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Winter (llama)

Winter (born 2015 or 2016) is a female llama who lives on a research farm near Ghent, Belgium and is notable for her role in award-winning research on the SARS-CoV2 virus.[1]

In 2016 Jason McLellan and Daniel Wrapp chose the nine-month-old Winter as the llama they would inject with stabilized spike proteins from SARS-CoV-1 and MERS-CoV viruses, hoping that she would produce antibodies or the smaller nanobodies to further their aim "to isolate a single antibody that could neutralize all coronaviruses".[1]

Camelids, including llamas, produce nanobodies, which are a form of antibody about half the size of human antibodies and are very stable and so can be easily manipulated.[2][3]

When the genetic sequence of SARS-CoV-2 was released in January 2020, scientists worked quickly to test whether any of the antibodies that they had previously isolated against the original SARS-CoV (taken from Winter) could also bind and neutralize SARS-CoV-2. They discovered that one of these nanobodies, which they had characterized using the Argonne National Laboratory's Advanced Photon Source, might be effective against SARS-CoV-2. This nanobody — called VHH72 — is now under development as a treatment for COVID-19. Jason McLellan and Daniel Wrapp received a 2020 Golden Goose Award for this research.[1][2]

As of 2021 Llama Winter lives at LABIOMISTA, the arts and culture park of artist Koen Vanmechelen in Genk, Limburg, Belgium, where people can visit and learn more about her.[4]

References edit

  1. ^ a b c Swenson, Haylie (December 2020). "2020 Golden Goose Award: A Llama Named Winter". American Association for the Advancement of Science. Retrieved 23 March 2023.
  2. ^ a b Andre Salle's (9 March 2021). "Why the lovable llama might be a secret weapon against COVID-19". Argonne National Laboratory.
  3. ^ Kramer, Jillian (6 May 2020). "Hoping Llamas Will Become Coronavirus Heroes". The New York Times – via NYTimes.com.
  4. ^ Vanmecheln, Kurt. "Winter's Kilobytes × we (Wk×W) | LABIOMISTA". www.labiomista.be. Retrieved 18 November 2021.

Further reading edit

  • "Belgian, U.S. scientists look to llama in search for COVID-19 treatment". Reuters. 5 May 2020.
  • Alex Robinson (5 May 2020), "Meet Winter, the Llama Who Might Just Save Us All From COVID-19", Modern Farmer
  • "Meet Winter, the 4-year-old llama whose blood might hold a treatment for COVID-19". Canadian Broadcasting Corporation. 11 May 2020.
  • "COVID-19 Researchers Study Llama's Special Antibodies". Morning Edition. NPR. 19 May 2020.
  • Dan Solomon (2 December 2020), "How a Llama and a University of Texas Lab Led to the Most Promising COVID-19 Treatment Yet – Researchers Daniel Wrapp and Jason McLellan owe a scientific honor they won this week to a Belgian camelid named Winter.", Texas Monthly
  • Marissa Parra (18 March 2021). "Llama Nanobodies Are At Center Of COVID-19 Treatment Study At Argonne National Laboratory". Chicago: WBBM-TV – via CBS Local.
  • Karin Brulliard; Carolyn Y. Johnson (6 May 2020). "The urgent quest for a coronavirus treatment involves door-to-door blood collection and a llama named Winter". The Washington Post.
  • Julie Mazziotta (7 May 2020), "A Llama Named Winter May Hold the Key to a Coronavirus Treatment – New research found that Winter the llama has antibodies that can neutralize the COVID-19 virus", People

  This article incorporates public domain material from Why the lovable llama might be a secret weapon against COVID-19. United States Department of Energy.

winter, llama, winter, born, 2015, 2016, female, llama, lives, research, farm, near, ghent, belgium, notable, role, award, winning, research, sars, cov2, virus, 2016, jason, mclellan, daniel, wrapp, chose, nine, month, winter, llama, they, would, inject, with,. Winter born 2015 or 2016 is a female llama who lives on a research farm near Ghent Belgium and is notable for her role in award winning research on the SARS CoV2 virus 1 In 2016 Jason McLellan and Daniel Wrapp chose the nine month old Winter as the llama they would inject with stabilized spike proteins from SARS CoV 1 and MERS CoV viruses hoping that she would produce antibodies or the smaller nanobodies to further their aim to isolate a single antibody that could neutralize all coronaviruses 1 Camelids including llamas produce nanobodies which are a form of antibody about half the size of human antibodies and are very stable and so can be easily manipulated 2 3 When the genetic sequence of SARS CoV 2 was released in January 2020 scientists worked quickly to test whether any of the antibodies that they had previously isolated against the original SARS CoV taken from Winter could also bind and neutralize SARS CoV 2 They discovered that one of these nanobodies which they had characterized using the Argonne National Laboratory s Advanced Photon Source might be effective against SARS CoV 2 This nanobody called VHH72 is now under development as a treatment for COVID 19 Jason McLellan and Daniel Wrapp received a 2020 Golden Goose Award for this research 1 2 As of 2021 update Llama Winter lives at LABIOMISTA the arts and culture park of artist Koen Vanmechelen in Genk Limburg Belgium where people can visit and learn more about her 4 References edit a b c Swenson Haylie December 2020 2020 Golden Goose Award A Llama Named Winter American Association for the Advancement of Science Retrieved 23 March 2023 a b Andre Salle s 9 March 2021 Why the lovable llama might be a secret weapon against COVID 19 Argonne National Laboratory Kramer Jillian 6 May 2020 Hoping Llamas Will Become Coronavirus Heroes The New York Times via NYTimes com Vanmecheln Kurt Winter s Kilobytes we Wk W LABIOMISTA www labiomista be Retrieved 18 November 2021 Further reading edit Belgian U S scientists look to llama in search for COVID 19 treatment Reuters 5 May 2020 Alex Robinson 5 May 2020 Meet Winter the Llama Who Might Just Save Us All From COVID 19 Modern Farmer Meet Winter the 4 year old llama whose blood might hold a treatment for COVID 19 Canadian Broadcasting Corporation 11 May 2020 COVID 19 Researchers Study Llama s Special Antibodies Morning Edition NPR 19 May 2020 Dan Solomon 2 December 2020 How a Llama and a University of Texas Lab Led to the Most Promising COVID 19 Treatment Yet Researchers Daniel Wrapp and Jason McLellan owe a scientific honor they won this week to a Belgian camelid named Winter Texas Monthly Marissa Parra 18 March 2021 Llama Nanobodies Are At Center Of COVID 19 Treatment Study At Argonne National Laboratory Chicago WBBM TV via CBS Local Karin Brulliard Carolyn Y Johnson 6 May 2020 The urgent quest for a coronavirus treatment involves door to door blood collection and a llama named Winter The Washington Post Julie Mazziotta 7 May 2020 A Llama Named Winter May Hold the Key to a Coronavirus Treatment New research found that Winter the llama has antibodies that can neutralize the COVID 19 virus People nbsp This article incorporates public domain material from Why the lovable llama might be a secret weapon against COVID 19 United States Department of Energy nbsp This article about an even toed ungulate is a stub You can help Wikipedia by expanding it vte nbsp This article about the COVID 19 pandemic is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Winter llama amp oldid 1181189427, wikipedia, wiki, book, books, library,

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