The uterotubal junction is the connection between the endometrial cavity of the uterus and the fallopian tube (uterine tube) at the proximal tubal opening, the beginning of the intramural part of the fallopian tube. Histologically, the endometrial epithelium changes over to ciliated tubal epithelium.
Functionedit
Patency of the uterotubal junction is necessary for normal reproduction. The tubes can get blocked here by infection (salpingitis) and surgical intervention may be necessary.
Mouse studies have indicated that selective passage of individual spermatozoa may occur at this junction,[1] with abnormal morphology being identified as a significant selection criterion, leading to predominantly normal sperm passing towards the ovum.[2] Absence of the protein calmegin has also been suggested as a critical factor for reliable sperm passage.[1]
Otheredit
The uterotubal junction is accessible by hysteroscopy and the entry point for tubal cannulation and falloposcopy. Contraceptive methods have been developed to block the uterotubal junction.
Referencesedit
^ abNakanishi, T.; Isotani, A.; Yamaguchi, R.; Ikawa, M.; Baba, T.; Suarez, S.; Okabe, M. (Sep 2004). "Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice" (Free full text). Biology of Reproduction. 71 (3): 959–965. doi:10.1095/biolreprod.104.028647. ISSN 0006-3363. PMID 15151931.
^Krzanowska, H (1974). "The Passage of Abnormal Spermatozoa Through the Uterotubal Junction of the Mouse". Reproduction. 38 (1): 81–90. doi:10.1530/jrf.0.0380081. PMID 4841384.
uterotubal, junction, uterotubal, junction, connection, between, endometrial, cavity, uterus, fallopian, tube, uterine, tube, proximal, tubal, opening, beginning, intramural, part, fallopian, tube, histologically, endometrial, epithelium, changes, over, ciliat. The uterotubal junction is the connection between the endometrial cavity of the uterus and the fallopian tube uterine tube at the proximal tubal opening the beginning of the intramural part of the fallopian tube Histologically the endometrial epithelium changes over to ciliated tubal epithelium Function editPatency of the uterotubal junction is necessary for normal reproduction The tubes can get blocked here by infection salpingitis and surgical intervention may be necessary Mouse studies have indicated that selective passage of individual spermatozoa may occur at this junction 1 with abnormal morphology being identified as a significant selection criterion leading to predominantly normal sperm passing towards the ovum 2 Absence of the protein calmegin has also been suggested as a critical factor for reliable sperm passage 1 Other editThe uterotubal junction is accessible by hysteroscopy and the entry point for tubal cannulation and falloposcopy Contraceptive methods have been developed to block the uterotubal junction References edit a b Nakanishi T Isotani A Yamaguchi R Ikawa M Baba T Suarez S Okabe M Sep 2004 Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin knockout and wild type male mice Free full text Biology of Reproduction 71 3 959 965 doi 10 1095 biolreprod 104 028647 ISSN 0006 3363 PMID 15151931 Krzanowska H 1974 The Passage of Abnormal Spermatozoa Through the Uterotubal Junction of the Mouse Reproduction 38 1 81 90 doi 10 1530 jrf 0 0380081 PMID 4841384 nbsp This human reproduction article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Uterotubal junction amp oldid 1111724549, wikipedia, wiki, book, books, library,
