Knockdown resistance, also called kdr, describes cases of resistance to diphenylethane (e.g. DDT) and pyrethroid[1] insecticides in insects and other arthropods that result from reduced sensitivity of the nervous system caused by point mutations in the insect population's genetic makeup. Such mutative resistance is characterized by the presence of kdr alleles in the insect's genome. Knockdown resistance, first identified and characterized in the house fly (Musca domestica) in the 1950s, remains a threat to the continued usefulness of pyrethroids in the control of many pest species. Research since 1990 has provided a wealth of new information on the molecular basis of knockdown resistance.[2]
Referencesedit
^Labbé, Pierrick; Alout, Haoues; Djogbénou, Luc; Pasteur, Nicole; Weill, Mylène (2011). "Evolution of Resistance to Insecticide in Disease Vectors". In Tibayrenc, Michel (ed.). Genetics and Evolution of Infectious Disease. Elsevier. pp. 363–409. ISBN978-0-12-384890-1.
^Zhu, F.; Wigginton, J.; Romero, A.; Moore, A.; Ferguson, K.; Palli, R.; Potter, M. F.; Haynes, K. F.; Palli, S. R. (April 2010). "Widespread distribution of knockdown resistance mutations in the bed bug, Cimex lectularius (Hemiptera: Cimicidae), populations in the United States". Archives of Insect Biochemistry and Physiology. 73 (4): 245–57. doi:10.1002/arch.20355. PMID 20301216.
April 18, 2024
knockdown, resistance, also, called, describes, cases, resistance, diphenylethane, pyrethroid, insecticides, insects, other, arthropods, that, result, from, reduced, sensitivity, nervous, system, caused, point, mutations, insect, population, genetic, makeup, s. Knockdown resistance also called kdr describes cases of resistance to diphenylethane e g DDT and pyrethroid 1 insecticides in insects and other arthropods that result from reduced sensitivity of the nervous system caused by point mutations in the insect population s genetic makeup Such mutative resistance is characterized by the presence of kdr alleles in the insect s genome Knockdown resistance first identified and characterized in the house fly Musca domestica in the 1950s remains a threat to the continued usefulness of pyrethroids in the control of many pest species Research since 1990 has provided a wealth of new information on the molecular basis of knockdown resistance 2 References edit Labbe Pierrick Alout Haoues Djogbenou Luc Pasteur Nicole Weill Mylene 2011 Evolution of Resistance to Insecticide in Disease Vectors In Tibayrenc Michel ed Genetics and Evolution of Infectious Disease Elsevier pp 363 409 ISBN 978 0 12 384890 1 Zhu F Wigginton J Romero A Moore A Ferguson K Palli R Potter M F Haynes K F Palli S R April 2010 Widespread distribution of knockdown resistance mutations in the bed bug Cimex lectularius Hemiptera Cimicidae populations in the United States Archives of Insect Biochemistry and Physiology 73 4 245 57 doi 10 1002 arch 20355 PMID 20301216 Retrieved from https en wikipedia org w index php title Knockdown resistance amp oldid 1117829477, wikipedia, wiki, book, books, library,
