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The Michael J. Fox Foundation

The Michael J. Fox Foundation for Parkinson's Research is dedicated to finding a cure for Parkinson's disease (PD) established in 2000 by Michael J. Fox. It concentrates on funding research and ensuring the development of improved therapies for people with Parkinson's.

The Michael J. Fox Foundation for Parkinson's Research
AbbreviationMJFF
Founded31 October 2000; 22 years ago (2000-10-31)[1]
FounderMichael J. Fox
13-4141945[2]
Legal status501(c)(3) Non-profit
PurposeFunding research for better treatments and a cure for Parkinson's disease[2]
HeadquartersNew York City[2]
FieldsParkinson's disease clinical research
Skip Irving[3]
Deborah W. Brooks[2]
AffiliationsMJFF Canada[2]
Revenue (2015)
$98,886,808[4]
Expenses (2015)$96,607,583[4]
Employees (2014)
109[2]
Volunteers (2014)
17[2]
Websitewww.michaeljfox.org

History

Established in 2000 by Canadian actor Michael J. Fox,[5] the foundation has since become the largest non-profit funder of Parkinson's disease research in the world, with more than $1 billion of research projects to date.[6][7] In 2010, the Foundation launched the first large-scale clinical study on evolution biomarkers of the disease at a cost of $45 million over five years.[8]

Research funding

The Foundation works towards "translational" research—the work of translating basic scientific discoveries into simple treatments with definition to benefit the estimated five million people living with Parkinson's disease today.[9]

The Foundation drives progress by awarding grants to ensure that the most promising research avenues are thoroughly funded, explored and carried forward toward pharmacy shelves.[10] The Foundation's four annually recurring Pipeline Programs aim to speed research along the drug development pipeline.[11] The Pipeline Programs include:

Rapid Response Innovation Awards quickly support high-risk, high-reward projects with little to no existing preliminary data, but potential to significantly impact our understanding or treatment of PD (an Edmond J. Safra Core Program for PD Research).

Target Validation Awards provide support for work demonstrating whether modulation of a novel biological target has impact in a PD-relevant pre-clinical model — an essential step to the development of potential targeted therapies (an Edmond J. Safra Core Program for PD Research).

Clinical Intervention Awards support clinical testing of promising PD therapies that may significantly and fundamentally improve treatment of PD (an Edmond J. Safra Core Program for PD Research).

Therapeutics Development Initiative, an industry-exclusive support program for preclinical development of Parkinson's disease therapies with potential to fundamentally alter disease course and/or improve treatment of symptoms above and beyond current standards of care.

The Pipeline Programs are complemented by the Foundation's Critical Challenges in Parkinson's Disease program, which provides funds for top research priorities.[12] Critical Challenges in 2009/2010 include: speeding research on PD genetic targets, LRRK2 and alpha-synuclein; advancing research on neurotrophic factors; identifying biomarkers of PD; understanding patient's unmet needs, like postural instability and gait disturbances; and, promoting collaborations with the Arizona Parkinson's Disease Consortium.

Community and matchmaking

Education and awareness

The Michael J. Fox Foundation publishes a print newsletter The Fox Focus two times per year as well as a monthly e-newsletter, FoxFlash, to keep supporters updated on Parkinson's research progress.[14] In 2010, the Foundation launched an audio podcast series on Parkinson's science, hosted by KQED Public Radio Host David Iverson.[15] Living with Parkinson's is the Foundation's online source for information on PD (including an animation about how the brain is affected by Parkinson's), guides for the newly diagnosed and caregivers, stories from people living with the disease and additional resources.[16]

In 2016, it created a raffle to raise awareness for Parkinson's disease and raised $6.75 million through Nike and two auctions in foreign cities such as Hong Kong and London.[17] One of the Nike Mags sold for over $200,000.[18]

References

  1. ^ "The Michael J. Fox Foundation for Parkinson's Research". Division of Corporations. Delaware Department of State. Accessed on May 18, 2016.
  2. ^ a b c d e f g "Form 990: Return of Organization Exempt from Income Tax". The Michael J. Fox Foundation for Parkinson's Research. Guidestar. December 31, 2014.
  3. ^ "Skip Irving | Parkinson's Disease". www.michaeljfox.org. Retrieved 2022-12-26.
  4. ^ a b "The Michael J. Fox Foundation" (PDF). Foundation Center. Retrieved 16 November 2017.
  5. ^ "Names in the News". Associated Press. March 18, 2000. "My immediate plans are to spend time with my family and hang out. I'll be busy launching my Michael J. Fox Foundation for Parkinson's Research," he said. "I wanted to call it PD Cure but I bounced it off a friend and she said 'Pedicure.'"
  6. ^ The Michael J. Fox Foundation for Parkinson's Research
  7. ^ Malkin, Marc (2021-10-18). "Michael J. Fox on Raising $1 Billion to Help Find Parkinson's Cure: 'I Won't Stop Until It Happens'". Variety. Retrieved 2022-01-11.
  8. ^ "Michael J. Fox Foundation Launches $45M Parkinson Biomarker Initiative". 2012-09-28.
  9. ^ Our Research: The Michael J. Fox Foundation
  10. ^ Funding Opportunities: The Michael J. Fox Foundation
  11. ^ Pipeline Programs: The Michael J. Fox Foundation
  12. ^ Critical Challenges: The Michael J. Fox Foundation
  13. ^ Weiner, Michael W.; Nosheny, Rachel; Camacho, Monica; Truran-Sacrey, Diana; Mackin, R. Scott; Flenniken, Derek; Ulbricht, Aaron; Insel, Philip; Finley, Shannon; Fockler, Juliet; Veitch, Dallas (August 2018). "The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies". Alzheimer's & Dementia. 14 (8): 1063–1076. doi:10.1016/j.jalz.2018.02.021. ISSN 1552-5260. PMC 6126911. PMID 29754989.
  14. ^ Our Publications: The Michael J. Fox Foundation
  15. ^ Podcasts: The Michael J. Fox Foundation
  16. ^ Living with Parkinson's: The Michael J. Fox Foundation
  17. ^ Rooney, Kyle (21 October 2016). "The Michael J. Fox Foundation does raffle with Nike to raise awareness for Parkinson's disease". Hotnewhiphop. Retrieved 21 October 2016.
  18. ^ Rooney, Kyle (14 November 2016). "One pair of Nike Mags goes for over $ 200,000". Hotnewhiphop. Retrieved 14 November 2016.

External links

  • Official website

michael, foundation, foundation, redirects, here, terry, foundation, terry, this, article, multiple, issues, please, help, improve, discuss, these, issues, talk, page, learn, when, remove, these, template, messages, this, article, relies, excessively, referenc. Fox Foundation redirects here For the Terry Fox Foundation see Terry Fox Run This article has multiple issues Please help improve it or discuss these issues on the talk page Learn how and when to remove these template messages This article relies excessively on references to primary sources Please improve this article by adding secondary or tertiary sources Find sources The Michael J Fox Foundation news newspapers books scholar JSTOR August 2015 Learn how and when to remove this template message This article contains content that is written like an advertisement Please help improve it by removing promotional content and inappropriate external links and by adding encyclopedic content written from a neutral point of view November 2011 Learn how and when to remove this template message Learn how and when to remove this template message The Michael J Fox Foundation for Parkinson s Research is dedicated to finding a cure for Parkinson s disease PD established in 2000 by Michael J Fox It concentrates on funding research and ensuring the development of improved therapies for people with Parkinson s The Michael J Fox Foundation for Parkinson s ResearchAbbreviationMJFFFounded31 October 2000 22 years ago 2000 10 31 1 FounderMichael J FoxTax ID no 13 4141945 2 Legal status501 c 3 Non profitPurposeFunding research for better treatments and a cure for Parkinson s disease 2 HeadquartersNew York City 2 FieldsParkinson s disease clinical researchChairmanSkip Irving 3 Chief Executive OfficerDeborah W Brooks 2 AffiliationsMJFF Canada 2 Revenue 2015 98 886 808 4 Expenses 2015 96 607 583 4 Employees 2014 109 2 Volunteers 2014 17 2 Websitewww wbr michaeljfox wbr org Contents 1 History 2 Research funding 3 Community and matchmaking 4 Education and awareness 5 References 6 External linksHistory EditEstablished in 2000 by Canadian actor Michael J Fox 5 the foundation has since become the largest non profit funder of Parkinson s disease research in the world with more than 1 billion of research projects to date 6 7 In 2010 the Foundation launched the first large scale clinical study on evolution biomarkers of the disease at a cost of 45 million over five years 8 Research funding EditThe Foundation works towards translational research the work of translating basic scientific discoveries into simple treatments with definition to benefit the estimated five million people living with Parkinson s disease today 9 The Foundation drives progress by awarding grants to ensure that the most promising research avenues are thoroughly funded explored and carried forward toward pharmacy shelves 10 The Foundation s four annually recurring Pipeline Programs aim to speed research along the drug development pipeline 11 The Pipeline Programs include Rapid Response Innovation Awards quickly support high risk high reward projects with little to no existing preliminary data but potential to significantly impact our understanding or treatment of PD an Edmond J Safra Core Program for PD Research Target Validation Awards provide support for work demonstrating whether modulation of a novel biological target has impact in a PD relevant pre clinical model an essential step to the development of potential targeted therapies an Edmond J Safra Core Program for PD Research Clinical Intervention Awards support clinical testing of promising PD therapies that may significantly and fundamentally improve treatment of PD an Edmond J Safra Core Program for PD Research Therapeutics Development Initiative an industry exclusive support program for preclinical development of Parkinson s disease therapies with potential to fundamentally alter disease course and or improve treatment of symptoms above and beyond current standards of care The Pipeline Programs are complemented by the Foundation s Critical Challenges in Parkinson s Disease program which provides funds for top research priorities 12 Critical Challenges in 2009 2010 include speeding research on PD genetic targets LRRK2 and alpha synuclein advancing research on neurotrophic factors identifying biomarkers of PD understanding patient s unmet needs like postural instability and gait disturbances and promoting collaborations with the Arizona Parkinson s Disease Consortium Community and matchmaking EditTeam Fox for Parkinson s Research is the foundation s grassroots community project raising funds and awareness for Parkinson s disease The organization hosts the Fox Trial Finder which is a website for presenting clinical trials in Parkinson s disease clinical research 13 Education and awareness EditThe Michael J Fox Foundation publishes a print newsletter The Fox Focus two times per year as well as a monthly e newsletter FoxFlash to keep supporters updated on Parkinson s research progress 14 In 2010 the Foundation launched an audio podcast series on Parkinson s science hosted by KQED Public Radio Host David Iverson 15 Living with Parkinson s is the Foundation s online source for information on PD including an animation about how the brain is affected by Parkinson s guides for the newly diagnosed and caregivers stories from people living with the disease and additional resources 16 In 2016 it created a raffle to raise awareness for Parkinson s disease and raised 6 75 million through Nike and two auctions in foreign cities such as Hong Kong and London 17 One of the Nike Mags sold for over 200 000 18 References Edit The Michael J Fox Foundation for Parkinson s Research Division of Corporations Delaware Department of State Accessed on May 18 2016 a b c d e f g Form 990 Return of Organization Exempt from Income Tax The Michael J Fox Foundation for Parkinson s Research Guidestar December 31 2014 Skip Irving Parkinson s Disease www michaeljfox org Retrieved 2022 12 26 a b The Michael J Fox Foundation PDF Foundation Center Retrieved 16 November 2017 Names in the News Associated Press March 18 2000 My immediate plans are to spend time with my family and hang out I ll be busy launching my Michael J Fox Foundation for Parkinson s Research he said I wanted to call it PD Cure but I bounced it off a friend and she said Pedicure The Michael J Fox Foundation for Parkinson s Research Malkin Marc 2021 10 18 Michael J Fox on Raising 1 Billion to Help Find Parkinson s Cure I Won t Stop Until It Happens Variety Retrieved 2022 01 11 Michael J Fox Foundation Launches 45M Parkinson Biomarker Initiative 2012 09 28 Our Research The Michael J Fox Foundation Funding Opportunities The Michael J Fox Foundation Pipeline Programs The Michael J Fox Foundation Critical Challenges The Michael J Fox Foundation Weiner Michael W Nosheny Rachel Camacho Monica Truran Sacrey Diana Mackin R Scott Flenniken Derek Ulbricht Aaron Insel Philip Finley Shannon Fockler Juliet Veitch Dallas August 2018 The Brain Health Registry An internet based platform for recruitment assessment and longitudinal monitoring of participants for neuroscience studies Alzheimer s amp Dementia 14 8 1063 1076 doi 10 1016 j jalz 2018 02 021 ISSN 1552 5260 PMC 6126911 PMID 29754989 Our Publications The Michael J Fox Foundation Podcasts The Michael J Fox Foundation Living with Parkinson s The Michael J Fox Foundation Rooney Kyle 21 October 2016 The Michael J Fox Foundation does raffle with Nike to raise awareness for Parkinson s disease Hotnewhiphop Retrieved 21 October 2016 Rooney Kyle 14 November 2016 One pair of Nike Mags goes for over 200 000 Hotnewhiphop Retrieved 14 November 2016 External links EditOfficial website Retrieved from https en wikipedia org w index php title The Michael J Fox Foundation amp oldid 1129609406, wikipedia, wiki, book, books, library,

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