Karrer was born in Moscow, Russia to Paul Karrer and Julie Lerch, both Swiss nationals. In 1892 Karrer's family returned to Switzerland where he was educated at Wildegg and at the grammar school in Lenzburg, Aarau, where he matriculated in 1908. He studied chemistry at the University of Zurich under Alfred Werner and after gaining his Ph.D. in 1911, he spent a further year as assistant in the Chemical Institute. He then took a post as chemist with Paul Ehrlich at the Georg Speyer Haus, Frankfurt-am-Main. In 1919 he became Professor of Chemistry and Director of the Chemical Institute.
Research
Karrer's early research concerned complex metal compounds but his most important work has concerned plant pigments, particularly the yellow carotenoids. He elucidated their chemical structure and showed that some of these substances are transformed in the body into vitamin A. His work led to the establishment of the correct constitutional formula for beta-carotene, the chief precursor of vitamin A; the first time that the structure of a vitamin or provitamin had been established. George Wald worked briefly in Karrer's lab while studying the role of vitamin A in the retina. Later, Karrer confirmed the structure of ascorbic acid (vitamin C) and extended his researches into the vitamin B2 and E. His important contributions to the chemistry of the flavins led to identification of lactoflavin as part of the complex originally thought to be vitamin B2.
Karrer published many papers, and received many honours and awards, including the Nobel Prize in 1937. His textbook Lehrbuch der Organischen Chemie (Textbook of Organic Chemistry) was published in 1927, went through thirteen editions, and was published in seven languages.[citation needed]
Personal life
Karrer was married to Helena Froelich in 1914 and had three sons, one of whom died in infancy.[1] He died on 18 June 1971, at the age of 82 in Zürich. His wife died in 1972.[citation needed]
Legacy
The prestigious Paul Karrer Gold Medal and lecture was established in his honour in 1959 by a group of leading companies such as CIBA AG, J.R. Geigy, F. Hoffmann-La Roche & Co. AG, Sandoz AG, Société des Produits Nestlé AG and Dr. A. Wander AG. It is awarded annually or biannually to an outstanding chemist who delivers a lecture at the University of Zurich.[2]
The Paul Karrer Lecture Foundation is based at the Chemistry Institute of the University of Zurich at Rämistrasse 71, in Zürich. [3]
References
Sources
Shampo; Kyle, RA (2000). "Paul Karrer—research on vitamins". Mayo Clinic Proceedings. 75 (4): 328. doi:10.4065/75.4.328. PMID 10761480.
Isler (1978). "Paul Karrer, 21 April 1889—18 June 1971". Biographical Memoirs of Fellows of the Royal Society. 24: 245–321. doi:10.1098/rsbm.1978.0009. PMID 11615740. S2CID 7389730.
Schmid (1972). "Paul Karrer, 1889–1971". Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften. 28 (5): 367–70. PMID 4566692.
Roche (1972). "Paul Karrer (1889–1971)". Bulletin de l'Académie Nationale de Médecine. 156 (4): 89–92. PMID 4565808.
Karrer; Viscontini, M; Hochreuter, R (1953). "Crystallized 3-carboxamide-N1-D-ribosidopyridinium bromide and related compounds". Biochimica et Biophysica Acta. 12 (1–2): 51–5. doi:10.1016/0006-3002(53)90122-x. PMID 13115412.
Paul Karrer on Nobelprize.org including the Nobel Lecture, 11 December 1937 Carotenoids, Flavins and Vitamin A and B2
June 02, 2023
paul, karrer, this, article, includes, list, general, references, lacks, sufficient, corresponding, inline, citations, please, help, improve, this, article, introducing, more, precise, citations, october, 2009, learn, when, remove, this, template, message, pro. This article includes a list of general references but it lacks sufficient corresponding inline citations Please help to improve this article by introducing more precise citations October 2009 Learn how and when to remove this template message Professor Paul Karrer FRS FRSE FCS 21 April 1889 18 June 1971 was a Swiss organic chemist best known for his research on vitamins He and Norman Haworth won the Nobel Prize for Chemistry in 1937 Paul KarrerBorn 1889 04 21 21 April 1889Moscow RussiaDied18 June 1971 1971 06 18 aged 82 Zurich SwitzerlandNationalitySwissAlma materUniversitat ZurichKnown forVitaminsAwardsMarcel Benoist Prize 1922 Nobel Prize for Chemistry 1937 Scientific careerFieldsChemistryInstitutionsUniversitat Zurich Contents 1 Biography 1 1 Early years 1 2 Research 1 3 Personal life 2 Legacy 3 References 4 External linksBiography EditEarly years Edit Karrer was born in Moscow Russia to Paul Karrer and Julie Lerch both Swiss nationals In 1892 Karrer s family returned to Switzerland where he was educated at Wildegg and at the grammar school in Lenzburg Aarau where he matriculated in 1908 He studied chemistry at the University of Zurich under Alfred Werner and after gaining his Ph D in 1911 he spent a further year as assistant in the Chemical Institute He then took a post as chemist with Paul Ehrlich at the Georg Speyer Haus Frankfurt am Main In 1919 he became Professor of Chemistry and Director of the Chemical Institute Research Edit Karrer s early research concerned complex metal compounds but his most important work has concerned plant pigments particularly the yellow carotenoids He elucidated their chemical structure and showed that some of these substances are transformed in the body into vitamin A His work led to the establishment of the correct constitutional formula for beta carotene the chief precursor of vitamin A the first time that the structure of a vitamin or provitamin had been established George Wald worked briefly in Karrer s lab while studying the role of vitamin A in the retina Later Karrer confirmed the structure of ascorbic acid vitamin C and extended his researches into the vitamin B2 and E His important contributions to the chemistry of the flavins led to identification of lactoflavin as part of the complex originally thought to be vitamin B2 Karrer published many papers and received many honours and awards including the Nobel Prize in 1937 His textbook Lehrbuch der Organischen Chemie Textbook of Organic Chemistry was published in 1927 went through thirteen editions and was published in seven languages citation needed Personal life Edit Karrer was married to Helena Froelich in 1914 and had three sons one of whom died in infancy 1 He died on 18 June 1971 at the age of 82 in Zurich His wife died in 1972 citation needed Legacy EditThe prestigious Paul Karrer Gold Medal and lecture was established in his honour in 1959 by a group of leading companies such as CIBA AG J R Geigy F Hoffmann La Roche amp Co AG Sandoz AG Societe des Produits Nestle AG and Dr A Wander AG It is awarded annually or biannually to an outstanding chemist who delivers a lecture at the University of Zurich 2 The Paul Karrer Lecture Foundation is based at the Chemistry Institute of the University of Zurich at Ramistrasse 71 in Zurich 3 References EditSourcesShampo Kyle RA 2000 Paul Karrer research on vitamins Mayo Clinic Proceedings 75 4 328 doi 10 4065 75 4 328 PMID 10761480 Isler 1978 Paul Karrer 21 April 1889 18 June 1971 Biographical Memoirs of Fellows of the Royal Society 24 245 321 doi 10 1098 rsbm 1978 0009 PMID 11615740 S2CID 7389730 Schmid 1972 Paul Karrer 1889 1971 Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften 28 5 367 70 PMID 4566692 Roche 1972 Paul Karrer 1889 1971 Bulletin de l Academie Nationale de Medecine 156 4 89 92 PMID 4565808 Karrer Viscontini M Hochreuter R 1953 Crystallized 3 carboxamide N1 D ribosidopyridinium bromide and related compounds Biochimica et Biophysica Acta 12 1 2 51 5 doi 10 1016 0006 3002 53 90122 x PMID 13115412 Notes Isler page 245 Paul Karrer Lecture University of Zurich Archived from the original on 20 January 2015 Retrieved 20 January 2015 Paul Karrer Vorlesung Institut fur Chemie External links EditPaul Karrer on Nobelprize org including the Nobel Lecture 11 December 1937 Carotenoids Flavins and Vitamin A and B2 Retrieved from https en wikipedia org w index php title Paul Karrer amp oldid 1149570243, wikipedia, wiki, book, books, library,
