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Pol (HIV)

Pol (DNA polymerase) refers to a gene in retroviruses, or the protein produced by that gene.

The Gag-Pol region containing the protease gene flanked by p6pol at the N-terminus and reverse transcriptase at the C-terminus.

Products of pol include:

Reverse transcriptase edit

Common to all retroviruses, this enzyme transcribes the viral RNA into double-stranded DNA.

Integrase edit

This enzyme integrates the DNA produced by reverse transcriptase into the host's genome.

Protease edit

A protease is any enzyme that cuts proteins into segments. HIV's gag and pol genes do not produce their proteins in their final form, but as larger combination proteins; the specific protease used by HIV cleaves these into separate functional units. Protease inhibitor drugs block this step.

See also edit

External links edit

this, article, does, cite, sources, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, books, scholar, jstor, february, 2023, learn, when, remove, this, templat. This article does not cite any sources Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Pol HIV news newspapers books scholar JSTOR February 2023 Learn how and when to remove this template message Pol DNA polymerase refers to a gene in retroviruses or the protein produced by that gene The Gag Pol region containing the protease gene flanked by p6pol at the N terminus and reverse transcriptase at the C terminus Products of pol include Contents 1 Reverse transcriptase 2 Integrase 3 Protease 4 See also 5 External linksReverse transcriptase editMain article Reverse transcriptase Common to all retroviruses this enzyme transcribes the viral RNA into double stranded DNA Integrase editMain article Integrase This enzyme integrates the DNA produced by reverse transcriptase into the host s genome Protease editMain article HIV 1 protease A protease is any enzyme that cuts proteins into segments HIV s gag and pol genes do not produce their proteins in their final form but as larger combination proteins the specific protease used by HIV cleaves these into separate functional units Protease inhibitor drugs block this step See also editGag pol translational readthrough siteExternal links editGene Products pol at the U S National Library of Medicine Medical Subject Headings MeSH pol Gene Products Human Immunodeficiency Virus at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This virus related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Pol HIV amp oldid 1139853623, wikipedia, wiki, book, books, library,

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