fbpx
Wikipedia

Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) (EC 1.1.1.325) is an enzyme with systematic name L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
Identifiers
EC no.1.1.1.325
CAS no.9059-48-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
(1) L-threo-7,8-dihydrobiopterin + NADP+ sepiapterin + NADPH + H+
(2) L-threo-tetrahydrobiopterin + 2 NADP+ 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H+

This bacterial (Chlorobium tepidum) enzyme catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP.

References edit

  1. ^ Cho SH, Na JU, Youn H, Hwang CS, Lee CH, Kang SO (June 1999). "Sepiapterin reductase producing L-threo-dihydrobiopterin from Chlorobium tepidum". The Biochemical Journal. 340 ( Pt 2): 497–503. doi:10.1042/0264-6021:3400497. PMC 1220277. PMID 10333495.
  2. ^ Supangat S, Choi YK, Park YS, Son D, Han CD, Lee KH (February 2005). "Expression, purification, crystallization and preliminary X-ray analysis of sepiapterin reductase from Chlorobium tepidum". Acta Crystallographica Section F. 61 (Pt 2): 202–4. doi:10.1107/S174430910403444X. PMC 1952253. PMID 16510994.

External links edit

  • Sepiapterin+reductase+(L-threo-7,8-dihydrobiopterin+forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

sepiapterin, reductase, threo, dihydrobiopterin, forming, enzyme, with, systematic, name, threo, dihydrobiopterin, nadp, oxidoreductase, this, enzyme, catalyses, following, chemical, reactionidentifiersec, 325cas, 9059, 7databasesintenzintenz, viewbrendabrenda. Sepiapterin reductase L threo 7 8 dihydrobiopterin forming EC 1 1 1 325 is an enzyme with systematic name L threo 7 8 dihydrobiopterin NADP oxidoreductase 1 2 This enzyme catalyses the following chemical reactionSepiapterin reductase L threo 7 8 dihydrobiopterin forming IdentifiersEC no 1 1 1 325CAS no 9059 48 7DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 1 L threo 7 8 dihydrobiopterin NADP displaystyle rightleftharpoons sepiapterin NADPH H 2 L threo tetrahydrobiopterin 2 NADP displaystyle rightleftharpoons 6 pyruvoyl 5 6 7 8 tetrahydropterin 2 NADPH 2 H This bacterial Chlorobium tepidum enzyme catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP References edit Cho SH Na JU Youn H Hwang CS Lee CH Kang SO June 1999 Sepiapterin reductase producing L threo dihydrobiopterin from Chlorobium tepidum The Biochemical Journal 340 Pt 2 497 503 doi 10 1042 0264 6021 3400497 PMC 1220277 PMID 10333495 Supangat S Choi YK Park YS Son D Han CD Lee KH February 2005 Expression purification crystallization and preliminary X ray analysis of sepiapterin reductase from Chlorobium tepidum Acta Crystallographica Section F 61 Pt 2 202 4 doi 10 1107 S174430910403444X PMC 1952253 PMID 16510994 External links editSepiapterin reductase L threo 7 8 dihydrobiopterin forming at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title Sepiapterin reductase L threo 7 8 dihydrobiopterin forming amp oldid 1172360658, wikipedia, wiki, book, books, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.