SSTs are sometimes called "marble-top tubes", "tiger-tops", or "gold-topped tubes", referring to the stoppers which are either gold, red with a gold ring on top, or marbled red and grey. The stopper of SPS (sodium polyanethol sulfonate) tubes have a paler yellow colour, sometimes causing confusion; these are known as "yellow tops" not "gold". Trademarked versions of the SST include Covidien "Corvac" tubes.
The tubes have micronized silica particles which help clot the blood before centrifugation, and a gel at the bottom which separates whole blood cells from serum.[1] Silica nanoparticles induce coagulation through contact activation of coagulation factor XII (Hageman factor).[2] The silica particles are desiccants, which adsorb and hold water vapor.[3] This is used in the tubes so the blood adheres to the surface of the tiny silica particles and begins to clot. After the blood sample is centrifuged, the clear serum should be removed for testing.[4][5]
These tubes should be used with care when measuring drug or hormone levels because the drug or hormone may diffuse from the serum into the gel, causing a reduction in measured level. The gel in SST II tubes (which appears slightly less opaque) is supposed[weasel words] to have less effect on drug levels in serum.[citation needed]
^(PDF). Purdue University. 2003. Archived from the original (PDF) on 2007-02-03.
^Thavasu PW, Longhurst S, Joel SP, Slevin ML, Balkwill FR (1992). "Measuring cytokine levels in blood. Importance of anticoagulants, processing, and storage conditions". J Immunol Methods. 153 (1–2): 115–24. doi:10.1016/0022-1759(92)90313-i. PMID 1381403.{{cite journal}}: CS1 maint: multiple names: authors list (link)
December 15, 2023
serum, separating, tube, also, known, serum, separator, tubes, ssts, test, tubes, used, clinical, chemistry, tests, requiring, blood, serum, large, vacutainerssts, sometimes, called, marble, tubes, tiger, tops, gold, topped, tubes, referring, stoppers, which, . Serum separating tubes also known as serum separator tubes or SSTs are test tubes used in clinical chemistry tests requiring blood serum A large SST II vacutainerSSTs are sometimes called marble top tubes tiger tops or gold topped tubes referring to the stoppers which are either gold red with a gold ring on top or marbled red and grey The stopper of SPS sodium polyanethol sulfonate tubes have a paler yellow colour sometimes causing confusion these are known as yellow tops not gold Trademarked versions of the SST include Covidien Corvac tubes The tubes have micronized silica particles which help clot the blood before centrifugation and a gel at the bottom which separates whole blood cells from serum 1 Silica nanoparticles induce coagulation through contact activation of coagulation factor XII Hageman factor 2 The silica particles are desiccants which adsorb and hold water vapor 3 This is used in the tubes so the blood adheres to the surface of the tiny silica particles and begins to clot After the blood sample is centrifuged the clear serum should be removed for testing 4 5 These tubes should be used with care when measuring drug or hormone levels because the drug or hormone may diffuse from the serum into the gel causing a reduction in measured level The gel in SST II tubes which appears slightly less opaque is supposed weasel words to have less effect on drug levels in serum citation needed See also editVacutainer VenipunctureReferences edit Greiner Bio One VACUETTE Z Serum Sep Clot Activator Tubes Non ridged pull cap Blood Hematology and Coagulation Testing Products Blood Specimen Collection www fishersci com Retrieved 2022 12 16 Ilinskaya Anna N Dobrovolskaia Marina A June 2013 Nanoparticles and the blood coagulation system Part II safety concerns Nanomedicine London England 8 6 969 981 doi 10 2217 nnm 13 49 ISSN 1743 5889 PMC 3939602 PMID 23730696 How Does Silica Gel Work retrieved 2022 12 16 Blood sampling in sheep PDF Purdue University 2003 Archived from the original PDF on 2007 02 03 Thavasu PW Longhurst S Joel SP Slevin ML Balkwill FR 1992 Measuring cytokine levels in blood Importance of anticoagulants processing and storage conditions J Immunol Methods 153 1 2 115 24 doi 10 1016 0022 1759 92 90313 i PMID 1381403 a href Template Cite journal html title Template Cite journal cite journal a CS1 maint multiple names authors list link Retrieved from https en wikipedia org w index php title Serum separating tube amp oldid 1177796362, wikipedia, wiki, book, books, library,
