Rickettsia felis is a species of bacterium, the pathogen that causes cat-flea typhus in humans, also known as flea-borne spotted fever.[3]Rickettsia felis also is regarded as the causative organism of many cases of illnesses generally classed as fevers of unknown origin in humans in Africa.
Until recently, fleas have been the recognised vectors of Rickettsia felis and it is present in cat flea populations of North and South America, Southern Europe, Africa, Thailand and Australia. Human infection usually results from flea feces coming into contact with scratched or broken skin.[4]
More recently, some authorities have published increasing concerns about the role of more and more species of arthropod vectors of this organism; Rickettsia felis has by now been detected in many arthropods in the wild, including various species of mites, ticks, blood-sucking bugs in the genus Cimex, sucking lice, flea species of various types, both free-living and "sticktight fleas", and various other biting insects.[5] In particular there is concern about the prevalence of Rickettsia felis in regions such as parts of sub-Saharan Africa, in mosquito genera such as Anopheles, Aedes, Mansonia, and Culex; all of these genera include species that are challenging to control and have long been recognised as effective vectors of various important human and animal diseases.[5]
The mosquito species Anopheles gambiae, which is notorious mainly as a malaria vector, has been demonstrated to be a competent vector for Rickettsia felis. More unexpectedly, cells of some important disease vector species of mosquitoes in the genus Aedes, which is most commonly seen as a vector for arboviruses, support growth of Rickettsia felis.[6] In addition, in tropical regions where Aedes albopictus and Aedes aegypti are established disease vectors and ectoparasites of humans, patients have tested positive for Rickettsia felis. To some authorities this suggests that Aedes species might be able to infect their hosts with Rickettsia felis, and that patients in, or returning from, the tropics with fevers of unknown origin, should be tested for Rickettsia felis infection. They see as very real, the possibility that Rickettsia felis might be the next mosquito-borne pathogen to emerge as a multi-continental disease outbreak.[6]
Australiaedit
Human cases of Rickettsia felis were diagnosed in Australia in 2009, these were the first reported human infections in Australia.[7] The infected individuals were family members who had been exposed to flea bites from infested kittens. In this cluster an otherwise healthy nine-year-old girl was admitted to hospital with fever and a rash. This later worsened three days later when her lungs filled with fluid and she was admitted to intensive care.[8]
Referencesedit
^Bouyer DH, Stenos J, Crocquet-Valdes P, et al. (March 2001). "Rickettsia felis: molecular characterization of a new member of the spotted fever group". Int. J. Syst. Evol. Microbiol. 51 (Pt 2): 339–47. doi:10.1099/00207713-51-2-339. PMID 11321078.
^La Scola B, Meconi S, Fenollar F, Rolain JM, Roux V, Raoult D (November 2002). "Emended description of Rickettsia felis (Bouyer et al. 2001), a temperature-dependent cultured bacterium". Int. J. Syst. Evol. Microbiol. 52 (Pt 6): 2035–41. doi:10.1099/00207713-52-6-2035. PMID 12508865.
^Raoult, Didier; Parola, Philippe (2007). Rickettsial diseases. CRC Press. pp. 87–. ISBN978-0-8493-7611-5. Retrieved 23 May 2010.
^Azad AF, Beard CB (1998). "Rickettsial pathogens and their arthropod vectors". Emerging Infect. Dis. 4 (2): 179–86. doi:10.3201/eid0402.980205. PMC2640117. PMID 9621188.
^ abBrown, Lisa D. Macaluso, Kevin R. Rickettsia felis, an Emerging Flea-Borne Rickettsiosis. Curr Trop Med Rep (2016) 3: 27. doi:10.1007/s40475-016-0070-6
^ abParola, Philippe. Musso, Didier. Raoult, Didier. Rickettsia felis: the next mosquito-borne outbreak? The Lancet Infectious Diseases, Volume 16, Issue 10, 1112 - 1113
^Williams M, Izzard L, Graves SR, Stenos J, Kelly JJ (January 2011). "First probable Australian cases of human infection with Rickettsia felis (cat-flea typhus)". Med. J. Aust. 194 (1): 41–3. doi:10.5694/j.1326-5377.2011.tb04145.x. PMID 21449868. S2CID 22677434.
^Medew J (6 January 2011). "Deadly cat-flea disease hits Australia". The Age.
External linksedit
"Rickettsia felis". NCBI Taxonomy Browser. 42862.
January 01, 1970
rickettsia, felis, species, bacterium, pathogen, that, causes, flea, typhus, humans, also, known, flea, borne, spotted, fever, also, regarded, causative, organism, many, cases, illnesses, generally, classed, fevers, unknown, origin, humans, africa, scientific,. Rickettsia felis is a species of bacterium the pathogen that causes cat flea typhus in humans also known as flea borne spotted fever 3 Rickettsia felis also is regarded as the causative organism of many cases of illnesses generally classed as fevers of unknown origin in humans in Africa Rickettsia felis Scientific classification Domain Bacteria Phylum Pseudomonadota Class Alphaproteobacteria Order Rickettsiales Family Rickettsiaceae Genus Rickettsia Species group Spotted fever group Species R felis Binomial name Rickettsia felisBouyer et al 2001 1 emend La Scola et al 2002 2 Contents 1 Transmission and concerns 2 Australia 3 References 4 External linksTransmission and concerns editUntil recently fleas have been the recognised vectors of Rickettsia felis and it is present in cat flea populations of North and South America Southern Europe Africa Thailand and Australia Human infection usually results from flea feces coming into contact with scratched or broken skin 4 More recently some authorities have published increasing concerns about the role of more and more species of arthropod vectors of this organism Rickettsia felis has by now been detected in many arthropods in the wild including various species of mites ticks blood sucking bugs in the genus Cimex sucking lice flea species of various types both free living and sticktight fleas and various other biting insects 5 In particular there is concern about the prevalence of Rickettsia felis in regions such as parts of sub Saharan Africa in mosquito genera such as Anopheles Aedes Mansonia and Culex all of these genera include species that are challenging to control and have long been recognised as effective vectors of various important human and animal diseases 5 The mosquito species Anopheles gambiae which is notorious mainly as a malaria vector has been demonstrated to be a competent vector for Rickettsia felis More unexpectedly cells of some important disease vector species of mosquitoes in the genus Aedes which is most commonly seen as a vector for arboviruses support growth of Rickettsia felis 6 In addition in tropical regions where Aedes albopictus and Aedes aegypti are established disease vectors and ectoparasites of humans patients have tested positive for Rickettsia felis To some authorities this suggests that Aedes species might be able to infect their hosts with Rickettsia felis and that patients in or returning from the tropics with fevers of unknown origin should be tested for Rickettsia felis infection They see as very real the possibility that Rickettsia felis might be the next mosquito borne pathogen to emerge as a multi continental disease outbreak 6 Australia editHuman cases of Rickettsia felis were diagnosed in Australia in 2009 these were the first reported human infections in Australia 7 The infected individuals were family members who had been exposed to flea bites from infested kittens In this cluster an otherwise healthy nine year old girl was admitted to hospital with fever and a rash This later worsened three days later when her lungs filled with fluid and she was admitted to intensive care 8 References edit Bouyer DH Stenos J Crocquet Valdes P et al March 2001 Rickettsia felis molecular characterization of a new member of the spotted fever group Int J Syst Evol Microbiol 51 Pt 2 339 47 doi 10 1099 00207713 51 2 339 PMID 11321078 La Scola B Meconi S Fenollar F Rolain JM Roux V Raoult D November 2002 Emended description of Rickettsia felis Bouyer et al 2001 a temperature dependent cultured bacterium Int J Syst Evol Microbiol 52 Pt 6 2035 41 doi 10 1099 00207713 52 6 2035 PMID 12508865 Raoult Didier Parola Philippe 2007 Rickettsial diseases CRC Press pp 87 ISBN 978 0 8493 7611 5 Retrieved 23 May 2010 Azad AF Beard CB 1998 Rickettsial pathogens and their arthropod vectors Emerging Infect Dis 4 2 179 86 doi 10 3201 eid0402 980205 PMC 2640117 PMID 9621188 a b Brown Lisa D Macaluso Kevin R Rickettsia felis an Emerging Flea Borne Rickettsiosis Curr Trop Med Rep 2016 3 27 doi 10 1007 s40475 016 0070 6 a b Parola Philippe Musso Didier Raoult Didier Rickettsia felis the next mosquito borne outbreak The Lancet Infectious Diseases Volume 16 Issue 10 1112 1113 Williams M Izzard L Graves SR Stenos J Kelly JJ January 2011 First probable Australian cases of human infection with Rickettsia felis cat flea typhus Med J Aust 194 1 41 3 doi 10 5694 j 1326 5377 2011 tb04145 x PMID 21449868 S2CID 22677434 Medew J 6 January 2011 Deadly cat flea disease hits Australia The Age External links edit Rickettsia felis NCBI Taxonomy Browser 42862 Retrieved from https en wikipedia org w index php title Rickettsia felis amp oldid 1109610088, wikipedia, wiki, book, books, library,
