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Periarteriolar lymphoid sheaths

Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen. They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.

In contrast, the lymphoid portions of the white pulp are dominated by B cells.

External links edit

  • Histology image: 07703loa – Histology Learning System at Boston University
  • Histology image: 62_06 at the University of Oklahoma Health Sciences Center

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