TRNA (guanine10-N2)-dimethyltransferase (EC 2.1.1.213, PAB1283, N(2),N(2)-dimethylguanosine tRNA methyltransferase, Trm-G10, PabTrm-G10, PabTrm-m2 2G10 enzyme) is an enzyme with systematic nameS-adenosyl-L-methionine:tRNA (guanine10-N2)-dimethyltransferase.[1] This enzyme catalyses the following chemical reaction
2 S-adenosyl-L-methionine + guanine10 in tRNA 2 S-adenosyl-L-homocysteine + N2-dimethylguanine10 in tRNA (overall reaction)
(1a) S-adenosyl-L-methionine + guanine10 in tRNA S-adenosyl-L-homocysteine + N2-methylguanine10 in tRNA
(1b) S-adenosyl-L-methionine + N2-methylguanine10 in tRNA S-adenosyl-L-homocysteine + N2-dimethylguanine10 in tRNA
Referencesedit
^Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H (August 2004). "N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota" (PDF). The Journal of Biological Chemistry. 279 (35): 37142–52. doi:10.1074/jbc.m403845200. PMID 15210688.
External linksedit
TRNA+(guanine10-N2)-dimethyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
trna, guanine10, dimethyltransferase, pab1283, dimethylguanosine, trna, methyltransferase, pabtrm, pabtrm, 2g10, enzyme, enzyme, with, systematic, name, adenosyl, methionine, trna, guanine10, dimethyltransferase, this, enzyme, catalyses, following, chemical, r. TRNA guanine10 N2 dimethyltransferase EC 2 1 1 213 PAB1283 N 2 N 2 dimethylguanosine tRNA methyltransferase Trm G10 PabTrm G10 PabTrm m2 2G10 enzyme is an enzyme with systematic name S adenosyl L methionine tRNA guanine10 N2 dimethyltransferase 1 This enzyme catalyses the following chemical reactionTRNA guanine10 N2 dimethyltransferaseIdentifiersEC no 2 1 1 213DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 2 S adenosyl L methionine guanine10 in tRNA displaystyle rightleftharpoons 2 S adenosyl L homocysteine N2 dimethylguanine10 in tRNA overall reaction 1a S adenosyl L methionine guanine10 in tRNA displaystyle rightleftharpoons S adenosyl L homocysteine N2 methylguanine10 in tRNA 1b S adenosyl L methionine N2 methylguanine10 in tRNA displaystyle rightleftharpoons S adenosyl L homocysteine N2 dimethylguanine10 in tRNAReferences edit Armengaud J Urbonavicius J Fernandez B Chaussinand G Bujnicki JM Grosjean H August 2004 N2 methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain containing S adenosylmethionine dependent methyltransferase conserved in Archaea and Eukaryota PDF The Journal of Biological Chemistry 279 35 37142 52 doi 10 1074 jbc m403845200 PMID 15210688 External links editTRNA guanine10 N2 dimethyltransferase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title TRNA guanine10 N2 dimethyltransferase amp oldid 1203784335, wikipedia, wiki, book, books, library,