The nucleus raphe obscurus, despite the implications of its name, has some very specific functions and connections of afferent and efferent nature. The nucleus raphes obscurus projects to the cerebellar lobes VI and VII and to crus II along with the nucleus raphe pontis.[1]
Nucleus raphe obscurus
Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but 'raphe' labeled at left.)
The nucleus raphes obscurus has also been implicated in the modulation of the hypoglossal nerve. It has been observed that the ablation of this nucleus causes a change in the firing pattern of this cranial nerve.[2]
In addition, the nucleus raphe obscurus mediates expiration via the effect of serotonin and depresses periodic synaptic potentials.[3] It has also been shown that this nucleus stimulates gastrointestinal motor function; microinjections of 5-HT into the nucleus raphe obscurus increase gastric movement.[4]
^Krowicki, ZK; Hornby, PJ (1993). "Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway". Journal of Pharmacology and Experimental Therapeutics. 265 (1): 468–476. PMID 8097247.
January 01, 1970
nucleus, raphe, obscurus, nucleus, raphe, obscurus, despite, implications, name, some, very, specific, functions, connections, afferent, efferent, nature, nucleus, raphes, obscurus, projects, cerebellar, lobes, crus, along, with, nucleus, raphe, pontis, sectio. The nucleus raphe obscurus despite the implications of its name has some very specific functions and connections of afferent and efferent nature The nucleus raphes obscurus projects to the cerebellar lobes VI and VII and to crus II along with the nucleus raphe pontis 1 Nucleus raphe obscurusSection of the medulla oblongata at about the middle of the olive Raphe nuclei not labeled but raphe labeled at left DetailsIdentifiersLatinnucleus raphes obscurusMeSHD065849NeuroNames740NeuroLex IDbirnlex 1369TA98A14 1 04 319TA26037FMA72585Anatomical terms of neuroanatomy edit on Wikidata The nucleus raphes obscurus has also been implicated in the modulation of the hypoglossal nerve It has been observed that the ablation of this nucleus causes a change in the firing pattern of this cranial nerve 2 In addition the nucleus raphe obscurus mediates expiration via the effect of serotonin and depresses periodic synaptic potentials 3 It has also been shown that this nucleus stimulates gastrointestinal motor function microinjections of 5 HT into the nucleus raphe obscurus increase gastric movement 4 See also editRaphe nucleiReferences edit Brodal A 1981 Neurological Anatomy in relation to Clinical Medication 3rd ed Oxford Press ISBN 978 0195026948 Peever JH Necakov A Duffin J 2001 Nucleus raphe obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices Journal of Applied Physiology 90 1 269 279 doi 10 1152 jappl 2001 90 1 269 PMID 11133919 Lalley PM Benacka R Bischoff AM Richter DW 1997 Nucleus raphe obscurus evokes 5 HT 1A receptor mediated modulation of respiratory neurons Brain Research 747 1 156 159 doi 10 1016 S0006 8993 96 01233 4 PMID 9042541 Krowicki ZK Hornby PJ 1993 Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway Journal of Pharmacology and Experimental Therapeutics 265 1 468 476 PMID 8097247 Retrieved from https en wikipedia org w index php title Nucleus raphe obscurus amp oldid 1023385788, wikipedia, wiki, book, books, library,
