This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating). This enzyme is also called 3-hydroxybenzoate 4-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation and 2,4-dichlorobenzoate degradation. It employs one cofactor, FAD.
Structural studiesedit
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2DKH and 2DKI.
hydroxybenzoate, monooxygenase, enzymology, enzyme, that, catalyzes, chemical, reactionidentifiersec, 23cas, 37256, 1databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, structuresrcsb, pdbe. In enzymology a 3 hydroxybenzoate 4 monooxygenase EC 1 14 13 23 is an enzyme that catalyzes the chemical reaction3 hydroxybenzoate 4 monooxygenaseIdentifiersEC no 1 14 13 23CAS no 37256 76 1DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins 3 hydroxybenzoate NADPH H O2 displaystyle rightleftharpoons 3 4 dihydroxybenzoate NADP H2O The 4 substrates of this enzyme are 3 hydroxybenzoate NADPH H and O2 whereas its 3 products are 3 4 dihydroxybenzoate NADP and H2O This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor and incorporation of one atom o oxygen into the other donor The systematic name of this enzyme class is 3 hydroxybenzoate NADPH oxygen oxidoreductase 4 hydroxylating This enzyme is also called 3 hydroxybenzoate 4 hydroxylase This enzyme participates in benzoate degradation via hydroxylation and 2 4 dichlorobenzoate degradation It employs one cofactor FAD Structural studies editAs of late 2007 two structures have been solved for this class of enzymes with PDB accession codes 2DKH and 2DKI References editMichalover JL Ribbons DW Hughes H 1973 3 Hydroxybenzoate 4 hydroxylase from Pseudomonas testosteroni Biochem Biophys Res Commun 55 3 888 96 doi 10 1016 0006 291X 73 91227 8 PMID 4148586 Premkumar R Rao PV Sreeleela NS Vaidyanathan CS 1969 m Hydroxybenzoic acid 4 hydroxylase from Aspergillus niger Can J Biochem 47 8 825 7 doi 10 1139 o69 129 PMID 4390252 Portal nbsp Biology This EC 1 14 13 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 3 hydroxybenzoate 4 monooxygenase amp oldid 1172335750, wikipedia, wiki, book, books, library,
