5F-AB-PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively.[3] Its metabolism has been described in literature.[4][5]
^WO 2009106980, Buchler I, Hayes M, Hegde S, Hockerman S, Jones D, Kortum S, Rico J, Tenbrink R, Wu KK, "Indazole derivatives", published 2009-09-03, assigned to Pfizer
^"5F-AB-PINACA". Cayman Chemical. Retrieved 5 July 2015.
^Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience. 6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112. PMID 26134475.
^Wohlfarth A, Castaneto MS, Zhu M, Pang S, Scheidweiler KB, Kronstrand R, Huestis MA (May 2015). "Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA". The AAPS Journal. 17 (3): 660–77. doi:10.1208/s12248-015-9721-0. PMC4406957. PMID 25721194.
^Jang M, Shin I, Kim J, Yang W (July 2015). "Simultaneous quantification of 37 synthetic cannabinoid metabolites in human urine by liquid chromatography-tandem mass spectrometry". Forensic Toxicology. 33 (2): 221–234. doi:10.1007/s11419-015-0265-x. S2CID 3038555.
^ (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
^"Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz - BtMG) Anlage II (zu § 1 Abs. 1) (verkehrsfähige, aber nicht verschreibungsfähige Betäubungsmittel)" (in German). Retrieved 5 July 2015.
^. Central Narcotics Bureau (CNB). 30 April 2015. Archived from the original on 15 July 2015. Retrieved 24 July 2015.
April 30, 2023
pinaca, confused, with, apinaca, indazole, based, synthetic, cannabinoid, that, derived, from, series, compounds, originally, developed, pfizer, 2009, analgesic, medication, been, sold, online, designer, drug, legal, statuslegal, statusca, schedule, anlage, au. Not to be confused with 5F APINACA 5F AB PINACA is an indazole based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication and has been sold online as a designer drug 1 2 5F AB PINACALegal statusLegal statusCA Schedule II DE Anlage II Authorized trade only not prescriptible UK Class B US Schedule I Illegal in China and SingaporeIdentifiersIUPAC name N 2S 1 Amino 3 methyl 1 oxobutan 2 yl 1 5 fluoropentyl indazole 3 carboxamideCAS Number1800101 60 3PubChem CID91936927ChemSpider29763723UNII3L83B2298VCompTox Dashboard EPA DTXSID401009970Chemical and physical dataFormulaC 18H 25F N 4O 2Molar mass348 422 g mol 13D model JSmol Interactive imageSMILES CC C C H NC O c1nn CCCCCF c2ccccc12 C N OInChI InChI 1S C18H25FN4O2 c1 12 2 15 17 20 24 21 18 25 16 13 8 4 5 9 14 13 23 22 16 11 7 3 6 10 19 h4 5 8 9 12 15H 3 6 7 10 11H2 1 2H3 H2 20 24 H 21 25 t15 m0 s1Key WCBYXIBEPFZUBG HNNXBMFYSA N5F AB PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0 48 nM and 2 6 nM respectively 3 Its metabolism has been described in literature 4 5 Contents 1 Legality 1 1 China 1 2 Germany 1 3 Singapore 2 See also 3 ReferencesLegality EditChina Edit As of October 2015 5F AB PINACA is a controlled substance in China 6 Germany Edit 5F AB PINACA is an Anlage II controlled substance in Germany as of May 2015 7 Singapore Edit It is also controlled under the Fifth Schedule of the Misuse of Drugs Act MDA in Singapore as of May 2015 8 See also Edit5F ADB 5F AMB 5F CUMYL PINACA AB FUBINACA AB CHFUPYCA AB PINACA ADB CHMINACA ADB FUBINACA ADB PINACA ADBICA APICA APINACA MDMB CHMICA PX 3References Edit WO 2009106980 Buchler I Hayes M Hegde S Hockerman S Jones D Kortum S Rico J Tenbrink R Wu KK Indazole derivatives published 2009 09 03 assigned to Pfizer 5F AB PINACA Cayman Chemical Retrieved 5 July 2015 Banister SD Moir M Stuart J Kevin RC Wood KE Longworth M et al September 2015 Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB FUBINACA ADB FUBINACA AB PINACA ADB PINACA 5F AB PINACA 5F ADB PINACA ADBICA and 5F ADBICA ACS Chemical Neuroscience 6 9 1546 59 doi 10 1021 acschemneuro 5b00112 PMID 26134475 Wohlfarth A Castaneto MS Zhu M Pang S Scheidweiler KB Kronstrand R Huestis MA May 2015 Pentylindole Pentylindazole Synthetic Cannabinoids and Their 5 Fluoro Analogs Produce Different Primary Metabolites Metabolite Profiling for AB PINACA and 5F AB PINACA The AAPS Journal 17 3 660 77 doi 10 1208 s12248 015 9721 0 PMC 4406957 PMID 25721194 Jang M Shin I Kim J Yang W July 2015 Simultaneous quantification of 37 synthetic cannabinoid metabolites in human urine by liquid chromatography tandem mass spectrometry Forensic Toxicology 33 2 221 234 doi 10 1007 s11419 015 0265 x S2CID 3038555 关于印发 非药用类麻醉药品和精神药品列管办法 的通知 in Chinese China Food and Drug Administration 27 September 2015 Archived from the original on 1 October 2015 Retrieved 1 October 2015 Gesetz uber den Verkehr mit Betaubungsmitteln Betaubungsmittelgesetz BtMG Anlage II zu 1 Abs 1 verkehrsfahige aber nicht verschreibungsfahige Betaubungsmittel in German Retrieved 5 July 2015 CNB NEWS RELEASE Central Narcotics Bureau CNB 30 April 2015 Archived from the original on 15 July 2015 Retrieved 24 July 2015 Retrieved from https en wikipedia org w index php title 5F AB PINACA amp oldid 1082420689, wikipedia, wiki, book, books, library,
