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Tandem repeat locus

Variable number of tandem repeat locus (VNTR locus) is any DNA sequence that exist in multiple copies strung together in a variety of tandem lengths.[1] The number of repeat copies present at a locus can be visualized by means of a Multi-locus or Multiple Loci VNTR Analysis (MLVA). In short, oligonucleotide primers are developed for each specific tandem repeat locus, followed by PCR and agarose gel electrophoresis. When the length of the repeat and the size of the flanking regions is known, the number of repeats can be calculated. Analysis of multiple loci will result in a genotype.[2]

References edit

  1. ^ Vergnaud G, Pourcel C (26 July 2018). "Multiple locus variable number of tandem repeats analysis". Molecular Epidemiology of Microorganisms. Methods in Molecular Biology. Vol. 551. pp. 141–58. doi:10.1007/978-1-60327-999-4_12. ISBN 978-1-60327-998-7. PMID 19521873.
  2. ^ Pöltl R, Luckenbach C, Ritter H (July 1998). "The short tandem repeat locus D3S1359". Forensic Science International. 95 (2): 163–8. doi:10.1016/S0379-0738(98)00087-5. PMID 9722977.


tandem, repeat, locus, this, article, technical, most, readers, understand, please, help, improve, make, understandable, experts, without, removing, technical, details, march, 2022, learn, when, remove, this, message, variable, number, tandem, repeat, locus, v. This article may be too technical for most readers to understand Please help improve it to make it understandable to non experts without removing the technical details March 2022 Learn how and when to remove this message Variable number of tandem repeat locus VNTR locus is any DNA sequence that exist in multiple copies strung together in a variety of tandem lengths 1 The number of repeat copies present at a locus can be visualized by means of a Multi locus or Multiple Loci VNTR Analysis MLVA In short oligonucleotide primers are developed for each specific tandem repeat locus followed by PCR and agarose gel electrophoresis When the length of the repeat and the size of the flanking regions is known the number of repeats can be calculated Analysis of multiple loci will result in a genotype 2 References edit Vergnaud G Pourcel C 26 July 2018 Multiple locus variable number of tandem repeats analysis Molecular Epidemiology of Microorganisms Methods in Molecular Biology Vol 551 pp 141 58 doi 10 1007 978 1 60327 999 4 12 ISBN 978 1 60327 998 7 PMID 19521873 Poltl R Luckenbach C Ritter H July 1998 The short tandem repeat locus D3S1359 Forensic Science International 95 2 163 8 doi 10 1016 S0379 0738 98 00087 5 PMID 9722977 nbsp This genetics article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Tandem repeat locus amp oldid 1123484581, wikipedia, wiki, book, books, library,

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