Example of a workup algorithm of possible bacterial infection in cases with no specifically requested targets (non-bacteria, mycobacteria etc.), with most common situations and agents seen in a New England community hospital setting. As seen in bottom right quadrant, Pseudomonas infection may be identified by MALDI-TOF if such machine is available. Otherwise, it usually shows relatively characteristic growth on agar plates.
P. aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients, such as those with cancer, diabetes, cystic fibrosis,[1] severe burns, AIDS,[2] or people who are very young or elderly. Infection can affect many parts of the body, but infections typically target the respiratory tract, the renal system, the gastrointestinal system or it can cause blood infection. The symptoms include bacterial pneumonia, severe coughing, congestion, UTI, pain in the ears and eyes, joint pain, neck or back pain, headache, diarrhea, a rash which can include pimples filled with pus, and/or swelling in the eyes. Complications include pneumonia, gangrene, necrotizing fasciitis, compartment syndrome, necrosis, loss of an extremity, and Septicemia, which may lead to septic shock and death. In a surveillance study between 1986 and 1989, P. aeruginosa was the third leading cause of all nosocomial infections, and specifically the number one leading cause of hospital-acquired pneumonia and third leading cause of hospital-acquired UTI.[3] Treatment of such infections can be difficult due to multiple antibiotic resistance,[4] and in the United States, there was an increase in MDRPA (Multidrug-resistant Pseudomonas aeruginosa) resistant to ceftazidime, ciprofloxacin, and aminoglycosides, from 0.9% in 1994 to 5.6% in 2002.[5]
Due to their hemolytic activity, even non-pathogenic species of Pseudomonas can occasionally become a problem in clinical settings, where they have been known to infect blood transfusions.[11]
See alsoedit
Wikimedia Commons has media related to Pseudomonas infections.
Referencesedit
^Elkin S, Geddes D (2003). "Pseudomonal infection in cystic fibrosis: the battle continues". Expert Review of Anti-infective Therapy. 1 (4): 609–18. doi:10.1586/14787210.1.4.609. PMID 15482158. S2CID 33383226.
^Shanson DC (1990). "Septicaemia in patients with AIDS". Trans. R. Soc. Trop. Med. Hyg. 84 Suppl 1: 14–6. doi:10.1016/0035-9203(90)90449-o. PMID 2201108.
^Schaberd; Culver; Gaynes (1991). "Major trends in the microbial etiology of nosocomial infection" (PDF). The American Journal of Medicine. 91 (3): S72–S75. doi:10.1016/0002-9343(91)90346-Y. hdl:2027.42/29131. PMID 1928195.
^McGowan JE (2006). "Resistance in nonfermenting gram-negative bacteria: multidrug resistance to the maximum". Am. J. Med. 119 (6 Suppl 1): S29–36, discussion S62–70. doi:10.1016/j.amjmed.2006.03.014. PMID 16735148.
^Obritsch; Fish; MacLauren; Jung (2005). "Nosocomial Infections Due to Multidrug-Resistant Pseudomonas aeruginosa: Epidemiology and Treatment Options". Pharmacotherapy. 25 (10): 1353–1364. doi:10.1592/phco.2005.25.10.1353. PMID 16185180. S2CID 36236448.
^Levitski-Heikkila TV, Ullian ME (2005). "Peritonitis with multiple rare environmental bacteria in a patient receiving long-term peritoneal dialysis". Am. J. Kidney Dis. 46 (6): e119–24. doi:10.1053/j.ajkd.2005.08.021. PMID 16310563.
^Yu EN, Foster CS (2002). "Chronic postoperative endophthalmitis due to Pseudomonas oryzihabitans". Am. J. Ophthalmol. 134 (4): 613–4. doi:10.1016/S0002-9394(02)01586-6. PMID 12383826.
^Kodama K, Kimura Nm Komagata K (1985). "Two new species of Pseudomonas: P. oryzihabitans isolated from rice paddy and clinical specimens and P. luteola isolated from clinical specimens". Int J Syst Bacteriol. 35 (Pt 2): 467–74. doi:10.1099/00207713-35-4-467.
^Nishimori E, Kita-Tsukamoto K, Wakabayashi H (2000). "Pseudomonas plecoglossicida sp. nov., the causative agent of bacterial haemorrhagic ascites of ayu, Plecoglossus altivelis". Int. J. Syst. Evol. Microbiol. 50 (1): 83–9. doi:10.1099/00207713-50-1-83. PMID 10826790.
^López-Romalde S, Magariños B, Ravelo C, Toranzo AE, Romalde JL (2003). "Existence of two O-serotypes in the fish pathogen Pseudomonas anguilliseptica". Vet. Microbiol. 94 (4): 325–33. doi:10.1016/S0378-1135(03)00124-X. PMID 12829386.
^Khabbaz RF, Arnow PM, Highsmith AK, et al. (1984). "Pseudomonas fluorescens bacteremia from blood transfusion". Am. J. Med. 76 (1): 62–8. doi:10.1016/0002-9343(84)90751-4. PMID 6419604.
External linksedit
April 10, 2024
pseudomonas, infection, refers, disease, caused, species, genus, pseudomonas, other, namespseudomoniasis, pseudomonosisspecialtyinfectious, diseases, pulmonology, pediatrics, prognosis18, 61cfrexample, workup, algorithm, possible, bacterial, infection, cases, . Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas Pseudomonas infectionOther namespseudomoniasis pseudomonosisSpecialtyInfectious diseases pulmonology pediatrics Prognosis18 61CFRExample of a workup algorithm of possible bacterial infection in cases with no specifically requested targets non bacteria mycobacteria etc with most common situations and agents seen in a New England community hospital setting As seen in bottom right quadrant Pseudomonas infection may be identified by MALDI TOF if such machine is available Otherwise it usually shows relatively characteristic growth on agar plates P aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients such as those with cancer diabetes cystic fibrosis 1 severe burns AIDS 2 or people who are very young or elderly Infection can affect many parts of the body but infections typically target the respiratory tract the renal system the gastrointestinal system or it can cause blood infection The symptoms include bacterial pneumonia severe coughing congestion UTI pain in the ears and eyes joint pain neck or back pain headache diarrhea a rash which can include pimples filled with pus and or swelling in the eyes Complications include pneumonia gangrene necrotizing fasciitis compartment syndrome necrosis loss of an extremity and Septicemia which may lead to septic shock and death In a surveillance study between 1986 and 1989 P aeruginosa was the third leading cause of all nosocomial infections and specifically the number one leading cause of hospital acquired pneumonia and third leading cause of hospital acquired UTI 3 Treatment of such infections can be difficult due to multiple antibiotic resistance 4 and in the United States there was an increase in MDRPA Multidrug resistant Pseudomonas aeruginosa resistant to ceftazidime ciprofloxacin and aminoglycosides from 0 9 in 1994 to 5 6 in 2002 5 P oryzihabitans can also be a human pathogen although infections are rare It can cause peritonitis 6 endophthalmitis 7 sepsis and bacteremia Similar symptoms although also very rare can be seen by infections of P luteola 8 P plecoglossicida is a fish pathogenic species causing hemorrhagic ascites in the ayu Plecoglossus altivelis 9 P anguilliseptica is also a fish pathogen 10 Due to their hemolytic activity even non pathogenic species of Pseudomonas can occasionally become a problem in clinical settings where they have been known to infect blood transfusions 11 See also edit nbsp Wikimedia Commons has media related to Pseudomonas infections References edit Elkin S Geddes D 2003 Pseudomonal infection in cystic fibrosis the battle continues Expert Review of Anti infective Therapy 1 4 609 18 doi 10 1586 14787210 1 4 609 PMID 15482158 S2CID 33383226 Shanson DC 1990 Septicaemia in patients with AIDS Trans R Soc Trop Med Hyg 84 Suppl 1 14 6 doi 10 1016 0035 9203 90 90449 o PMID 2201108 Schaberd Culver Gaynes 1991 Major trends in the microbial etiology of nosocomial infection PDF The American Journal of Medicine 91 3 S72 S75 doi 10 1016 0002 9343 91 90346 Y hdl 2027 42 29131 PMID 1928195 McGowan JE 2006 Resistance in nonfermenting gram negative bacteria multidrug resistance to the maximum Am J Med 119 6 Suppl 1 S29 36 discussion S62 70 doi 10 1016 j amjmed 2006 03 014 PMID 16735148 Obritsch Fish MacLauren Jung 2005 Nosocomial Infections Due to Multidrug Resistant Pseudomonas aeruginosa Epidemiology and Treatment Options Pharmacotherapy 25 10 1353 1364 doi 10 1592 phco 2005 25 10 1353 PMID 16185180 S2CID 36236448 Levitski Heikkila TV Ullian ME 2005 Peritonitis with multiple rare environmental bacteria in a patient receiving long term peritoneal dialysis Am J Kidney Dis 46 6 e119 24 doi 10 1053 j ajkd 2005 08 021 PMID 16310563 Yu EN Foster CS 2002 Chronic postoperative endophthalmitis due to Pseudomonas oryzihabitans Am J Ophthalmol 134 4 613 4 doi 10 1016 S0002 9394 02 01586 6 PMID 12383826 Kodama K Kimura Nm Komagata K 1985 Two new species of Pseudomonas P oryzihabitans isolated from rice paddy and clinical specimens and P luteola isolated from clinical specimens Int J Syst Bacteriol 35 Pt 2 467 74 doi 10 1099 00207713 35 4 467 Nishimori E Kita Tsukamoto K Wakabayashi H 2000 Pseudomonas plecoglossicida sp nov the causative agent of bacterial haemorrhagic ascites of ayu Plecoglossus altivelis Int J Syst Evol Microbiol 50 1 83 9 doi 10 1099 00207713 50 1 83 PMID 10826790 Lopez Romalde S Magarinos B Ravelo C Toranzo AE Romalde JL 2003 Existence of two O serotypes in the fish pathogen Pseudomonas anguilliseptica Vet Microbiol 94 4 325 33 doi 10 1016 S0378 1135 03 00124 X PMID 12829386 Khabbaz RF Arnow PM Highsmith AK et al 1984 Pseudomonas fluorescens bacteremia from blood transfusion Am J Med 76 1 62 8 doi 10 1016 0002 9343 84 90751 4 PMID 6419604 External links edit Retrieved from https en wikipedia org w index php title Pseudomonas infection amp oldid 1209724633, wikipedia, wiki, book, books, library,
