Thus, the two substrates of this enzyme are UDP-glucose and 5-(D-galactosyloxy)-L-lysine-procollagen, whereas its two products are UDP and 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase. Other names in common use include galactosylhydroxylysine glucosyltransferase, collagen glucosyltransferase, collagen hydroxylysyl glucosyltransferase, galactosylhydroxylysyl glucosyltransferase, UDP-glucose-collagenglucosyltransferase, and uridine diphosphoglucose-collagen glucosyltransferase.
ReferencesEdit
Bosmann HB, Eylar EH (1968). "Attachment of carbohydrate to collagen. Isolation, purification and properties of the glucosyl transferase". Biochem. Biophys. Res. Commun. 30 (1): 89–94. doi:10.1016/0006-291X(68)90717-1. PMID 5637038.
Bosmann HB, Eylar EH (1968). "Collagen-glucosyl transferase in fibriblasts transformed by oncogenic viruses". Nature. 218 (5141): 582–3. doi:10.1038/218582a0. PMID 4968368.
Butler WT, Cunningham LW (1966). "Evidence for the linkage of a disaccharide to hydroxylysine in tropocollagen". J. Biol. Chem. 241 (17): 3882–8. doi:10.1016/S0021-9258(18)99789-9. PMID 4288358.
Kivirikko KI; Myllyla R (1979). Hall, D.A.; Jackson, D.S. (eds.). "Collagen Glycosyltransferases". International Review of Connective Tissue Research. New York: Academic Press. 8: 23. doi:10.1016/B978-0-12-363708-6.50008-4. ISBN9780123637086. PMID 389860.
procollagen, glucosyltransferase, enzymology, procollagen, glucosyltransferase, enzyme, that, catalyzes, chemical, reactionidentifiersec, 66cas, 9028, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypr. In enzymology a procollagen glucosyltransferase EC 2 4 1 66 is an enzyme that catalyzes the chemical reactionProcollagen glucosyltransferaseIdentifiersEC no 2 4 1 66CAS no 9028 08 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins UDP glucose 5 D galactosyloxy L lysine procollagen displaystyle rightleftharpoons UDP 1 2 D glucosyl 5 D galactosyloxy L lysine procollagenThus the two substrates of this enzyme are UDP glucose and 5 D galactosyloxy L lysine procollagen whereas its two products are UDP and 1 2 D glucosyl 5 D galactosyloxy L lysine procollagen This enzyme belongs to the family of glycosyltransferases specifically the hexosyltransferases The systematic name of this enzyme class is UDP glucose 5 D galactosyloxy L lysine procollagen D glucosyltransferase Other names in common use include galactosylhydroxylysine glucosyltransferase collagen glucosyltransferase collagen hydroxylysyl glucosyltransferase galactosylhydroxylysyl glucosyltransferase UDP glucose collagenglucosyltransferase and uridine diphosphoglucose collagen glucosyltransferase References EditBosmann HB Eylar EH 1968 Attachment of carbohydrate to collagen Isolation purification and properties of the glucosyl transferase Biochem Biophys Res Commun 30 1 89 94 doi 10 1016 0006 291X 68 90717 1 PMID 5637038 Bosmann HB Eylar EH 1968 Collagen glucosyl transferase in fibriblasts transformed by oncogenic viruses Nature 218 5141 582 3 doi 10 1038 218582a0 PMID 4968368 Butler WT Cunningham LW 1966 Evidence for the linkage of a disaccharide to hydroxylysine in tropocollagen J Biol Chem 241 17 3882 8 doi 10 1016 S0021 9258 18 99789 9 PMID 4288358 Kivirikko KI Myllyla R 1979 Hall D A Jackson D S eds Collagen Glycosyltransferases International Review of Connective Tissue Research New York Academic Press 8 23 doi 10 1016 B978 0 12 363708 6 50008 4 ISBN 9780123637086 PMID 389860 Portal Biology This EC 2 4 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Procollagen glucosyltransferase amp oldid 1172358260, wikipedia, wiki, book, books, library,
