This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. This enzyme participates in 3 metabolic pathways: 1- and 2-methylnaphthalene degradation, naphthalene and anthracene degradation, and fluorene degradation. It employs one cofactor, FAD.
Nomenclatureedit
The systematic name of this enzyme class is salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating).
Other names in common use include:
salicylate hydroxylase,
salicylate 1-hydroxylase,
salicylate monooxygenase, and
salicylate hydroxylase (decarboxylating)
Referencesedit
Suzuki K, Takemori S, Katagiri M (1969). "Mechanism of the salicylate hydroxylase reaction. IV. Fluorimetric analysis of the complex formation". Biochim. Biophys. Acta. 191: 77–85. doi:10.1016/0005-2744(69)90316-7.
Takemori S, Yasuda H, Mihara K, Suzuki K, Katagiri M (1969). "Mechanism of the salicylate hydroxylase reaction. II. The enzyme-substrate complex". Biochim. Biophys. Acta. 191 (1): 58–68. doi:10.1016/0005-2744(69)90314-3. PMID 4898626.
Takemori S, Yasuda H, Mihara K, Suzuki K, Katagiri M (1969). "Mechanism of the salicylate hydroxylase reaction. 3 Characterization and reactivity of chemically or photochemically reduced enzyme-flavin". Biochim. Biophys. Acta. 191 (1): 69–76. doi:10.1016/0005-2744(69)90315-5. PMID 4309912.
Yamamoto S, Katagiri M, Maeno H, Hayaishi O (1965). "Salicylate hydroxylase, a monooxygenase requiring flavin adenine dinucleotide". J. Biol. Chem. 240: 3408–3413. PMID 14321380.
salicylate, monooxygenase, enzymology, salicylate, monooxygenase, enzyme, that, catalyzes, chemical, reactionsalicylate, monooxygenaseidentifiersec, 1cas, 9059, 3databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic,. In enzymology a salicylate 1 monooxygenase EC 1 14 13 1 is an enzyme that catalyzes the chemical reactionsalicylate 1 monooxygenaseIdentifiersEC no 1 14 13 1CAS no 9059 28 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins salicylate NADH 2 H O2 displaystyle rightleftharpoons catechol NAD H2O CO2 The 4 substrates of this enzyme are salicylate NADH H and O2 whereas its 4 products are catechol NAD H2O and CO2 This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor and incorporation of one atom o oxygen into the other donor This enzyme participates in 3 metabolic pathways 1 and 2 methylnaphthalene degradation naphthalene and anthracene degradation and fluorene degradation It employs one cofactor FAD Nomenclature editThe systematic name of this enzyme class is salicylate NADH oxygen oxidoreductase 1 hydroxylating decarboxylating Other names in common use include salicylate hydroxylase salicylate 1 hydroxylase salicylate monooxygenase and salicylate hydroxylase decarboxylating References editSuzuki K Takemori S Katagiri M 1969 Mechanism of the salicylate hydroxylase reaction IV Fluorimetric analysis of the complex formation Biochim Biophys Acta 191 77 85 doi 10 1016 0005 2744 69 90316 7 Takemori S Yasuda H Mihara K Suzuki K Katagiri M 1969 Mechanism of the salicylate hydroxylase reaction II The enzyme substrate complex Biochim Biophys Acta 191 1 58 68 doi 10 1016 0005 2744 69 90314 3 PMID 4898626 Takemori S Yasuda H Mihara K Suzuki K Katagiri M 1969 Mechanism of the salicylate hydroxylase reaction 3 Characterization and reactivity of chemically or photochemically reduced enzyme flavin Biochim Biophys Acta 191 1 69 76 doi 10 1016 0005 2744 69 90315 5 PMID 4309912 Yamamoto S Katagiri M Maeno H Hayaishi O 1965 Salicylate hydroxylase a monooxygenase requiring flavin adenine dinucleotide J Biol Chem 240 3408 3413 PMID 14321380 Portal nbsp Biology This EC 1 14 13 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Salicylate 1 monooxygenase amp oldid 1198181732, wikipedia, wiki, book, books, library,
