Additionally, in many strains of the yeast, it is found along with another virus called the M virus (or "M dsRNA", "Saccharomyces cerevisiae killer virus"), known to encode the killer toxin in many S. cerevisiae strains which confers the ability to kill neighboring sensitive cells that do not harbor the virus. It is indeed for this reason the virus is referred to as a helper virus, due to the M genome's dependence on it for its own survival and replication. (More recently, the M dsRNA is described as a satellite RNA.) A Yeast lineage with a M/killer virus is known as a "killer strain".[5]
There are numerous apparently unrelated M dsRNAs that use L-A, their only similarity being their genome organization. The family of Totiviridae in general helps M-type dsRNAs in a wide variety of yeasts.[5]
Referencesedit
^Francki, R.I.B.; Fauquet, C.M.; Knudson, D.L.; Brown, F., eds. (1991). Classification and nomenclature of viruses. Fifth report of the International Committee on Taxonomy of Viruses(PDF). Archives of Virology Supplementum 2.
^"MINUTES OF THE SIXTH MEETING OF THE ICTV, SENDAI, 5th SEPTEMBER 1984" (PDF). International Committee on Taxonomy of Viruses (ICTV). 5 September 1984. Retrieved 10 February 2020.
^Rodríguez-Cousiño, Nieves; Esteban, Rosa (2017-02-15). "Relationships and Evolution of Double-Stranded RNA Totiviruses of Yeasts Inferred from Analysis of L-A-2 and L-BC Variants in Wine Yeast Strain Populations". Applied and Environmental Microbiology. 83 (4). Bibcode:2017ApEnM..83E2991R. doi:10.1128/AEM.02991-16. PMC5288835. PMID 27940540.
^ abRamírez, M; Velázquez, R; López-Piñeiro, A; Naranjo, B; Roig, F; Llorens, C (19 September 2017). "New Insights into the Genome Organization of Yeast Killer Viruses Based on "Atypical" Killer Strains Characterized by High-Throughput Sequencing". Toxins. 9 (9): 292. doi:10.3390/toxins9090292. PMC5618225. PMID 28925975.
November 23, 2023
saccharomyces, cerevisiae, virus, also, called, helper, virus, member, totiviridae, family, viruses, found, primarily, saccharomyces, cerevisiae, discovery, 1970s, main, starting, point, research, yeast, virology, double, stranded, virus, with, extracellular, . Saccharomyces cerevisiae virus L A also called L A helper virus is a member of the Totiviridae family of viruses found primarily in Saccharomyces cerevisiae 3 Its discovery in the 1970s was the main starting point of research on yeast virology 4 It is a 4 6 kb double stranded RNA virus with no extracellular phase and so is inherited through vertical cytoplasmic transmission 4 Saccharomyces cerevisiae virus L AScV L A capsid protein structure and homodimer of the gag capsid proteinVirus classification unranked VirusRealm RiboviriaKingdom OrthornaviraePhylum DuplornaviricotaClass ChrymotiviricetesOrder GhabriviralesFamily TotiviridaeGenus TotivirusSpecies Saccharomyces cerevisiae virus L ASynonymsSaccharomyces cerevisiae virus LA 1 Saccharomyces cerevisiae virus ScV1 2 Replication cycle of L A helper and M28 K28 killer viruses in S cerevisiae Additionally in many strains of the yeast it is found along with another virus called the M virus or M dsRNA Saccharomyces cerevisiae killer virus known to encode the killer toxin in many S cerevisiae strains which confers the ability to kill neighboring sensitive cells that do not harbor the virus It is indeed for this reason the virus is referred to as a helper virus due to the M genome s dependence on it for its own survival and replication More recently the M dsRNA is described as a satellite RNA A Yeast lineage with a M killer virus is known as a killer strain 5 There are numerous apparently unrelated M dsRNAs that use L A their only similarity being their genome organization The family of Totiviridae in general helps M type dsRNAs in a wide variety of yeasts 5 References edit Francki R I B Fauquet C M Knudson D L Brown F eds 1991 Classification and nomenclature of viruses Fifth report of the International Committee on Taxonomy of Viruses PDF Archives of Virology Supplementum 2 MINUTES OF THE SIXTH MEETING OF THE ICTV SENDAI 5th SEPTEMBER 1984 PDF International Committee on Taxonomy of Viruses ICTV 5 September 1984 Retrieved 10 February 2020 Rodriguez Cousino Nieves Esteban Rosa 2017 02 15 Relationships and Evolution of Double Stranded RNA Totiviruses of Yeasts Inferred from Analysis of L A 2 and L BC Variants in Wine Yeast Strain Populations Applied and Environmental Microbiology 83 4 Bibcode 2017ApEnM 83E2991R doi 10 1128 AEM 02991 16 PMC 5288835 PMID 27940540 a b Schmitt Manfred J Breinig Frank March 10 2006 Yeast viral killer toxins lethality and self protection Nature Reviews Microbiology 4 3 212 221 doi 10 1038 nrmicro1347 PMID 16489348 S2CID 24668951 a b Ramirez M Velazquez R Lopez Pineiro A Naranjo B Roig F Llorens C 19 September 2017 New Insights into the Genome Organization of Yeast Killer Viruses Based on Atypical Killer Strains Characterized by High Throughput Sequencing Toxins 9 9 292 doi 10 3390 toxins9090292 PMC 5618225 PMID 28925975 Retrieved from https en wikipedia org w index php title Saccharomyces cerevisiae virus L A amp oldid 1177076103, wikipedia, wiki, book, books, library,