This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863.
zinc, finger, protein, protein, that, humans, encoded, znf197, gene, znf197identifiersaliasesznf197, d3s1363e, vhlak, zkscan9, znf166, znf20, zscan41, zinc, finger, protein, 197external, idsomim, 618359, homologene, 48487, genecards, znf197gene, location, huma. Zinc finger protein 197 is a protein that in humans is encoded by the ZNF197 gene 3 ZNF197IdentifiersAliasesZNF197 D3S1363E P18 VHLaK ZKSCAN9 ZNF166 ZNF20 ZSCAN41 zinc finger protein 197External IDsOMIM 618359 HomoloGene 48487 GeneCards ZNF197Gene location Human Chr Chromosome 3 human 1 Band3p21 31Start44 584 888 bp 1 End44 648 471 bp 1 RNA expression patternBgeeHumanMouse ortholog Top expressed inganglionic eminenceAchilles tendoncorpus callosumskeletal muscle tissueislet of Langerhansgastrocnemius muscleendometriumstromal cell of endometriumsmooth muscle tissuesural nerven aMore reference expression dataBioGPSn aGene ontologyMolecular functionDNA binding metal ion binding nucleic acid binding DNA binding transcription factor activity DNA binding transcription factor activity RNA polymerase II specificCellular componentnucleus intracellular anatomical structureBiological processtranscription DNA templated regulation of transcription DNA templated regulation of transcription by RNA polymerase IISources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez10168n aEnsemblENSG00000281709ENSG00000186448n aUniProtO14709n aRefSeq mRNA NM 001024855NM 001323293NM 001323294NM 001323295NM 001323296NM 006991n aRefSeq protein NP 001020026NP 001310222NP 001310223NP 001310224NP 001310225NP 008922n aLocation UCSC Chr 3 44 58 44 65 Mbn aPubMed search 2 n aWikidataView Edit HumanFunction editThis gene product belongs to the zinc finger protein superfamily members of which are regulatory proteins characterized by nucleic acid binding zinc finger domains The encoded protein contains 20 tandemly arrayed C2H2 type zinc fingers a Kruppel associated box KRAB domain and a SCAN box This transcript turns over rapidly and contains 3 UTR AUUUA motifs which are often a hallmark of rapid turnover It is overexpressed in some thyroid papillary carcinomas This gene is located in a cluster of zinc finger genes at 3p21 Naturally occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID 110354863 References edit a b c ENSG00000186448 GRCh38 Ensembl release 89 ENSG00000281709 ENSG00000186448 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene Zinc finger protein 197 Retrieved 2017 07 06 Further reading editThis article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on human chromosome 3 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Zinc finger protein 197 amp oldid 1167414618, wikipedia, wiki, book, books, library,
