyhexahydrocannabinolIdentifiersIUPAC name 6 6 Dimethyl 3 pentyl 6a 7 8 9 10 10a hexahydrobenzo c chromene 1 9 diolCAS Number52171 85 4 YPubChem CID6452587ChemSpider23232433UNIINA3QQQ5D4SCompTox Dashboard EPA DTXSID30966529Chemical and physical dataFormulaC 20H 30O 3Molar mass318 457 g mol 13D model JSmol Interactive imageSMILES CCCCCc1cc c2c c1 OC C H 3 C H 2C C H CC3 O C C OInChI InChI 1S C20H30O3 c1 4 5 6 7 13 10 17 22 19 15 12 14 21 8 9 16 15 20 2 3 23 18 19 11 13 h10 11 14 16 21 22H 4 9 12H2 1 3H3 t14 15 16 m1 s1Key AAIHVZNCFQTVCA BZUAXINKSA N11 Hydroxyhexahydrocannabinol is the structurally related methylene homologue of 11 Nor 9b hydroxyhexahydrocannabinol that has been found as a minor active metabolite of tetrahydrocannabinol and also a metabolite of the trace cannabinoid hexahydrocannabinol 4 See also EditAM 2389 9 Hydroxyhexahydrocannabinol Hexahydrocannabinol 11 Hydroxyhexahydrocannabinol HU 243 NabiloneReferences Edit 9 Hydroxy 9 norhexahydrocannabinol Johnson MR Althuis TH Bindra JS Harbert CA Melvin LS Milne GM 1980 Potent Analgetics Derived From 9 Nor 9b Hydroxyhexahydrocannabinol NIDA Research Monograph Vol 34 pp 68 74 Melvin LS Johnson MR 1987 Relationships of Tricyclic and Nonclassical Bicyclic Cannabinoids In Rapaka RS Makriyannis A eds Structure activity Relationships of the Cannabinoids NIDA Research Monograph Vol 79 pp 31 47 Jarbe TU Hiltunen AJ Lander N Mechoulam R August 1986 Cannabimimetic activity delta 1 THC cue of cannabidiol monomethyl ether and two stereoisomeric hexahydrocannabinols in rats and pigeons Pharmacology Biochemistry and Behavior 25 2 393 9 doi 10 1016 0091 3057 86 90015 8 PMID 3020594 S2CID 28373651 Retrieved from https en wikipedia org w index php title 9 Nor 9b hydroxyhexahydrocannabinol amp oldid 1085862521, wikipedia, wiki, book, books, library,
