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4-Bromomethcathinone

4-Bromomethcathinone (4-BMC, Brephedrone) is a psychoactive drug and research chemical of the phenethylamine, amphetamine, and cathinone chemical classes. It acts as a serotonin and norepinephrine reuptake inhibitor,[1][2] but acts more like an antidepressant than a stimulant.[3] Some 4-halogenated cathinones seem to share the selective serotonergic neurotoxicity of their corresponding amphetamine analogues.[4]

4-Bromomethcathinone
Legal status
Legal status
  • BR: Class F2 (Prohibited psychotropics)
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class B
Identifiers
  • 1-(4-bromophenyl)-2-(methylamino)propan-1-one
CAS Number
  • 486459-03-4 Y
PubChem CID
  • 10421832
ChemSpider
  • 8597261 N
UNII
  • 9GU9FVS6HH
CompTox Dashboard (EPA)
  • DTXSID401014169
Chemical and physical data
FormulaC10H12BrNO
Molar mass242.116 g·mol−1
3D model (JSmol)
  • Interactive image
ChiralityRacemic mixture
  • CC(C(=O)C1=CC=C(C=C1)Br)NC
  • InChI=1S/C10H12BrNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3 N
  • Key:OOJXMFNDUXHDOV-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

Legal status Edit

As of October 2015, 4-BMC is a controlled substance in China.[5] 4-Bromomethcathinone is considered a Schedule 1 substance in Virginia.[6]

See also Edit

References Edit

  1. ^ Foley KF, Cozzi NV (1999). . Society for Neuroscience Abstracts. 25 (1–2): 1701. 678.17. Archived from the original on 2013-09-07. Retrieved 2013-07-28.
  2. ^ Foley KF, Cozzi NV (June 2002). "Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N-ethylmaleimide and protection by substrate analogs". Naunyn-Schmiedeberg's Archives of Pharmacology. 365 (6): 457–461. doi:10.1007/s00210-002-0532-3. PMID 12070759. S2CID 3244808.
  3. ^ Foley KF, Cozzi NV (2003). (PDF). Drug Development Research. 60 (4): 252–260. doi:10.1002/ddr.10297. S2CID 84128787. Archived from the original (PDF) on 2016-03-06. Retrieved 2015-09-09.
  4. ^ Wojcieszak J, Kuczyńska K, Zawilska JB (August 2020). "Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles". Neurotoxicity Research. 38 (2): 536–551. doi:10.1007/s12640-020-00227-8. PMC 7334283. PMID 32506339.
  5. ^ (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  6. ^ "18VAC110-20-322. Placement of Chemicals in Schedule I." Commonwealth of Virginia. 2 December 2015. Retrieved 11 March 2016.

bromomethcathinone, brephedrone, psychoactive, drug, research, chemical, phenethylamine, amphetamine, cathinone, chemical, classes, acts, serotonin, norepinephrine, reuptake, inhibitor, acts, more, like, antidepressant, than, stimulant, some, halogenated, cath. 4 Bromomethcathinone 4 BMC Brephedrone is a psychoactive drug and research chemical of the phenethylamine amphetamine and cathinone chemical classes It acts as a serotonin and norepinephrine reuptake inhibitor 1 2 but acts more like an antidepressant than a stimulant 3 Some 4 halogenated cathinones seem to share the selective serotonergic neurotoxicity of their corresponding amphetamine analogues 4 4 BromomethcathinoneLegal statusLegal statusBR Class F2 Prohibited psychotropics DE NpSG Industrial and scientific use only UK Class BIdentifiersIUPAC name 1 4 bromophenyl 2 methylamino propan 1 oneCAS Number486459 03 4 YPubChem CID10421832ChemSpider8597261 NUNII9GU9FVS6HHCompTox Dashboard EPA DTXSID401014169Chemical and physical dataFormulaC 10H 12Br N OMolar mass242 116 g mol 13D model JSmol Interactive imageChiralityRacemic mixtureSMILES CC C O C1 CC C C C1 Br NCInChI InChI 1S C10H12BrNO c1 7 12 2 10 13 8 3 5 9 11 6 4 8 h3 7 12H 1 2H3 NKey OOJXMFNDUXHDOV UHFFFAOYSA N N N Y what is this verify Legal status EditAs of October 2015 4 BMC is a controlled substance in China 5 4 Bromomethcathinone is considered a Schedule 1 substance in Virginia 6 See also Edit4B MAR 4 Chloromethcathinone 4 EthylmethcathinoneReferences Edit Foley KF Cozzi NV 1999 Bromine substitution at the ring 3 or 4 position of methcathinone enhances potency at serotonin uptake transporters Society for Neuroscience Abstracts 25 1 2 1701 678 17 Archived from the original on 2013 09 07 Retrieved 2013 07 28 Foley KF Cozzi NV June 2002 Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N ethylmaleimide and protection by substrate analogs Naunyn Schmiedeberg s Archives of Pharmacology 365 6 457 461 doi 10 1007 s00210 002 0532 3 PMID 12070759 S2CID 3244808 Foley KF Cozzi NV 2003 Novel aminopropiophenones as potential antidepressants PDF Drug Development Research 60 4 252 260 doi 10 1002 ddr 10297 S2CID 84128787 Archived from the original PDF on 2016 03 06 Retrieved 2015 09 09 Wojcieszak J Kuczynska K Zawilska JB August 2020 Four Synthetic Cathinones 3 Chloromethcathinone 4 Chloromethcathinone 4 Fluoro a Pyrrolidinopentiophenone and 4 Methoxy a Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles Neurotoxicity Research 38 2 536 551 doi 10 1007 s12640 020 00227 8 PMC 7334283 PMID 32506339 关于印发 非药用类麻醉药品和精神药品列管办法 的通知 in Chinese China Food and Drug Administration 27 September 2015 Archived from the original on 1 October 2015 Retrieved 1 October 2015 18VAC110 20 322 Placement of Chemicals in Schedule I Commonwealth of Virginia 2 December 2015 Retrieved 11 March 2016 nbsp This psychoactive drug related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 4 Bromomethcathinone amp oldid 1179247495, wikipedia, wiki, book, books, library,

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