Although older sources state that Fusobacterium is part of the normal flora of the human oropharynx, the current consensus is that Fusobacterium should always be treated as a pathogen.[4]F. prausnitzii, a gut commensal associated with healthy patients, was completely reclassified as Faecalibacterium (Clostridiales:Ruminococcaceae) in 2002.
Fusobacterium is often associated with ulcerative colitis[citation needed]. Research of colon cancer has also shown an overrepresentation of Fusobacterium, both in feces of patients[5] and tumor issue itself[6][citation needed]. Whether Fusobacterium causes these diseases or only colonizes existing tumours, remains undetermined.[6]
The bacterium is a big anchor for biofilms.[7][8] It is usually susceptible to clindamycin,[9] while approximately 20% of the clinical strains are resistant to penicillin.[10] In contrast to Bacteroides spp., Fusobacterium has a potent lipopolysaccharide.
^Madigan M; Martinko J, eds. (2005). Brock Biology of Microorganisms (11th ed.). Prentice Hall. ISBN978-0-13-144329-7.
^Taber's Cyclopedic Medical Dictionary, 22nd Edition, ISBN9780803629790, (2009)n p.983
^Aliyu SH, Marriott RK, Curran MD, et al. (October 2004). "Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice". J Med Microbiol. 53 (Pt 10): 1029–35. doi:10.1099/jmm.0.45648-0. PMID 15358827.
^Ahn, J.; Sinha, R.; Pei, Z.; Dominianni, C.; Wu, J.; Shi, J.; Goedert, J. J.; Hayes, R. B.; Yang, L. (18 December 2013). "Human Gut Microbiome and Risk for Colorectal Cancer". J Natl Cancer Inst. 105 (24): 1907–1911. doi:10.1093/jnci/djt300. PMC3866154. PMID 24316595.
^ abAlice Park (18 October 2011). "A Surprising Link Between Bacteria and Colon Cancer". Time.com. Retrieved 18 October 2011.
^Saito, Y.; Fujii, R.; Nakagawa, K.-I.; Kuramitsu, H. K.; Okuda, K.; Ishihara, K. (February 2008). "Stimulation of Fusobacterium nucleatum biofilm formation by Porphyromonas gingivalis". Oral Microbiology and Immunology. 23 (1): 1–6. doi:10.1111/j.1399-302X.2007.00380.x. hdl:10130/821. PMID 18173791.
Anaerobic Gram-Negative Bacilli chapter in Baron's Medical Microbiology (online at the NCBI bookshelf).
Fusobacterium From MicrobeWiki, the student-edited microbiology resource
March 03, 2023
fusobacterium, genus, anaerobic, gram, negative, sporeforming, bacteria, belonging, gracilicutes, individual, cells, slender, shaped, bacilli, with, pointed, ends, strains, cause, several, human, diseases, including, periodontal, diseases, lemierre, syndrome, . Fusobacterium is a genus of anaerobic Gram negative non sporeforming bacteria belonging to Gracilicutes Individual cells are slender rod shaped bacilli with pointed ends 2 3 Strains of Fusobacterium cause several human diseases including periodontal diseases Lemierre s syndrome and topical skin ulcers FusobacteriumFusobacterium novum in liquid cultureScientific classificationDomain BacteriaPhylum FusobacteriotaClass FusobacteriiaOrder FusobacterialesFamily FusobacteriaceaeStaley and Whitman 2012Genus FusobacteriumKnorr 1922Type speciesFusobacterium nucleatumKnorr 1922Species 1 F animalis F canifelinum 1 F equinum 1 F gastrosuis F gonidiaformans 1 F hwasookii F massiliense F mortiferum 1 F naviforme 1 F necrogenes 1 F necrophorum 1 F nucleatum 1 F perfoetens 1 F periodonticum 1 F polymorphum 1 F pseudoperiodonticum Ca F pullicola F russii 1 F simiae 1 F ulcerans 1 F varium 1 F vincentii F watanabeiAlthough older sources state that Fusobacterium is part of the normal flora of the human oropharynx the current consensus is that Fusobacterium should always be treated as a pathogen 4 F prausnitzii a gut commensal associated with healthy patients was completely reclassified as Faecalibacterium Clostridiales Ruminococcaceae in 2002 Contents 1 Clinical relevance 2 Phylogeny 3 See also 4 References 5 External linksClinical relevance EditFusobacterium is often associated with ulcerative colitis citation needed Research of colon cancer has also shown an overrepresentation of Fusobacterium both in feces of patients 5 and tumor issue itself 6 citation needed Whether Fusobacterium causes these diseases or only colonizes existing tumours remains undetermined 6 The bacterium is a big anchor for biofilms 7 8 It is usually susceptible to clindamycin 9 while approximately 20 of the clinical strains are resistant to penicillin 10 In contrast to Bacteroides spp Fusobacterium has a potent lipopolysaccharide Phylogeny EditSee also Bacterial taxonomy 16S rRNA based LTP 12 2021 11 12 13 GTDB 07 RS207 by Genome Taxonomy Database 14 15 16 Fusobacterium F perfoetensF gonidiaformansF equinum Dorsch et al 2001F necrophorum F n funduliforme Halle 1898 ex Shinjo et al 1991F n necrophorum Flugge 1886 Shinjo et al 1991F ulceransF variumF mortiferumF necrogenesF gastrosuis De Witte et al 2017F russiiF periodonticumF polymorphumF naviforme Jungano 1909 Moore amp Holdeman 1970F vincentiiF canifelinumF nucleatumF simiae Slots and Potts 1982Filifactor alocis Cato et al 1985 Jalava and Eerola 1999F animalisF watanabei Tomida et al 2021 Fusobacterium perfoetens Tissier 1905 Moore and Holdeman 1973Cetobacterium Foster et al 1996Fusobacterium F ulcerans Adriaans and Shah 1988F varium Eggerth and Gagnon 1933 Moore and Holdeman 1969 Ca F pullicola Gilroy et al 2021F mortiferum Harris 1901 Moore and Holdeman 1970F necrogenes Weinberg et al 1937 Moore and Holdeman 1970F gonidiaformans Tunnicliff and Jackson 1925 Moore and Holdeman 1970F necrophorum Flugge 1886 Shinjo et al 1991F russii Hauduroy et al 1937 Moore and Holdeman 1970 F massiliense Mailhe et al 2017F periodonticum Slots et al 1984 F pseudoperiodonticum Park et al 2019F animalis Gharbia amp Shah 1992 Kook et al 2022F vincentii Dzink Sheenan amp Socransky 1990 Kook et al 2022F nucleatum Knorr 1922 type sp F canifelinum corrig Conrads et al 2004 F hwasookii Cho et al 2014F polymorphum Dzink Sheenan amp Socransky 1990 Kook et al 2022See also EditAltered Schaedler flora List of bacteria genera List of bacterial ordersReferences Edit a b c d e f g h i j k l m n o p Parte A C Fusobacterium LPSN Madigan M Martinko J eds 2005 Brock Biology of Microorganisms 11th ed Prentice Hall ISBN 978 0 13 144329 7 Taber s Cyclopedic Medical Dictionary 22nd Edition ISBN 9780803629790 2009 n p 983 Aliyu SH Marriott RK Curran MD et al October 2004 Real time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice J Med Microbiol 53 Pt 10 1029 35 doi 10 1099 jmm 0 45648 0 PMID 15358827 Ahn J Sinha R Pei Z Dominianni C Wu J Shi J Goedert J J Hayes R B Yang L 18 December 2013 Human Gut Microbiome and Risk for Colorectal Cancer J Natl Cancer Inst 105 24 1907 1911 doi 10 1093 jnci djt300 PMC 3866154 PMID 24316595 a b Alice Park 18 October 2011 A Surprising Link Between Bacteria and Colon Cancer Time com Retrieved 18 October 2011 Saito Y Fujii R Nakagawa K I Kuramitsu H K Okuda K Ishihara K February 2008 Stimulation of Fusobacterium nucleatum biofilm formation by Porphyromonas gingivalis Oral Microbiology and Immunology 23 1 1 6 doi 10 1111 j 1399 302X 2007 00380 x hdl 10130 821 PMID 18173791 Okuda Tamaki Kokubu Eitoyo Kawana Tomoko Saito Atsushi Okuda Katsuji Ishihara Kazuyuki Feb 2012 Synergy in biofilm formation between Fusobacterium nucleatum and Prevotella species PDF Anaerobe 18 1 110 116 doi 10 1016 j anaerobe 2011 09 003 hdl 10130 3922 ISSN 1095 8274 PMID 21945879 Clindamycin PDF Davis 2017 Archived from the original PDF on November 14 2017 Retrieved November 14 2017 Di Bella Stefano Antonello Roberta Maria Sanson Gianfranco Maraolo Alberto Enrico Giacobbe Daniele Roberto Sepulcri Chiara Ambretti Simone Aschbacher Richard Bartolini Laura Bernardo Mariano Bielli Alessandra June 2022 Anaerobic bloodstream infections in Italy ITANAEROBY A 5 year retrospective nationwide survey Anaerobe 75 102583 doi 10 1016 j anaerobe 2022 102583 PMID 35568274 S2CID 248736289 The LTP Retrieved 23 February 2021 LTP all tree in newick format Retrieved 23 February 2021 LTP 12 2021 Release Notes PDF Retrieved 23 February 2021 GTDB release 07 RS207 Genome Taxonomy Database Retrieved 20 June 2022 ar53 r207 sp label Genome Taxonomy Database Retrieved 20 June 2022 Taxon History Genome Taxonomy Database Retrieved 20 June 2022 External links EditAnaerobic Gram Negative Bacilli chapter in Baron s Medical Microbiology online at the NCBI bookshelf Fusobacterium From MicrobeWiki the student edited microbiology resource Retrieved from https en wikipedia org w index php title Fusobacterium amp oldid 1138894811, wikipedia, wiki, book, books, library,
