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Richard Grant Hiskey

Richard G. Hiskey (May 21, 1929 – July 28, 2016[1]) was an American chemist and Alumni Distinguished Professor of Chemistry at University of North Carolina at Chapel Hill. Hiskey joined the department of chemistry of the University of North Carolina at Chapel Hill in 1958. He served in various capacities within the university, including director of graduate studies (1965-1970) and chairman of the department (1970-1975), (elected) chairman of the division of natural sciences from 1975 to 1981, and faculty representative to the Atlantic Coast Conference and National Association of Intercollegiate Athletics (1985-1995).

Richard Grant "Dick" Hiskey
Born(1929-05-21)May 21, 1929
DiedJuly 28, 2016(2016-07-28) (aged 87)
Alma materKansas State College
Kansas State University
Wayne State University
OccupationProfessor
Known forDisulfides
Spouse
Joan T. Crooke
(m. 1953)
[citation needed]
Children5
Scientific career
FieldsChemistry
Organic chemistry
InstitutionsUniversity of North Carolina at Chapel Hill

Academic career edit

He received the Standard Oil Foundation for Excellence in Undergraduate Teaching Award in 1970; the Tanner Award for Excellence in Undergraduate Teaching in 1986; and he was elected by students to membership in the Society of the Golden Fleece in 1989. He collaborated with 55 M.S. and Ph.D. colleagues resulting in over 160 referred publications in journals and edited volumes. Following Hiskey's retirement in 1996, the department created the Richard G. Hiskey Graduate Student Fellowship dedicated to the recruitment and retention of outstanding graduate students.

Hiskey received Outstanding Alumnus Awards from Kansas State University in 1973, Wayne State University in 1978, Emporia State University in 1979, and the UNC-CH General Alumni Association Faculty Service Award in 1992. He also was a John Simon Guggenheim Foundation Fellow and a Kenan Research Leave Fellow in 1970–71 at the Max Planck Institute for Cell Chemistry.

Hiskey's initial research concerned the development of methods for the production of "mixed sulfides" and the features which stabilized or destabilized these molecules. Mixed disulfides occur in the folding and stabilization of proteins via cystine-cystine interactions. Pursuit of the synthesis of insulin led to the development of methods for the production of mixed disulfides containing two or more cystine residues differently S-protected.

The second major phase of Hiskey's research program concerned the role of protein-bound X-Carboxyglutamic (GLA) residues in blood clot formation. He developed a method for chemical modification of the GLA residues in 1982 and studied it using various metal ims and prothrombin fragments binding to phospholipid surfaces. These studies were recognized in Hiskey's National Heart, Lung and Blood Institute's Merit Award for the period 1986 to 1996.

The study was extended to include various models containing tris-phosphates and peptides containing several GLA residues. Hiskey's interest in peptide synthesis resulted in membership on the Organization Committee of the American Peptide Symposium from 1978 to 1983, as well as from 1988 to 1990, and co-chairman of the 1982 Gordon Research Conference on the Chemistry and Biology of Peptides. Hiskey also received and accepted an invitation to visit Japan as a Japan Society for the Promotion of Science Fellow as a result of his work on peptide synthesis. Finally, the American Peptide Society presented Hiskey with the Society's Annual Award in June 1996. In that same year, Hiskey retired from the University of North Carolina as Alumni Distinguished Professor Emeritus.

Honors edit

References edit

  1. ^ Hiskey, Richard, Published in The News & Observer on July 31, 2016
  2. ^ RICHARD G. HISKEY, Fellow profile, John Simmon Guggenheim Foundation, Accessed September 12, 2016
  3. ^ RICHARD G HISKEY, AAAS Fellow, American Association for the Advancement of Science. Accessed September 12, 2016
  4. ^ The Vincent du Vigneaud Award, American Peptide Society. Accessed September 12, 2016

Images edit

richard, grant, hiskey, richard, hiskey, 1929, july, 2016, american, chemist, alumni, distinguished, professor, chemistry, university, north, carolina, chapel, hill, hiskey, joined, department, chemistry, university, north, carolina, chapel, hill, 1958, served. Richard G Hiskey May 21 1929 July 28 2016 1 was an American chemist and Alumni Distinguished Professor of Chemistry at University of North Carolina at Chapel Hill Hiskey joined the department of chemistry of the University of North Carolina at Chapel Hill in 1958 He served in various capacities within the university including director of graduate studies 1965 1970 and chairman of the department 1970 1975 elected chairman of the division of natural sciences from 1975 to 1981 and faculty representative to the Atlantic Coast Conference and National Association of Intercollegiate Athletics 1985 1995 Richard Grant Dick HiskeyBorn 1929 05 21 May 21 1929Emporia Kansas U S DiedJuly 28 2016 2016 07 28 aged 87 Alma materKansas State CollegeKansas State UniversityWayne State UniversityOccupationProfessorKnown forDisulfidesSpouseJoan T Crooke m 1953 wbr citation needed Children5Scientific careerFieldsChemistryOrganic chemistryInstitutionsUniversity of North Carolina at Chapel Hill Contents 1 Academic career 2 Honors 3 References 3 1 ImagesAcademic career editHe received the Standard Oil Foundation for Excellence in Undergraduate Teaching Award in 1970 the Tanner Award for Excellence in Undergraduate Teaching in 1986 and he was elected by students to membership in the Society of the Golden Fleece in 1989 He collaborated with 55 M S and Ph D colleagues resulting in over 160 referred publications in journals and edited volumes Following Hiskey s retirement in 1996 the department created the Richard G Hiskey Graduate Student Fellowship dedicated to the recruitment and retention of outstanding graduate students Hiskey received Outstanding Alumnus Awards from Kansas State University in 1973 Wayne State University in 1978 Emporia State University in 1979 and the UNC CH General Alumni Association Faculty Service Award in 1992 He also was a John Simon Guggenheim Foundation Fellow and a Kenan Research Leave Fellow in 1970 71 at the Max Planck Institute for Cell Chemistry Hiskey s initial research concerned the development of methods for the production of mixed sulfides and the features which stabilized or destabilized these molecules Mixed disulfides occur in the folding and stabilization of proteins via cystine cystine interactions Pursuit of the synthesis of insulin led to the development of methods for the production of mixed disulfides containing two or more cystine residues differently S protected The second major phase of Hiskey s research program concerned the role of protein bound X Carboxyglutamic GLA residues in blood clot formation He developed a method for chemical modification of the GLA residues in 1982 and studied it using various metal ims and prothrombin fragments binding to phospholipid surfaces These studies were recognized in Hiskey s National Heart Lung and Blood Institute s Merit Award for the period 1986 to 1996 The study was extended to include various models containing tris phosphates and peptides containing several GLA residues Hiskey s interest in peptide synthesis resulted in membership on the Organization Committee of the American Peptide Symposium from 1978 to 1983 as well as from 1988 to 1990 and co chairman of the 1982 Gordon Research Conference on the Chemistry and Biology of Peptides Hiskey also received and accepted an invitation to visit Japan as a Japan Society for the Promotion of Science Fellow as a result of his work on peptide synthesis Finally the American Peptide Society presented Hiskey with the Society s Annual Award in June 1996 In that same year Hiskey retired from the University of North Carolina as Alumni Distinguished Professor Emeritus Honors editJohn Simmon Guggenheim Foundation Fellow 1970 71 2 Standard Oil Foundation Award for Excellence in Undergraduate Teaching 1970 Kenan Research Leave University of North Carolina 1970 71 Outstanding Alumnus Award department of chemistry Kansas State University 1973 Distinguished Alumnus Award Wayne State University 1978 Distinguished Alumnus Award Emporia State University 1979 Co chairman 1982 Gordon Res Conf on Chem Biol of Peptides Japan Society for Promotion of Science Fellow 1983 Elected Fellow American Association for the Advancement of Science 1983 3 Tanner Award for Excellence in Undergraduate Teaching 1986 Merit Award National Heart Lung and Blood Institute National Institute of Health 1986 National Heart Lung and Blood Institute Merit Award recipient 1986 Society of the Golden Fleece University of North Carolina 1989 Faculty Service Award Alumni Association 1992 Vincent du Vigneaud Award of the American Peptide Society 1996 4 References edit Hiskey Richard Published in The News amp Observer on July 31 2016 RICHARD G HISKEY Fellow profile John Simmon Guggenheim Foundation Accessed September 12 2016 RICHARD G HISKEY AAAS Fellow American Association for the Advancement of Science Accessed September 12 2016 The Vincent du Vigneaud Award American Peptide Society Accessed September 12 2016 Images edit Retrieved from https en 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