The subependymal zone (SEZ) is a cell layer below the ependyma in the lateral ventricles of the brain. It is an adult version of the embryonic forebrain germinal zone. This region contains adult neural stem cells, also called neuroepithelial cells, which have the potential to generate new neurons and glial cells.[1] The generation of neurons and glial cells from neuroepithelial cells occurs via neurogenesis and gliogenesis, respectively. In adults, the subependymal zone is also called the subventricular zone, as the ependymal cell layer forms the boundary between the fluid-filled ventricular space and the walls of the lateral ventricles.[2]
Ilias Kazanis at the University of Cambridge compares the subependymal zone to a beating heart which "continuously sends new cells to different areas of the brain: neurons to the olfactory bulbs and glial cells to the cortex and the corpus callosum."[3]
^Kase, Yoshitaka; Shimazaki, Takuya; Okano, Hideyuki (2020-06-18). "Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age?". Inflammation and Regeneration. 40: 10. doi:10.1186/s41232-020-00122-x. ISSN 1880-9693. PMC7302355. PMID 32566044.
^Falcão, Ana Mendanha; Marques, Fernanda; Novais, Ashley; Sousa, Nuno; Palha, Joana A.; Sousa, João Carlos (2012-08-09). "The path from the choroid plexus to the subventricular zone: go with the flow!". Frontiers in Cellular Neuroscience. 6: 34. doi:10.3389/fncel.2012.00034. ISSN 1662-5102. PMC3414909. PMID 22907990.
^Kazanis, Ilias (2009). "The subependymal zone neurogenic niche: a beating heart in the centre of the brain". Brain. 132 (11): 2909–2921. doi:10.1093/brain/awp237. PMC2768664. PMID 19773354.
^Page 424 in: Neil Vasan; Le, Tao; Bhushan, Vikas (2010). First Aid for the USMLE Step 1, 2010 (First Aid USMLE). McGraw-Hill Medical. ISBN978-0-07-163340-6.
March 16, 2024
subependymal, zone, subependymal, zone, cell, layer, below, ependyma, lateral, ventricles, brain, adult, version, embryonic, forebrain, germinal, zone, this, region, contains, adult, neural, stem, cells, also, called, neuroepithelial, cells, which, have, poten. The subependymal zone SEZ is a cell layer below the ependyma in the lateral ventricles of the brain It is an adult version of the embryonic forebrain germinal zone This region contains adult neural stem cells also called neuroepithelial cells which have the potential to generate new neurons and glial cells 1 The generation of neurons and glial cells from neuroepithelial cells occurs via neurogenesis and gliogenesis respectively In adults the subependymal zone is also called the subventricular zone as the ependymal cell layer forms the boundary between the fluid filled ventricular space and the walls of the lateral ventricles 2 Ilias Kazanis at the University of Cambridge compares the subependymal zone to a beating heart which continuously sends new cells to different areas of the brain neurons to the olfactory bulbs and glial cells to the cortex and the corpus callosum 3 The subependymal zone is a region that may be affected by subependymal giant cell astrocytomas in people with tuberous sclerosis 4 References edit Kase Yoshitaka Shimazaki Takuya Okano Hideyuki 2020 06 18 Current understanding of adult neurogenesis in the mammalian brain how does adult neurogenesis decrease with age Inflammation and Regeneration 40 10 doi 10 1186 s41232 020 00122 x ISSN 1880 9693 PMC 7302355 PMID 32566044 Falcao Ana Mendanha Marques Fernanda Novais Ashley Sousa Nuno Palha Joana A Sousa Joao Carlos 2012 08 09 The path from the choroid plexus to the subventricular zone go with the flow Frontiers in Cellular Neuroscience 6 34 doi 10 3389 fncel 2012 00034 ISSN 1662 5102 PMC 3414909 PMID 22907990 Kazanis Ilias 2009 The subependymal zone neurogenic niche a beating heart in the centre of the brain Brain 132 11 2909 2921 doi 10 1093 brain awp237 PMC 2768664 PMID 19773354 Page 424 in Neil Vasan Le Tao Bhushan Vikas 2010 First Aid for the USMLE Step 1 2010 First Aid USMLE McGraw Hill Medical ISBN 978 0 07 163340 6 Retrieved from https en wikipedia org w index php title Subependymal zone amp oldid 1188167799, wikipedia, wiki, book, books, library,
