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Tuberculosis verrucosa cutis

Tuberculosis verrucosa cutis is a rash of small, red papules and nodules in the skin that may appear two to four weeks after inoculation by Mycobacterium tuberculosis in a previously infected and immunocompetent individual.[citation needed]

Tuberculosis verrucosa cutis
Other namesLupus verrucosus,[1] prosector's wart,[1] warty tuberculosis[1] anatomist's wart, verruca necrogenica
SpecialtyInfectious disease

It is also known as "prosector's wart" because it was a common occupational disease of prosectors, the preparers of dissections and autopsies. Reinfection by tuberculosis via the skin, therefore, can result from accidental exposure to human tuberculous tissue in physicians, pathologists and laboratory workers; or to tissues of other infected animals, in veterinarians, butchers, etc.

TVC is one of the many forms of cutaneous tuberculosis, such as the tuberculous chancre (which results from the cutaneous inoculation in immunocompetent people without previous exposure), and the reactivation cutaneous tuberculosis (the most common form, which appears in previously infected patients). Other forms of cutaneous tuberculosis are: lupus vulgaris, scrofuloderma, lichen scrofulosorum, erythema induratum and the papulonecrotic tuberculid.

It was described by René Laennec in 1826.[2]

Signs and symptoms edit

Because the TVC's entry point usually is the site of a trauma, wound or puncture in the skin (during an autopsy, for example), the most frequent site for the wart are the hands. But it can occur anywhere in the skin, such as in the sole of the feet, in the anus, and, in the case of children from developing countries, in the buttocks and knees. This is because children from countries of high incidence of tuberculosis can contract the lesion after contact with tuberculous sputum, by walking barefoot, sitting or playing on the ground.[citation needed]

When recent, the skin lesion has the outside appearance of a wart or verruca, thus it can be confused with other kinds of warts. It evolves to an annular red-brown plaque with time, with central healing and gradual expansion in the periphery. In this phase, it can be confused with fungal infections such as blastomycosis and chromoblastomycosis.[citation needed]

Cause edit

Diagnosis edit

The diagnosis is confirmed by a skin biopsy and a positive culture for acid-fast bacilli. A PPD test may also result positive.[citation needed]

Treatment edit

Therapy for cutaneous tuberculosis is the same as for systemic tuberculosis, and usually consists of a 4-drug regimen, i.e., isoniazid, rifampin, pyrazinamide, and ethambutol or streptomycin.[citation needed]

See also edit

Notes edit

  1. ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. Chapter 74. ISBN 978-1-4160-2999-1.
  2. ^ Tigoulet F, Fournier V, Caumes E (January 2003). "[Clinical forms of the cutaneous tuberculosis]". Bull Soc Pathol Exot (in French). 96 (5): 362–7. PMID 15015840.

References edit

Goldman, G.; Bolognia, J.L. Pinpointing cutaneous signs of tuberculosis: is it a common wart, or tuberculosis verrucosa cutis? 2004-11-16 at the Wayback Machine Journal of Critical Illness, Dec. 2002.

External links edit

  •   Media related to Tuberculosis verrucosa cutis at Wikimedia Commons
  • Cutaneous tuberculosis. eMedicine.

tuberculosis, verrucosa, cutis, rash, small, papules, nodules, skin, that, appear, four, weeks, after, inoculation, mycobacterium, tuberculosis, previously, infected, immunocompetent, individual, citation, needed, other, nameslupus, verrucosus, prosector, wart. Tuberculosis verrucosa cutis is a rash of small red papules and nodules in the skin that may appear two to four weeks after inoculation by Mycobacterium tuberculosis in a previously infected and immunocompetent individual citation needed Tuberculosis verrucosa cutisOther namesLupus verrucosus 1 prosector s wart 1 warty tuberculosis 1 anatomist s wart verruca necrogenicaSpecialtyInfectious disease It is also known as prosector s wart because it was a common occupational disease of prosectors the preparers of dissections and autopsies Reinfection by tuberculosis via the skin therefore can result from accidental exposure to human tuberculous tissue in physicians pathologists and laboratory workers or to tissues of other infected animals in veterinarians butchers etc TVC is one of the many forms of cutaneous tuberculosis such as the tuberculous chancre which results from the cutaneous inoculation in immunocompetent people without previous exposure and the reactivation cutaneous tuberculosis the most common form which appears in previously infected patients Other forms of cutaneous tuberculosis are lupus vulgaris scrofuloderma lichen scrofulosorum erythema induratum and the papulonecrotic tuberculid It was described by Rene Laennec in 1826 2 Contents 1 Signs and symptoms 2 Cause 3 Diagnosis 4 Treatment 5 See also 6 Notes 7 References 8 External linksSigns and symptoms editBecause the TVC s entry point usually is the site of a trauma wound or puncture in the skin during an autopsy for example the most frequent site for the wart are the hands But it can occur anywhere in the skin such as in the sole of the feet in the anus and in the case of children from developing countries in the buttocks and knees This is because children from countries of high incidence of tuberculosis can contract the lesion after contact with tuberculous sputum by walking barefoot sitting or playing on the ground citation needed When recent the skin lesion has the outside appearance of a wart or verruca thus it can be confused with other kinds of warts It evolves to an annular red brown plaque with time with central healing and gradual expansion in the periphery In this phase it can be confused with fungal infections such as blastomycosis and chromoblastomycosis citation needed Cause editThis section is empty You can help by adding to it May 2017 Diagnosis editThe diagnosis is confirmed by a skin biopsy and a positive culture for acid fast bacilli A PPD test may also result positive citation needed Treatment editTherapy for cutaneous tuberculosis is the same as for systemic tuberculosis and usually consists of a 4 drug regimen i e isoniazid rifampin pyrazinamide and ethambutol or streptomycin citation needed See also editTuberculosis Tuberculosis classification Tuberculosis diagnosis Tuberculosis treatment Prosector s paronychiaNotes edit a b c Rapini Ronald P Bolognia Jean L Jorizzo Joseph L 2007 Dermatology 2 Volume Set St Louis Mosby pp Chapter 74 ISBN 978 1 4160 2999 1 Tigoulet F Fournier V Caumes E January 2003 Clinical forms of the cutaneous tuberculosis Bull Soc Pathol Exot in French 96 5 362 7 PMID 15015840 References editGoldman G Bolognia J L Pinpointing cutaneous signs of tuberculosis is it a common wart or tuberculosis verrucosa cutis Archived 2004 11 16 at the Wayback Machine Journal of Critical Illness Dec 2002 External links edit nbsp Media related to Tuberculosis verrucosa cutis at Wikimedia Commons Cutaneous tuberculosis eMedicine Retrieved from https en wikipedia org w index php title Tuberculosis verrucosa cutis amp oldid 1167199763, wikipedia, wiki, book, books, library,

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