Wikipedia
Propionate—CoA ligase
In enzymology, a propionate—CoA ligase (EC 6.2.1.17) is an enzyme that catalyzes the chemical reaction
Propionate—CoA ligase | |
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Identifiers | |
EC no. | 6.2.1.17 |
CAS no. | 55326-49-3 |
Databases | |
IntEnz | IntEnz view |
BRENDA | BRENDA entry |
ExPASy | NiceZyme view |
KEGG | KEGG entry |
MetaCyc | metabolic pathway |
PRIAM | profile |
PDB structures | RCSB PDB PDBe PDBsum |
Gene Ontology | AmiGO / QuickGO |
- ATP + propanoate + CoA AMP + diphosphate + propanoyl-CoA
The 3 substrates of this enzyme are ATP, propanoate, and CoA, whereas its 3 products are AMP, diphosphate, and propanoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is propanoate:CoA ligase (AMP-forming). This enzyme is also called propionyl-CoA synthetase. This enzyme participates in propanoate metabolism.
References Edit
- Ricks CA, Cook RM (1981). "Regulation of volatile fatty acid uptake by mitochondrial acyl CoA synthetases of bovine liver". Journal of Dairy Science. 64 (12): 2324–35. doi:10.3168/jds.S0022-0302(81)82854-8. PMID 7341659.