Tyrode's solution is a solution that is roughly isotonic with interstitial fluid and used in physiological experiments and tissue culture. It resembles lactated Ringer's solution, but contains magnesium, a sugar (usually glucose) as an energy source and uses bicarbonate and phosphate as a buffer instead of lactate. Some variations also include phosphate and sulfate ions. It must be gassed with 95% oxygen and N2, 5% carbon dioxide when used for cell culture applications and physiology experiments in order to achieve an appropriate pH. With the addition of extra potassium salt, it can be used to prepare a cardioplegic solution.
Tyrode's solution was invented by Maurice Vejux Tyrode (1878–1930),[1] an American pharmacologist. The solution was a modification of Ringer-Locke's solution.
Therapyedit
Tyrode's solution is often used for irrigation of the peritoneum. It was also recommended by at least one physician as a dietary supplement, because of its inorganic salt content, as part of a medically-prescribed weight loss diet (minus the sugar content).[2]
^Llewellys F. Barker, "The Obesities -- Their Origins and Some of the Methods of Reducing Them." California and Western Medicine, August 1932; 37(2):78); print version of an "Address given under the auspices of the Scripps Metabolic Clinic at La Jolla, California, January 9, 1932.
^Thieme Chemistry, ed. (2009), RÖMPP Online - Version 3.7 (in German), Stuttgart: Georg Thieme Verlag KG
Tyrode M. (1910). "The Mode of Action of Some Purgative Salts". Arch Intern Phamacodyn. 17: 205–209.
May 13, 2024
tyrode, solution, this, article, needs, additional, citations, verification, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, books, scholar, jstor, november,. This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Tyrode s solution news newspapers books scholar JSTOR November 2008 Learn how and when to remove this message Tyrode s solution is a solution that is roughly isotonic with interstitial fluid and used in physiological experiments and tissue culture It resembles lactated Ringer s solution but contains magnesium a sugar usually glucose as an energy source and uses bicarbonate and phosphate as a buffer instead of lactate Some variations also include phosphate and sulfate ions It must be gassed with 95 oxygen and N2 5 carbon dioxide when used for cell culture applications and physiology experiments in order to achieve an appropriate pH With the addition of extra potassium salt it can be used to prepare a cardioplegic solution Contents 1 Development 2 Therapy 3 Composition 4 See also 5 ReferencesDevelopment editTyrode s solution was invented by Maurice Vejux Tyrode 1878 1930 1 an American pharmacologist The solution was a modification of Ringer Locke s solution Therapy editTyrode s solution is often used for irrigation of the peritoneum It was also recommended by at least one physician as a dietary supplement because of its inorganic salt content as part of a medically prescribed weight loss diet minus the sugar content 2 Composition editSubstance Concentration g L Molar concentration NaCl 8 00 134 mM KCl 0 20 2 68 mM CaCl2 0 20 1 80 mM MgCl2 0 10 1 05 mM NaH2PO4 0 05 417 mM NaHCO3 1 00 11 9 mM Glucose 1 00 5 56 mM pH 6 5 3 See also editLactated Ringer s solutionReferences edit Tyrode s solution www whonamedit com Llewellys F Barker The Obesities Their Origins and Some of the Methods of Reducing Them California and Western Medicine August 1932 37 2 78 print version of an Address given under the auspices of the Scripps Metabolic Clinic at La Jolla California January 9 1932 Thieme Chemistry ed 2009 ROMPP Online Version 3 7 in German Stuttgart Georg Thieme Verlag KG Tyrode M 1910 The Mode of Action of Some Purgative Salts Arch Intern Phamacodyn 17 205 209 Retrieved from https en wikipedia org w index php title Tyrode 27s solution amp oldid 1059475171, wikipedia, wiki, book, books, library,
