Presence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern
Round or oval nests (insulae) or in trabeculae.
Solid growth and presence of microfollicles, some of which contain dense colloid.
Extrathyroidal extension and blood vessel invasion
Foci of necrosis,
Larger than 5 cm in greatest diameter at diagnosis
Epidemiologyedit
PDTC affects predominantly females about 55 years of age
Referencesedit
^Volante M, Collini P, Nikiforov YE, Sakamoto A, Kakudo K, Katoh R, Lloyd RV, LiVolsi VA, Papotti M, Sobrinho-Simoes M, Bussolati G, Rosai J (2007). "Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach". Am J Surg Pathol. 31 (8): 1256–64. doi:10.1097/PAS.0b013e3180309e6a. PMID 17667551. S2CID 41666642.
External linksedit
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poorly, differentiated, thyroid, cancer, poorly, differentiated, thyroid, carcinoma, malignant, neoplasm, follicular, cell, origin, showing, intermediate, histopathological, patterns, between, differentiated, undifferentiated, thyroid, cancers, poorly, differe. Poorly differentiated thyroid carcinoma is malignant neoplasm of follicular cell origin showing intermediate histopathological patterns between differentiated and undifferentiated thyroid cancers 1 Poorly differentiated thyroid carcinomaOther namesPDTCSpecialtyOncology Contents 1 Histopathology 2 Epidemiology 3 References 4 External linksHistopathology editPresence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern Round or oval nests insulae or in trabeculae Solid growth and presence of microfollicles some of which contain dense colloid Extrathyroidal extension and blood vessel invasion Foci of necrosis Larger than 5 cm in greatest diameter at diagnosisEpidemiology editPDTC affects predominantly females about 55 years of ageReferences edit Volante M Collini P Nikiforov YE Sakamoto A Kakudo K Katoh R Lloyd RV LiVolsi VA Papotti M Sobrinho Simoes M Bussolati G Rosai J 2007 Poorly differentiated thyroid carcinoma the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach Am J Surg Pathol 31 8 1256 64 doi 10 1097 PAS 0b013e3180309e6a PMID 17667551 S2CID 41666642 External links edit nbsp This oncology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Poorly differentiated thyroid cancer amp oldid 1036203110, wikipedia, wiki, book, books, library,
