A traumatic neuroma is a type of neuroma which results from trauma to a nerve, usually during a surgical procedure. The most common oral locations are on the tongue and near the mental foramen of the mouth.[2] They are relatively rare on the head and neck.[3]
An essential step in the formation of a traumatic neuroma is injury to the perineurium. The perineum directs the growth of axons by acting as a surface that the axons cannot go through. If the perineurium is compromised, the axons may escape into the extraperineural space and arborize in an unregulated fashion.[4]
Preventionedit
Many surgeries have nerve injury as an unavoidable consequence such as limb amputation, nerve resections, or radical prostatectomy. Consequently, surgical techniques to reduce accidental nerve injury (nerve sparing techniques)[5][6] and reduce the likelihood to develop traumatic neuromas[7] have been researched. Targeted muscle reinnervation (TMR) is a promising technique used clinically that has significantly improved various benchmarks of quality of life such as pain free patients, residual limb pain, phantom limb pain, opioid use, and ambulation.[8] TMR involves the transfer of proximal nerve stumps to nearby muscle and was originally developed to improve prosthetic control. A newer, related technique is taking a muscle graft and moving it to the divided end of the peripheral nerve, called a regenerative peripheral nerve interface (RPNI). RPNI also significantly reduces the incidence of neuroma formation for amputation.[9]
^Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN978-1-4160-2999-1.
^Kahn, Michael A. Basic Oral and Maxillofacial Pathology. Volume 1. 2001.
^Lee EJ, Calcaterra TC, Zuckerbraun L (1998). "Traumatic neuromas of the head and neck". Ear, Nose, & Throat Journal. 77 (8): 670–4, 676. doi:10.1177/014556139807700816. PMID 9745184. S2CID 11599827.
^Zabaglo M, Dreyer MA. Neuroma. [Updated 2022 Nov 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK549838/#
^Michl U, Tennstedt P, Feldmeier L, Mandel P, Oh SJ, Ahyai S, Budäus L, Chun FKH, Haese A, Heinzer H, Salomon G, Schlomm T, Steuber T, Huland H, Graefen M, Tilki D. Nerve-sparing Surgery Technique, Not the Preservation of the Neurovascular Bundles, Leads to Improved Long-term Continence Rates After Radical Prostatectomy. Eur Urol. 2016 Apr;69(4):584-589. doi:10.1016/j.eururo.2015.07.037. Epub 2015 Aug 12. PMID: 26277303.
^Tavukçu HH, Aytac O, Atug F. Nerve-sparing techniques and results in robot-assisted radical prostatectomy. Investig Clin Urol. 2016 Dec;57(Suppl 2):S172-S184. doi:10.4111/icu.2016.57.S2.S172. Epub 2016 Dec 8. PMID: 27995221; PMCID: PMC5161020.
^Scott BB, Winograd JM, Redmond RW. Surgical Approaches for Prevention of Neuroma at Time of Peripheral Nerve Injury. Front Surg. 2022 Jun 27;9:819608. doi:10.3389/fsurg.2022.819608. PMID: 35832494; PMCID: PMC9271873.
^Chang BL, Mondshine J, Attinger CE, Kleiber GM. Targeted Muscle Reinnervation Improves Pain and Ambulation Outcomes in Highly Comorbid Amputees. Plast Reconstr Surg. 2021 Aug 1;148(2):376-386. doi:10.1097/PRS.0000000000008153. PMID: 34398088.
^Kubiak CA, Kemp SWP, Cederna PS, Kung TA. Prophylactic Regenerative Peripheral Nerve Interfaces to Prevent Postamputation Pain. Plast Reconstr Surg. 2019 Sep;144(3):421e-430e. doi:10.1097/PRS.0000000000005922. PMID: 31461024.
External linksedit
This article about a medical condition affecting the nervous system is a stub. You can help Wikipedia by expanding it.
traumatic, neuroma, traumatic, neuroma, type, neuroma, which, results, from, trauma, nerve, usually, during, surgical, procedure, most, common, oral, locations, tongue, near, mental, foramen, mouth, they, relatively, rare, head, neck, other, namesamputation, n. A traumatic neuroma is a type of neuroma which results from trauma to a nerve usually during a surgical procedure The most common oral locations are on the tongue and near the mental foramen of the mouth 2 They are relatively rare on the head and neck 3 Traumatic neuromaOther namesAmputation neuroma or Pseudoneuroma 1 SpecialtyNeurology Contents 1 Pathophysiology 2 Prevention 3 See also 4 References 5 External linksPathophysiology editAn essential step in the formation of a traumatic neuroma is injury to the perineurium The perineum directs the growth of axons by acting as a surface that the axons cannot go through If the perineurium is compromised the axons may escape into the extraperineural space and arborize in an unregulated fashion 4 Prevention editMany surgeries have nerve injury as an unavoidable consequence such as limb amputation nerve resections or radical prostatectomy Consequently surgical techniques to reduce accidental nerve injury nerve sparing techniques 5 6 and reduce the likelihood to develop traumatic neuromas 7 have been researched Targeted muscle reinnervation TMR is a promising technique used clinically that has significantly improved various benchmarks of quality of life such as pain free patients residual limb pain phantom limb pain opioid use and ambulation 8 TMR involves the transfer of proximal nerve stumps to nearby muscle and was originally developed to improve prosthetic control A newer related technique is taking a muscle graft and moving it to the divided end of the peripheral nerve called a regenerative peripheral nerve interface RPNI RPNI also significantly reduces the incidence of neuroma formation for amputation 9 See also editList of cutaneous conditionsReferences edit Rapini Ronald P Bolognia Jean L Jorizzo Joseph L 2007 Dermatology 2 Volume Set St Louis Mosby ISBN 978 1 4160 2999 1 Kahn Michael A Basic Oral and Maxillofacial Pathology Volume 1 2001 Lee EJ Calcaterra TC Zuckerbraun L 1998 Traumatic neuromas of the head and neck Ear Nose amp Throat Journal 77 8 670 4 676 doi 10 1177 014556139807700816 PMID 9745184 S2CID 11599827 Zabaglo M Dreyer MA Neuroma Updated 2022 Nov 30 In StatPearls Internet Treasure Island FL StatPearls Publishing 2023 Jan Available from https www ncbi nlm nih gov books NBK549838 Michl U Tennstedt P Feldmeier L Mandel P Oh SJ Ahyai S Budaus L Chun FKH Haese A Heinzer H Salomon G Schlomm T Steuber T Huland H Graefen M Tilki D Nerve sparing Surgery Technique Not the Preservation of the Neurovascular Bundles Leads to Improved Long term Continence Rates After Radical Prostatectomy Eur Urol 2016 Apr 69 4 584 589 doi 10 1016 j eururo 2015 07 037 Epub 2015 Aug 12 PMID 26277303 Tavukcu HH Aytac O Atug F Nerve sparing techniques and results in robot assisted radical prostatectomy Investig Clin Urol 2016 Dec 57 Suppl 2 S172 S184 doi 10 4111 icu 2016 57 S2 S172 Epub 2016 Dec 8 PMID 27995221 PMCID PMC5161020 Scott BB Winograd JM Redmond RW Surgical Approaches for Prevention of Neuroma at Time of Peripheral Nerve Injury Front Surg 2022 Jun 27 9 819608 doi 10 3389 fsurg 2022 819608 PMID 35832494 PMCID PMC9271873 Chang BL Mondshine J Attinger CE Kleiber GM Targeted Muscle Reinnervation Improves Pain and Ambulation Outcomes in Highly Comorbid Amputees Plast Reconstr Surg 2021 Aug 1 148 2 376 386 doi 10 1097 PRS 0000000000008153 PMID 34398088 Kubiak CA Kemp SWP Cederna PS Kung TA Prophylactic Regenerative Peripheral Nerve Interfaces to Prevent Postamputation Pain Plast Reconstr Surg 2019 Sep 144 3 421e 430e doi 10 1097 PRS 0000000000005922 PMID 31461024 External links edit nbsp This article about a medical condition affecting the nervous system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Traumatic neuroma amp oldid 1177992186, wikipedia, wiki, book, books, library,
