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Thomas Huckle Weller

Thomas Huckle Weller (June 15, 1915 – August 23, 2008) was an American virologist. He, John Franklin Enders and Frederick Chapman Robbins were awarded a Nobel Prize in Physiology or Medicine in 1954 for showing how to cultivate poliomyelitis viruses in a test tube, using a combination of human embryonic skin and muscle tissue.[1]

Thomas Huckle Weller
Born(1915-06-15)June 15, 1915
DiedAugust 23, 2008(2008-08-23) (aged 93)
NationalityAmerican
Alma materUniversity of Michigan, Harvard Medical School
Known forpoliomyelitis viruses
AwardsE. Mead Johnson Award (1953)
Nobel Prize in Physiology or Medicine (1954)
Scientific career
Fieldsvirology

Weller was born and grew up in Ann Arbor, Michigan, and then went to the University of Michigan, where his father Carl Vernon Weller was a professor in the Department of Pathology. At Michigan, he studied medical zoology and received a B.S. and an M.S., with his masters thesis on fish parasites. In 1936, Weller entered Harvard Medical School, and in 1939 began working under John Franklin Enders, with whom he would later (along with Frederick Chapman Robbins) share the Nobel Prize. It was Enders who got Weller involved in researching viruses and tissue-culture techniques for determining infectious disease causes. Weller received his MD in 1940, and went to work at Children's Hospital in Boston. In 1942, during World War II, he entered the Army Medical Corps and was stationed at the Antilles Medical Laboratory in Puerto Rico, earning the rank of Major and heading the facility's Departments of Bacteriology, Virology and Parasitology. After the War, he returned to Children's Hospital in Boston, and it was there in 1947, that he rejoined Enders in the newly created Research Division of Infectious Diseases. After several leading positions, in July 1954, he was appointed Tropical Public Health Department head at the Harvard School of Public Health. Weller also served from 1953 to 1959 as director of the Commission on Parasitic Diseases of the American Armed Forces Epidemiological Board. In 1954 he was awarded the George Ledlie prize in recognition of his research on rubella, polio and cytomegalovirus(CMV) viruses.

In addition to his research on polio, for which he won the Nobel Prize, Weller also contributed to treating schistosomiasis, and Coxsackie viruses. He was also the first to isolate the virus responsible for varicella.

In 1945, Weller married Kathleen Fahey, who died in 2011 aged 95. They had two sons and two daughters.

Citations Edit

  • Zetterström, Rolf; Lagercrantz, Hugo (2006), "J.F. Enders (1897-1985), T.H. Weller (1915-) and F.C. Robbins (1916-2003): a simplified method for the multiplication of poliomyelitis virus. Dreams of eradicating a terrifying disease.", Acta Paediatr. (published Sep 2006), vol. 95, no. 9, pp. 1026–8, doi:10.1080/08035250600900073, PMID 16938745, S2CID 30811791
  • Ligon, B Lee (2002), "Thomas Huckle Weller MD: Nobel Laureate and research pioneer in poliomyelitis, varicella-zoster virus, cytomegalovirus, rubella, and other infectious diseases.", Seminars in Pediatric Infectious Diseases (published Jan 2002), vol. 13, no. 1, pp. 55–63, doi:10.1053/spid.2002.31314, PMID 12118846
  • Kyle, R A; Shampo, M A (1997), "Thomas Huckle Weller and the successful culture of poliovirus.", Mayo Clin. Proc. (published May 1997), vol. 72, no. 5, p. 422, doi:10.1016/s0025-6196(11)64860-x, PMID 9146683
  • Bendiner, E (1982), "Enders, Weller, and Robbins: the trio that 'fished in troubled waters'.", Hosp. Pract. (Off. Ed.) (published Jan 1982), vol. 17, no. 1, pp. 163, 169, 174–5 passim, doi:10.1080/21548331.1982.11698030, PMID 6295913
  • Sulek, K (1968), "[Nobel prizes for John F. Enders, Frederick Ch, Robbins and Thomas H. Weller in 1954 for discovery of the possibility of growing poliomyelitis virus on various tissue media]", Wiad. Lek. (published Dec 15, 1968), vol. 21, no. 24, pp. 2301–3, PMID 4303387

References Edit

  1. ^ Thomas Weller, 93; Won Nobel Prize for Polio, Boston Globe, August 25, 2008

External links Edit

  • Thomas H. Weller on Nobelprize.org   including the Nobel Lecture, December 11, 1954 The Cultivation of the Poliomyelitis Viruses in Tissue Culture
  • Thomas Huckle Weller papers, 1896-2007 (inclusive), 1940-1990 (bulk). H MS c357. Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, Mass.

thomas, huckle, weller, june, 1915, august, 2008, american, virologist, john, franklin, enders, frederick, chapman, robbins, were, awarded, nobel, prize, physiology, medicine, 1954, showing, cultivate, poliomyelitis, viruses, test, tube, using, combination, hu. Thomas Huckle Weller June 15 1915 August 23 2008 was an American virologist He John Franklin Enders and Frederick Chapman Robbins were awarded a Nobel Prize in Physiology or Medicine in 1954 for showing how to cultivate poliomyelitis viruses in a test tube using a combination of human embryonic skin and muscle tissue 1 Thomas Huckle WellerBorn 1915 06 15 June 15 1915Ann Arbor MichiganDiedAugust 23 2008 2008 08 23 aged 93 Needham MassachusettsNationalityAmericanAlma materUniversity of Michigan Harvard Medical SchoolKnown forpoliomyelitis virusesAwardsE Mead Johnson Award 1953 Nobel Prize in Physiology or Medicine 1954 Scientific careerFieldsvirologyWeller was born and grew up in Ann Arbor Michigan and then went to the University of Michigan where his father Carl Vernon Weller was a professor in the Department of Pathology At Michigan he studied medical zoology and received a B S and an M S with his masters thesis on fish parasites In 1936 Weller entered Harvard Medical School and in 1939 began working under John Franklin Enders with whom he would later along with Frederick Chapman Robbins share the Nobel Prize It was Enders who got Weller involved in researching viruses and tissue culture techniques for determining infectious disease causes Weller received his MD in 1940 and went to work at Children s Hospital in Boston In 1942 during World War II he entered the Army Medical Corps and was stationed at the Antilles Medical Laboratory in Puerto Rico earning the rank of Major and heading the facility s Departments of Bacteriology Virology and Parasitology After the War he returned to Children s Hospital in Boston and it was there in 1947 that he rejoined Enders in the newly created Research Division of Infectious Diseases After several leading positions in July 1954 he was appointed Tropical Public Health Department head at the Harvard School of Public Health Weller also served from 1953 to 1959 as director of the Commission on Parasitic Diseases of the American Armed Forces Epidemiological Board In 1954 he was awarded the George Ledlie prize in recognition of his research on rubella polio and cytomegalovirus CMV viruses In addition to his research on polio for which he won the Nobel Prize Weller also contributed to treating schistosomiasis and Coxsackie viruses He was also the first to isolate the virus responsible for varicella In 1945 Weller married Kathleen Fahey who died in 2011 aged 95 They had two sons and two daughters Citations EditZetterstrom Rolf Lagercrantz Hugo 2006 J F Enders 1897 1985 T H Weller 1915 and F C Robbins 1916 2003 a simplified method for the multiplication of poliomyelitis virus Dreams of eradicating a terrifying disease Acta Paediatr published Sep 2006 vol 95 no 9 pp 1026 8 doi 10 1080 08035250600900073 PMID 16938745 S2CID 30811791 Ligon B Lee 2002 Thomas Huckle Weller MD Nobel Laureate and research pioneer in poliomyelitis varicella zoster virus cytomegalovirus rubella and other infectious diseases Seminars in Pediatric Infectious Diseases published Jan 2002 vol 13 no 1 pp 55 63 doi 10 1053 spid 2002 31314 PMID 12118846 Kyle R A Shampo M A 1997 Thomas Huckle Weller and the successful culture of poliovirus Mayo Clin Proc published May 1997 vol 72 no 5 p 422 doi 10 1016 s0025 6196 11 64860 x PMID 9146683 Bendiner E 1982 Enders Weller and Robbins the trio that fished in troubled waters Hosp Pract Off Ed published Jan 1982 vol 17 no 1 pp 163 169 174 5 passim doi 10 1080 21548331 1982 11698030 PMID 6295913 Sulek K 1968 Nobel prizes for John F Enders Frederick Ch Robbins and Thomas H Weller in 1954 for discovery of the possibility of growing poliomyelitis virus on various tissue media Wiad Lek published Dec 15 1968 vol 21 no 24 pp 2301 3 PMID 4303387References Edit Thomas Weller 93 Won Nobel Prize for Polio Boston Globe August 25 2008External links EditThomas H Weller on Nobelprize org nbsp including the Nobel Lecture December 11 1954 The Cultivation of the Poliomyelitis Viruses in Tissue Culture Thomas Huckle Weller papers 1896 2007 inclusive 1940 1990 bulk H MS c357 Harvard Medical Library Francis A Countway Library of Medicine Boston Mass Retrieved from https en wikipedia org w index php title Thomas Huckle Weller amp oldid 1159492822, wikipedia, wiki, book, books, library,

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